Surface physical chemistry properties in coated bacterial cellulose membranes with calcium phosphate

• Autor(a) principal: de Olyveira, Gabriel Molina [UNESP]
• Data de Publicação: 2017
• Outros Autores: Basmaji, Pierre, Costa, Ligia Maria Manzine, dos Santos, Márcio Luiz, dos Santos Riccardi, Carla [UNESP], Guastaldi, Fernando Pozzi Semeghini [UNESP], Scarel-Caminaga, Raquel Mantuaneli [UNESP], de Oliveira Capote, Ticiana Sidorenko [UNESP], Pizoni, Elisabeth [UNESP], Guastaldi, Antônio Carlos [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1016/j.msec.2017.03.025; http://hdl.handle.net/11449/174335
• topic: Bacterial cellulose; Coated membrane; Regenerative medicine; Tissue regeneration

Bacterial cellulose has become established as a new biomaterial, and it can be used for medical applications. In addition, it has called attention due to the increasing interest in tissue engineering materials for wound care. In this work, the bacterial cellulose fermentation process was modified by the addition of chondroitin sulfate to the culture medium before the inoculation of the bacteria. The biomimetic process with heterogeneous calcium phosphate precipitation of biological interest was studied for the guided regeneration purposes on bacterial cellulose. FTIR results showed the incorporation of the chondroitin sulfate in the bacterial cellulose, SEM images confirmed the deposition of the calcium phosphate on the bacterial cellulose surface, XPS analysis showed a selective chemical group influences which change calcium phosphate deposition, besides, the calcium phosphate phase with different Ca/P ratios on bacterial cellulose surface influences wettability. XTT results concluded that these materials did not affect significantly in the cell viability, being non-cytotoxic. Thus, it was produced one biomaterial with the surface charge changes for calcium phosphate deposition, besides different wettability which builds new membranes for Guided Tissue Regeneration.