Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.jdent.2020.103570 http://hdl.handle.net/11449/207137 |
Resumo: | Objective: To evaluate the influence of fluoride varnish (FV) therapies or resin infiltration (RI) to maintain the structural integrity of Molar Incisor Hypomineralization (MIH) -affected teeth. Methods: Fifty-one children aged 6–12 years with at least one incisor and one first permanent molar with yellow/brown MIH opacities were included. Patients were randomly allocated into three groups: FV – Fluoride Varnish (Duraphat); FV+etch – Fluoride Varnish (Duraphat) after enamel etching with 37% phosphoric acid; or RI – Resin Infiltration system (Icon). Opacities were monitored for 18 months. The primary outcome was the loss of integrity due to post-eruptive enamel breakdown (PEB). Covariables included sex, age, DMFT index, opacity colour, plaque index, number of MIH-affected teeth, and number of MIH-affected surfaces. Fisher's Exact was used to test the association of treatments with PEB, the Kaplan-Meyer method analysed the survival rates and Cox-regression determined which covariables would predict failure (α=0.05). Results: From a total of 235 teeth, the PEB rate for RI (6.1%) was significantly lower (p<0.05) than FV (17.9%; OR 3.0, 95%CI 1.07, 8.48) and FV+etch (17.3%; OR 3.1, 95%CI 1.13, 8.73). DMFT index >3, brown opacities, cusp involvement, and age between 6–8 years predicted PEB (p<0.05). Conclusions: Resin infiltration positively influenced the structural integrity maintenance of MIH-affected teeth by decreasing the risk of enamel breakdown over18 months follow-up. Registry of Clinical Trials (RBR-8wwk3n). Clinical Relevance: Resin infiltration proved to be a more efficacious intervention to maintain the structural integrity of MIH-affected teeth than fluoride varnish therapies. |
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Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trialDental enamelEnamel defectsFluoride therapyIconMolar incisor hypomineralizationResin infiltrationObjective: To evaluate the influence of fluoride varnish (FV) therapies or resin infiltration (RI) to maintain the structural integrity of Molar Incisor Hypomineralization (MIH) -affected teeth. Methods: Fifty-one children aged 6–12 years with at least one incisor and one first permanent molar with yellow/brown MIH opacities were included. Patients were randomly allocated into three groups: FV – Fluoride Varnish (Duraphat); FV+etch – Fluoride Varnish (Duraphat) after enamel etching with 37% phosphoric acid; or RI – Resin Infiltration system (Icon). Opacities were monitored for 18 months. The primary outcome was the loss of integrity due to post-eruptive enamel breakdown (PEB). Covariables included sex, age, DMFT index, opacity colour, plaque index, number of MIH-affected teeth, and number of MIH-affected surfaces. Fisher's Exact was used to test the association of treatments with PEB, the Kaplan-Meyer method analysed the survival rates and Cox-regression determined which covariables would predict failure (α=0.05). Results: From a total of 235 teeth, the PEB rate for RI (6.1%) was significantly lower (p<0.05) than FV (17.9%; OR 3.0, 95%CI 1.07, 8.48) and FV+etch (17.3%; OR 3.1, 95%CI 1.13, 8.73). DMFT index >3, brown opacities, cusp involvement, and age between 6–8 years predicted PEB (p<0.05). Conclusions: Resin infiltration positively influenced the structural integrity maintenance of MIH-affected teeth by decreasing the risk of enamel breakdown over18 months follow-up. Registry of Clinical Trials (RBR-8wwk3n). Clinical Relevance: Resin infiltration proved to be a more efficacious intervention to maintain the structural integrity of MIH-affected teeth than fluoride varnish therapies.Department of Morphology and Pediatric Dentistry Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680Department of Dental Materials and Prosthodontics Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680Melbourne Dental School The University of MelbourneCariology and Paediatric Dentistry Centrum voor Tandheelkunde en Mondzorgkunde UMCG University of GroningenDepartment of Morphology and Pediatric Dentistry Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680Department of Dental Materials and Prosthodontics Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680Universidade Estadual Paulista (Unesp)The University of MelbourneUniversity of GroningenNogueira, Vinícius Krieger Costa [UNESP]Mendes Soares, Igor Paulino [UNESP]Fragelli, Camila Maria Bullio [UNESP]Boldieri, Talita [UNESP]Manton, David JohnBussaneli, Diego Girotto [UNESP]Cordeiro, Rita de Cássia Loiola [UNESP]2021-06-25T10:49:35Z2021-06-25T10:49:35Z2021-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.jdent.2020.103570Journal of Dentistry, v. 105.0300-5712http://hdl.handle.net/11449/20713710.1016/j.jdent.2020.1035702-s2.0-85099377120Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Dentistryinfo:eu-repo/semantics/openAccess2021-10-23T16:16:11Zoai:repositorio.unesp.br:11449/207137Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:16:31.384183Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial |
title |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial |
spellingShingle |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial Nogueira, Vinícius Krieger Costa [UNESP] Dental enamel Enamel defects Fluoride therapy Icon Molar incisor hypomineralization Resin infiltration |
title_short |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial |
title_full |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial |
title_fullStr |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial |
title_full_unstemmed |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial |
title_sort |
Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial |
author |
Nogueira, Vinícius Krieger Costa [UNESP] |
author_facet |
Nogueira, Vinícius Krieger Costa [UNESP] Mendes Soares, Igor Paulino [UNESP] Fragelli, Camila Maria Bullio [UNESP] Boldieri, Talita [UNESP] Manton, David John Bussaneli, Diego Girotto [UNESP] Cordeiro, Rita de Cássia Loiola [UNESP] |
author_role |
author |
author2 |
Mendes Soares, Igor Paulino [UNESP] Fragelli, Camila Maria Bullio [UNESP] Boldieri, Talita [UNESP] Manton, David John Bussaneli, Diego Girotto [UNESP] Cordeiro, Rita de Cássia Loiola [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) The University of Melbourne University of Groningen |
dc.contributor.author.fl_str_mv |
Nogueira, Vinícius Krieger Costa [UNESP] Mendes Soares, Igor Paulino [UNESP] Fragelli, Camila Maria Bullio [UNESP] Boldieri, Talita [UNESP] Manton, David John Bussaneli, Diego Girotto [UNESP] Cordeiro, Rita de Cássia Loiola [UNESP] |
dc.subject.por.fl_str_mv |
Dental enamel Enamel defects Fluoride therapy Icon Molar incisor hypomineralization Resin infiltration |
topic |
Dental enamel Enamel defects Fluoride therapy Icon Molar incisor hypomineralization Resin infiltration |
description |
Objective: To evaluate the influence of fluoride varnish (FV) therapies or resin infiltration (RI) to maintain the structural integrity of Molar Incisor Hypomineralization (MIH) -affected teeth. Methods: Fifty-one children aged 6–12 years with at least one incisor and one first permanent molar with yellow/brown MIH opacities were included. Patients were randomly allocated into three groups: FV – Fluoride Varnish (Duraphat); FV+etch – Fluoride Varnish (Duraphat) after enamel etching with 37% phosphoric acid; or RI – Resin Infiltration system (Icon). Opacities were monitored for 18 months. The primary outcome was the loss of integrity due to post-eruptive enamel breakdown (PEB). Covariables included sex, age, DMFT index, opacity colour, plaque index, number of MIH-affected teeth, and number of MIH-affected surfaces. Fisher's Exact was used to test the association of treatments with PEB, the Kaplan-Meyer method analysed the survival rates and Cox-regression determined which covariables would predict failure (α=0.05). Results: From a total of 235 teeth, the PEB rate for RI (6.1%) was significantly lower (p<0.05) than FV (17.9%; OR 3.0, 95%CI 1.07, 8.48) and FV+etch (17.3%; OR 3.1, 95%CI 1.13, 8.73). DMFT index >3, brown opacities, cusp involvement, and age between 6–8 years predicted PEB (p<0.05). Conclusions: Resin infiltration positively influenced the structural integrity maintenance of MIH-affected teeth by decreasing the risk of enamel breakdown over18 months follow-up. Registry of Clinical Trials (RBR-8wwk3n). Clinical Relevance: Resin infiltration proved to be a more efficacious intervention to maintain the structural integrity of MIH-affected teeth than fluoride varnish therapies. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T10:49:35Z 2021-06-25T10:49:35Z 2021-02-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.jdent.2020.103570 Journal of Dentistry, v. 105. 0300-5712 http://hdl.handle.net/11449/207137 10.1016/j.jdent.2020.103570 2-s2.0-85099377120 |
url |
http://dx.doi.org/10.1016/j.jdent.2020.103570 http://hdl.handle.net/11449/207137 |
identifier_str_mv |
Journal of Dentistry, v. 105. 0300-5712 10.1016/j.jdent.2020.103570 2-s2.0-85099377120 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Dentistry |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128782013300736 |