Porous titanium scaffolds produced by powder metallurgy for biomedical applications

Detalhes bibliográficos
Autor(a) principal: Vasconcellos, Luana Marotta Reis de [UNESP]
Data de Publicação: 2008
Outros Autores: Oliveira, Marize Varella de, Alencastro Graça, Mário Lima de, Vasconcellos, Luis Gustavo Oliveira de [UNESP], Carvalho, Yasmin Rodarte [UNESP], Cairo, Carlos Alberto Alves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1516-14392008000300008
http://hdl.handle.net/11449/70458
Resumo: Porous titanium scaffolds are promising materials for biomedical applications such as prosthetic anchors, fillers and bone reconstruction. This study evaluated the bone/titanium interface of scaffolds with interconnected pores prepared by powder metallurgy, using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Porous scaffolds and dense samples were implanted in the tibia of rabbits, which were subsequently killed 1, 4, and 8 weeks after surgery. Initial bone neoformation was observed one week after implantation. Bone ingrowth in pores and the Ca/P ratio at the interface were remarkably enhanced at 4 and 8 weeks. The results showed that the interconnected pores of the titanium scaffolds promoted bone ingrowth, which increased over time. The powder metallurgy technique thus proved effective in producing porous scaffolds and dense titanium for biomedical applications, allowing for adequate control of pore size and porosity and promoting bone ingrowth.
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spelling Porous titanium scaffolds produced by powder metallurgy for biomedical applicationsBiomedicalOsseointegrationPorosityTitaniumAluminum powder metallurgyApplicationsBoneInterconnection networksMetallurgyOresPowder metallurgyPowdersBiomedical applicationsBone ingrowthsBone reconstructionsCa/P ratiosInterconnected poresPorous scaffoldsPorous titaniumsPromising materialsTitanium scaffoldsScaffoldsPorous titanium scaffolds are promising materials for biomedical applications such as prosthetic anchors, fillers and bone reconstruction. This study evaluated the bone/titanium interface of scaffolds with interconnected pores prepared by powder metallurgy, using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Porous scaffolds and dense samples were implanted in the tibia of rabbits, which were subsequently killed 1, 4, and 8 weeks after surgery. Initial bone neoformation was observed one week after implantation. Bone ingrowth in pores and the Ca/P ratio at the interface were remarkably enhanced at 4 and 8 weeks. The results showed that the interconnected pores of the titanium scaffolds promoted bone ingrowth, which increased over time. The powder metallurgy technique thus proved effective in producing porous scaffolds and dense titanium for biomedical applications, allowing for adequate control of pore size and porosity and promoting bone ingrowth.Department of Bioscience and Buccal Diagnosis São Jose dos Campos School of Dentistry State University of Sõ Paulo - UNESP, Av. Engenheiro Francisco José Longo, 777, 12245-000 São José dos Campos - SPNational Institute of Technology, Av. Venezuela, 200, Rio de Janeiro - RJDepartment of Materials Air and Space Institute CTA, Praça Mal. do Ar Eduardo Gomes, 14, 12904-000 São José dos Campos - SPDepartment of Bioscience and Buccal Diagnosis São Jose dos Campos School of Dentistry State University of Sõ Paulo - UNESP, Av. Engenheiro Francisco José Longo, 777, 12245-000 São José dos Campos - SPUniversidade Estadual Paulista (Unesp)National Institute of TechnologyCTAVasconcellos, Luana Marotta Reis de [UNESP]Oliveira, Marize Varella deAlencastro Graça, Mário Lima deVasconcellos, Luis Gustavo Oliveira de [UNESP]Carvalho, Yasmin Rodarte [UNESP]Cairo, Carlos Alberto Alves2014-05-27T11:23:35Z2014-05-27T11:23:35Z2008-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article275-280application/pdfhttp://dx.doi.org/10.1590/S1516-14392008000300008Materials Research, v. 11, n. 3, p. 275-280, 2008.1516-1439http://hdl.handle.net/11449/7045810.1590/S1516-14392008000300008S1516-14392008000300008WOS:0002612354000082-s2.0-573491556702-s2.0-57349155670.pdf69673691197921515006685136114327Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterials Research1.1030,398info:eu-repo/semantics/openAccess2023-10-16T06:09:40Zoai:repositorio.unesp.br:11449/70458Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-16T06:09:40Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Porous titanium scaffolds produced by powder metallurgy for biomedical applications
title Porous titanium scaffolds produced by powder metallurgy for biomedical applications
spellingShingle Porous titanium scaffolds produced by powder metallurgy for biomedical applications
Vasconcellos, Luana Marotta Reis de [UNESP]
Biomedical
Osseointegration
Porosity
Titanium
Aluminum powder metallurgy
Applications
Bone
Interconnection networks
Metallurgy
Ores
Powder metallurgy
Powders
Biomedical applications
Bone ingrowths
Bone reconstructions
Ca/P ratios
Interconnected pores
Porous scaffolds
Porous titaniums
Promising materials
Titanium scaffolds
Scaffolds
title_short Porous titanium scaffolds produced by powder metallurgy for biomedical applications
title_full Porous titanium scaffolds produced by powder metallurgy for biomedical applications
title_fullStr Porous titanium scaffolds produced by powder metallurgy for biomedical applications
title_full_unstemmed Porous titanium scaffolds produced by powder metallurgy for biomedical applications
title_sort Porous titanium scaffolds produced by powder metallurgy for biomedical applications
author Vasconcellos, Luana Marotta Reis de [UNESP]
author_facet Vasconcellos, Luana Marotta Reis de [UNESP]
Oliveira, Marize Varella de
Alencastro Graça, Mário Lima de
Vasconcellos, Luis Gustavo Oliveira de [UNESP]
Carvalho, Yasmin Rodarte [UNESP]
Cairo, Carlos Alberto Alves
author_role author
author2 Oliveira, Marize Varella de
Alencastro Graça, Mário Lima de
Vasconcellos, Luis Gustavo Oliveira de [UNESP]
Carvalho, Yasmin Rodarte [UNESP]
Cairo, Carlos Alberto Alves
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
National Institute of Technology
CTA
dc.contributor.author.fl_str_mv Vasconcellos, Luana Marotta Reis de [UNESP]
Oliveira, Marize Varella de
Alencastro Graça, Mário Lima de
Vasconcellos, Luis Gustavo Oliveira de [UNESP]
Carvalho, Yasmin Rodarte [UNESP]
Cairo, Carlos Alberto Alves
dc.subject.por.fl_str_mv Biomedical
Osseointegration
Porosity
Titanium
Aluminum powder metallurgy
Applications
Bone
Interconnection networks
Metallurgy
Ores
Powder metallurgy
Powders
Biomedical applications
Bone ingrowths
Bone reconstructions
Ca/P ratios
Interconnected pores
Porous scaffolds
Porous titaniums
Promising materials
Titanium scaffolds
Scaffolds
topic Biomedical
Osseointegration
Porosity
Titanium
Aluminum powder metallurgy
Applications
Bone
Interconnection networks
Metallurgy
Ores
Powder metallurgy
Powders
Biomedical applications
Bone ingrowths
Bone reconstructions
Ca/P ratios
Interconnected pores
Porous scaffolds
Porous titaniums
Promising materials
Titanium scaffolds
Scaffolds
description Porous titanium scaffolds are promising materials for biomedical applications such as prosthetic anchors, fillers and bone reconstruction. This study evaluated the bone/titanium interface of scaffolds with interconnected pores prepared by powder metallurgy, using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Porous scaffolds and dense samples were implanted in the tibia of rabbits, which were subsequently killed 1, 4, and 8 weeks after surgery. Initial bone neoformation was observed one week after implantation. Bone ingrowth in pores and the Ca/P ratio at the interface were remarkably enhanced at 4 and 8 weeks. The results showed that the interconnected pores of the titanium scaffolds promoted bone ingrowth, which increased over time. The powder metallurgy technique thus proved effective in producing porous scaffolds and dense titanium for biomedical applications, allowing for adequate control of pore size and porosity and promoting bone ingrowth.
publishDate 2008
dc.date.none.fl_str_mv 2008-07-01
2014-05-27T11:23:35Z
2014-05-27T11:23:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1516-14392008000300008
Materials Research, v. 11, n. 3, p. 275-280, 2008.
1516-1439
http://hdl.handle.net/11449/70458
10.1590/S1516-14392008000300008
S1516-14392008000300008
WOS:000261235400008
2-s2.0-57349155670
2-s2.0-57349155670.pdf
6967369119792151
5006685136114327
url http://dx.doi.org/10.1590/S1516-14392008000300008
http://hdl.handle.net/11449/70458
identifier_str_mv Materials Research, v. 11, n. 3, p. 275-280, 2008.
1516-1439
10.1590/S1516-14392008000300008
S1516-14392008000300008
WOS:000261235400008
2-s2.0-57349155670
2-s2.0-57349155670.pdf
6967369119792151
5006685136114327
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Materials Research
1.103
0,398
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 275-280
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799964590052737024

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