Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.resp.2019.103317 http://hdl.handle.net/11449/199608 |
Resumo: | The concentration of CO2 in the environment surrounding the embryo impacts development and may also influence the cardiorespiratory responses after hatching. Therefore, we aimed to evaluate the cardiorespiratory and thermal responses to hypercapnia in chicks that were exposed to CO2 during embryonic development, i.e., incubation. Embryos were incubated without and with a gradual increase in CO2 concentration up to 1 % during the first ten days of incubation. Ten-day-old chicks (males and females) were again acutely exposed to hypercapnia (7 % CO2), or to room air (normocapnia) and pulmonary ventilation, arterial pH and blood gases, arterial blood pressure and heart rate, body temperature (Tb) and oxygen consumption (V⋅O2) were measured. Compared to control animals, male chicks incubated with 1 % CO2 presented an attenuated ventilatory response to hypercapnia (P < 0.05), whereas no difference was found in the hypercapnic ventilatory response in both female chick groups (0 % vs 1 % CO2 incubation). Hypercapnia induced bradycardia in all groups (P < 0.001). The CO2 exposure during incubation did not alter the cardiovascular responses to hypercapnia in post-hatch animals. There were no significant effects of incubation treatment (0 % vs 1 % CO2) or sex in the mean arterial pressure, Tb, and V⋅O2 of animals in normocapnia and hypercapnia. As for the V⋅E/V⋅O2, hypercapnia caused an increase in both groups (P < 0.05), regardless of incubation treatment. In conclusion, among cardiorespiratory and metabolic variables, the ventilatory response to hypercapnia can be attenuated by pre-exposure to 1 % CO2 during embryonic development, especially in male chicks up to 10 days. |
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Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic developmentArterial pressure and heart rateBody temperatureChicken embryoChicksCO2 exposureEmbryonic developmentMetabolic ratePulmonary ventilationThe concentration of CO2 in the environment surrounding the embryo impacts development and may also influence the cardiorespiratory responses after hatching. Therefore, we aimed to evaluate the cardiorespiratory and thermal responses to hypercapnia in chicks that were exposed to CO2 during embryonic development, i.e., incubation. Embryos were incubated without and with a gradual increase in CO2 concentration up to 1 % during the first ten days of incubation. Ten-day-old chicks (males and females) were again acutely exposed to hypercapnia (7 % CO2), or to room air (normocapnia) and pulmonary ventilation, arterial pH and blood gases, arterial blood pressure and heart rate, body temperature (Tb) and oxygen consumption (V⋅O2) were measured. Compared to control animals, male chicks incubated with 1 % CO2 presented an attenuated ventilatory response to hypercapnia (P < 0.05), whereas no difference was found in the hypercapnic ventilatory response in both female chick groups (0 % vs 1 % CO2 incubation). Hypercapnia induced bradycardia in all groups (P < 0.001). The CO2 exposure during incubation did not alter the cardiovascular responses to hypercapnia in post-hatch animals. There were no significant effects of incubation treatment (0 % vs 1 % CO2) or sex in the mean arterial pressure, Tb, and V⋅O2 of animals in normocapnia and hypercapnia. As for the V⋅E/V⋅O2, hypercapnia caused an increase in both groups (P < 0.05), regardless of incubation treatment. In conclusion, among cardiorespiratory and metabolic variables, the ventilatory response to hypercapnia can be attenuated by pre-exposure to 1 % CO2 during embryonic development, especially in male chicks up to 10 days.Department of Animal Morphology and Physiology College of Agricultural and Veterinarian Sciences São Paulo State University (FCAV/UNESP)National Institute of Science and Technology – Comparative Physiology (INCT- Fisiologia Comparada)Current address: Institute of Biological Science Department of Physiology and Biophysics Federal University of Minas Gerais (ICB/UFMG)Department of Animal Morphology and Physiology College of Agricultural and Veterinarian Sciences São Paulo State University (FCAV/UNESP)Universidade Estadual Paulista (Unesp)National Institute of Science and Technology – Comparative Physiology (INCT- Fisiologia Comparada)Universidade Federal de Minas Gerais (UFMG)Rocha, Aline C.G. [UNESP]Espinha, L.ívia P. [UNESP]Santos, Kassia M. [UNESP]Almeida, Ayla R. [UNESP]Macari, Marcos [UNESP]Bícego, Kênia C. [UNESP]Gargaglioni, Luciane H. [UNESP]da Silva, Glauber S.F. [UNESP]2020-12-12T01:44:27Z2020-12-12T01:44:27Z2020-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.resp.2019.103317Respiratory Physiology and Neurobiology, v. 273.1878-15191569-9048http://hdl.handle.net/11449/19960810.1016/j.resp.2019.1033172-s2.0-85074535876Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRespiratory Physiology and Neurobiologyinfo:eu-repo/semantics/openAccess2024-06-06T18:42:13Zoai:repositorio.unesp.br:11449/199608Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-06-06T18:42:13Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development |
title |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development |
spellingShingle |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development Rocha, Aline C.G. [UNESP] Arterial pressure and heart rate Body temperature Chicken embryo Chicks CO2 exposure Embryonic development Metabolic rate Pulmonary ventilation |
title_short |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development |
title_full |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development |
title_fullStr |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development |
title_full_unstemmed |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development |
title_sort |
Cardiorespiratory and thermal responses to hypercapnia in chickens exposed to CO2 during embryonic development |
author |
Rocha, Aline C.G. [UNESP] |
author_facet |
Rocha, Aline C.G. [UNESP] Espinha, L.ívia P. [UNESP] Santos, Kassia M. [UNESP] Almeida, Ayla R. [UNESP] Macari, Marcos [UNESP] Bícego, Kênia C. [UNESP] Gargaglioni, Luciane H. [UNESP] da Silva, Glauber S.F. [UNESP] |
author_role |
author |
author2 |
Espinha, L.ívia P. [UNESP] Santos, Kassia M. [UNESP] Almeida, Ayla R. [UNESP] Macari, Marcos [UNESP] Bícego, Kênia C. [UNESP] Gargaglioni, Luciane H. [UNESP] da Silva, Glauber S.F. [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) National Institute of Science and Technology – Comparative Physiology (INCT- Fisiologia Comparada) Universidade Federal de Minas Gerais (UFMG) |
dc.contributor.author.fl_str_mv |
Rocha, Aline C.G. [UNESP] Espinha, L.ívia P. [UNESP] Santos, Kassia M. [UNESP] Almeida, Ayla R. [UNESP] Macari, Marcos [UNESP] Bícego, Kênia C. [UNESP] Gargaglioni, Luciane H. [UNESP] da Silva, Glauber S.F. [UNESP] |
dc.subject.por.fl_str_mv |
Arterial pressure and heart rate Body temperature Chicken embryo Chicks CO2 exposure Embryonic development Metabolic rate Pulmonary ventilation |
topic |
Arterial pressure and heart rate Body temperature Chicken embryo Chicks CO2 exposure Embryonic development Metabolic rate Pulmonary ventilation |
description |
The concentration of CO2 in the environment surrounding the embryo impacts development and may also influence the cardiorespiratory responses after hatching. Therefore, we aimed to evaluate the cardiorespiratory and thermal responses to hypercapnia in chicks that were exposed to CO2 during embryonic development, i.e., incubation. Embryos were incubated without and with a gradual increase in CO2 concentration up to 1 % during the first ten days of incubation. Ten-day-old chicks (males and females) were again acutely exposed to hypercapnia (7 % CO2), or to room air (normocapnia) and pulmonary ventilation, arterial pH and blood gases, arterial blood pressure and heart rate, body temperature (Tb) and oxygen consumption (V⋅O2) were measured. Compared to control animals, male chicks incubated with 1 % CO2 presented an attenuated ventilatory response to hypercapnia (P < 0.05), whereas no difference was found in the hypercapnic ventilatory response in both female chick groups (0 % vs 1 % CO2 incubation). Hypercapnia induced bradycardia in all groups (P < 0.001). The CO2 exposure during incubation did not alter the cardiovascular responses to hypercapnia in post-hatch animals. There were no significant effects of incubation treatment (0 % vs 1 % CO2) or sex in the mean arterial pressure, Tb, and V⋅O2 of animals in normocapnia and hypercapnia. As for the V⋅E/V⋅O2, hypercapnia caused an increase in both groups (P < 0.05), regardless of incubation treatment. In conclusion, among cardiorespiratory and metabolic variables, the ventilatory response to hypercapnia can be attenuated by pre-exposure to 1 % CO2 during embryonic development, especially in male chicks up to 10 days. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T01:44:27Z 2020-12-12T01:44:27Z 2020-02-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.resp.2019.103317 Respiratory Physiology and Neurobiology, v. 273. 1878-1519 1569-9048 http://hdl.handle.net/11449/199608 10.1016/j.resp.2019.103317 2-s2.0-85074535876 |
url |
http://dx.doi.org/10.1016/j.resp.2019.103317 http://hdl.handle.net/11449/199608 |
identifier_str_mv |
Respiratory Physiology and Neurobiology, v. 273. 1878-1519 1569-9048 10.1016/j.resp.2019.103317 2-s2.0-85074535876 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Respiratory Physiology and Neurobiology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1803045483744067584 |