Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s11239-019-02025-2 http://hdl.handle.net/11449/199911 |
Resumo: | Hallux valgus surgery (HVS) is one of the most common orthopedic procedures, often occurring in older adults. Guidelines provide inconsistent recommendations about venous thromboembolism (VTE) prophylaxis after HVS and data are scarce regarding VTE presentation and outcomes in this population. We reported the clinical characteristics and outcomes of VTE following HVS among patients enrolled in Registro Informatizado Enfermedad TromboEmbolica (RIETE), a prospective multicenter VTE registry. We compared the findings with those of other patients in RIETE. Consecutive patients with VTE post HVS were included in the study. Baseline characteristics, administration of VTE prophylaxis prior to diagnosis, presenting symptoms and signs, risk factors for VTE, and 90-day outcomes including recurrent VTE, major bleeding and death were determined. A total of 54 patients with VTE post HVS were identified in RIETE [median age: 64 (interquartile range 56–71) years; 85.2% female] and were compared with 74,111 VTE patients who had not undergone HVS. Among those with VTE post HVS, 63.0% had received VTE prophylaxis, in contrast to 35.6% in the rest of the RIETE cohort. Simplified Pulmonary Embolism Severity Index was zero in 66.7% of the patients with pulmonary embolism post HVS and 33.3% of other RIETE patients (P = 0.011). Compared with other VTE patients, use of estrogens was higher in HVS group (13.0% vs 5.4%, P = 0.01). All patients with VTE post HVS (100%) and most of other VTE patients (99.6%) were treated with anticoagulation, most commonly with low-molecular weight heparins. In contrast to the rest of the patients in RIETE, the absolute number of all fatal and non-fatal outcomes at 90 days was zero in the post HVS group (i.e. no deaths, no recurrence of VTE, and no major bleeding). In a large registry of patients with VTE, all patients with VTE post HVS underwent anticoagulation. These patients had much better outcomes than the rest of VTE patients, with no deaths, recurrences or major bleeding events at 90-day follow-up. |
id |
UNSP_2400c58282c031e8e439af4c8d59553e |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/199911 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registryBunionectomyDVTHallux valgusPEThrombosisVenous thromboembolismHallux valgus surgery (HVS) is one of the most common orthopedic procedures, often occurring in older adults. Guidelines provide inconsistent recommendations about venous thromboembolism (VTE) prophylaxis after HVS and data are scarce regarding VTE presentation and outcomes in this population. We reported the clinical characteristics and outcomes of VTE following HVS among patients enrolled in Registro Informatizado Enfermedad TromboEmbolica (RIETE), a prospective multicenter VTE registry. We compared the findings with those of other patients in RIETE. Consecutive patients with VTE post HVS were included in the study. Baseline characteristics, administration of VTE prophylaxis prior to diagnosis, presenting symptoms and signs, risk factors for VTE, and 90-day outcomes including recurrent VTE, major bleeding and death were determined. A total of 54 patients with VTE post HVS were identified in RIETE [median age: 64 (interquartile range 56–71) years; 85.2% female] and were compared with 74,111 VTE patients who had not undergone HVS. Among those with VTE post HVS, 63.0% had received VTE prophylaxis, in contrast to 35.6% in the rest of the RIETE cohort. Simplified Pulmonary Embolism Severity Index was zero in 66.7% of the patients with pulmonary embolism post HVS and 33.3% of other RIETE patients (P = 0.011). Compared with other VTE patients, use of estrogens was higher in HVS group (13.0% vs 5.4%, P = 0.01). All patients with VTE post HVS (100%) and most of other VTE patients (99.6%) were treated with anticoagulation, most commonly with low-molecular weight heparins. In contrast to the rest of the patients in RIETE, the absolute number of all fatal and non-fatal outcomes at 90 days was zero in the post HVS group (i.e. no deaths, no recurrence of VTE, and no major bleeding). In a large registry of patients with VTE, all patients with VTE post HVS underwent anticoagulation. These patients had much better outcomes than the rest of VTE patients, with no deaths, recurrences or major bleeding events at 90-day follow-up.Aged & Extended Care Services Central Adelaide Local Health Network The Queen Elizabeth Hospital, 28 Woodville Road, Woodville SouthAdelaide Geriatrics Training and Research With Aged Care (GTRAC) Centre School of Medicine Faculty of Health and Medical Science University of AdelaideDivision of Medical Subspecialties Lyell McEwin HospitalFireman Vascular Center Massachusetts General HospitalDepartment of Pneumonology Hospital Universitario ArabaDepartment of Internal Medicine Hospital General Virgen de La LuzDepartment of Internal Medicine Hospital Reina SofíaDepartment of Internal Medicine Hospital Comarcal de AxarquíaDepartment of Internal Medicine Hospital Italiano de Buenos AiresDepartment of Internal Medicine – Pulmonary Division Botucatu Medical School São Paulo State University (UNESP)Division of Cardiology Department of Medicine Columbia University Medical Center/New York-Presbyterian HospitalYale/YNHH Center for Outcomes Research & EvaluationCardiovascular Research Foundation (CRF)Hospital Universitari Germans Trias I PujolUniversidad Católica de MurciaDepartment of Internal Medicine – Pulmonary Division Botucatu Medical School São Paulo State University (UNESP)The Queen Elizabeth HospitalUniversity of AdelaideLyell McEwin HospitalMassachusetts General HospitalHospital Universitario ArabaHospital General Virgen de La LuzHospital Reina SofíaHospital Comarcal de AxarquíaHospital Italiano de Buenos AiresUniversidade Estadual Paulista (Unesp)Columbia University Medical Center/New York-Presbyterian HospitalYale/YNHH Center for Outcomes Research & EvaluationCardiovascular Research Foundation (CRF)Hospital Universitari Germans Trias I PujolUniversidad Católica de MurciaBikdeli, BavandVisvanathan, RenukaWeinberg, IdoRivas, AgustinaNieto, José AntonioSampériz, ÁngelLoring, MónicaVázquez, Fernando JavierYoo, Hugo Hyung Bok [UNESP]Bikdeli, BehnoodMonreal, Manuel2020-12-12T01:52:38Z2020-12-12T01:52:38Z2020-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article651-658http://dx.doi.org/10.1007/s11239-019-02025-2Journal of Thrombosis and Thrombolysis, v. 49, n. 4, p. 651-658, 2020.1573-742X0929-5305http://hdl.handle.net/11449/19991110.1007/s11239-019-02025-22-s2.0-85077543643Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Thrombosis and Thrombolysisinfo:eu-repo/semantics/openAccess2024-08-14T17:36:30Zoai:repositorio.unesp.br:11449/199911Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T17:36:30Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry |
title |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry |
spellingShingle |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry Bikdeli, Bavand Bunionectomy DVT Hallux valgus PE Thrombosis Venous thromboembolism |
title_short |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry |
title_full |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry |
title_fullStr |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry |
title_full_unstemmed |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry |
title_sort |
Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE registry |
author |
Bikdeli, Bavand |
author_facet |
Bikdeli, Bavand Visvanathan, Renuka Weinberg, Ido Rivas, Agustina Nieto, José Antonio Sampériz, Ángel Loring, Mónica Vázquez, Fernando Javier Yoo, Hugo Hyung Bok [UNESP] Bikdeli, Behnood Monreal, Manuel |
author_role |
author |
author2 |
Visvanathan, Renuka Weinberg, Ido Rivas, Agustina Nieto, José Antonio Sampériz, Ángel Loring, Mónica Vázquez, Fernando Javier Yoo, Hugo Hyung Bok [UNESP] Bikdeli, Behnood Monreal, Manuel |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
The Queen Elizabeth Hospital University of Adelaide Lyell McEwin Hospital Massachusetts General Hospital Hospital Universitario Araba Hospital General Virgen de La Luz Hospital Reina Sofía Hospital Comarcal de Axarquía Hospital Italiano de Buenos Aires Universidade Estadual Paulista (Unesp) Columbia University Medical Center/New York-Presbyterian Hospital Yale/YNHH Center for Outcomes Research & Evaluation Cardiovascular Research Foundation (CRF) Hospital Universitari Germans Trias I Pujol Universidad Católica de Murcia |
dc.contributor.author.fl_str_mv |
Bikdeli, Bavand Visvanathan, Renuka Weinberg, Ido Rivas, Agustina Nieto, José Antonio Sampériz, Ángel Loring, Mónica Vázquez, Fernando Javier Yoo, Hugo Hyung Bok [UNESP] Bikdeli, Behnood Monreal, Manuel |
dc.subject.por.fl_str_mv |
Bunionectomy DVT Hallux valgus PE Thrombosis Venous thromboembolism |
topic |
Bunionectomy DVT Hallux valgus PE Thrombosis Venous thromboembolism |
description |
Hallux valgus surgery (HVS) is one of the most common orthopedic procedures, often occurring in older adults. Guidelines provide inconsistent recommendations about venous thromboembolism (VTE) prophylaxis after HVS and data are scarce regarding VTE presentation and outcomes in this population. We reported the clinical characteristics and outcomes of VTE following HVS among patients enrolled in Registro Informatizado Enfermedad TromboEmbolica (RIETE), a prospective multicenter VTE registry. We compared the findings with those of other patients in RIETE. Consecutive patients with VTE post HVS were included in the study. Baseline characteristics, administration of VTE prophylaxis prior to diagnosis, presenting symptoms and signs, risk factors for VTE, and 90-day outcomes including recurrent VTE, major bleeding and death were determined. A total of 54 patients with VTE post HVS were identified in RIETE [median age: 64 (interquartile range 56–71) years; 85.2% female] and were compared with 74,111 VTE patients who had not undergone HVS. Among those with VTE post HVS, 63.0% had received VTE prophylaxis, in contrast to 35.6% in the rest of the RIETE cohort. Simplified Pulmonary Embolism Severity Index was zero in 66.7% of the patients with pulmonary embolism post HVS and 33.3% of other RIETE patients (P = 0.011). Compared with other VTE patients, use of estrogens was higher in HVS group (13.0% vs 5.4%, P = 0.01). All patients with VTE post HVS (100%) and most of other VTE patients (99.6%) were treated with anticoagulation, most commonly with low-molecular weight heparins. In contrast to the rest of the patients in RIETE, the absolute number of all fatal and non-fatal outcomes at 90 days was zero in the post HVS group (i.e. no deaths, no recurrence of VTE, and no major bleeding). In a large registry of patients with VTE, all patients with VTE post HVS underwent anticoagulation. These patients had much better outcomes than the rest of VTE patients, with no deaths, recurrences or major bleeding events at 90-day follow-up. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T01:52:38Z 2020-12-12T01:52:38Z 2020-05-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s11239-019-02025-2 Journal of Thrombosis and Thrombolysis, v. 49, n. 4, p. 651-658, 2020. 1573-742X 0929-5305 http://hdl.handle.net/11449/199911 10.1007/s11239-019-02025-2 2-s2.0-85077543643 |
url |
http://dx.doi.org/10.1007/s11239-019-02025-2 http://hdl.handle.net/11449/199911 |
identifier_str_mv |
Journal of Thrombosis and Thrombolysis, v. 49, n. 4, p. 651-658, 2020. 1573-742X 0929-5305 10.1007/s11239-019-02025-2 2-s2.0-85077543643 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Thrombosis and Thrombolysis |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
651-658 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128187828273152 |