Nanotechnology-based drug delivery systems for treatment of oral cancer: a review

Detalhes bibliográficos
Autor(a) principal: Calixto, Giovana [UNESP]
Data de Publicação: 2014
Outros Autores: Bernegossi, Jessica [UNESP], Fonseca-Santos, Bruno [UNESP], Chorilli, Marlus [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.2147/IJN.S61670
http://hdl.handle.net/11449/117454
Resumo: Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers.
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spelling Nanotechnology-based drug delivery systems for treatment of oral cancer: a reviewtargeted deliveryoral squamous cell carcinomaoral cancer treatmentOral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)PADC/FCF-UNESP (Araraquara, Brazil)Sao Paulo State Univ, UNESP, Sch Pharmaceut Sci, Dept Drugs & Pharmaceut, BR-14801902 Sao Paulo, BrazilSao Paulo State Univ, UNESP, Sch Pharmaceut Sci, Dept Drugs & Pharmaceut, BR-14801902 Sao Paulo, BrazilDove Medical Press LtdUniversidade Estadual Paulista (Unesp)Calixto, Giovana [UNESP]Bernegossi, Jessica [UNESP]Fonseca-Santos, Bruno [UNESP]Chorilli, Marlus [UNESP]2015-03-18T15:56:12Z2015-03-18T15:56:12Z2014-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article3719-3735application/pdfhttp://dx.doi.org/10.2147/IJN.S61670International Journal Of Nanomedicine. Albany: Dove Medical Press Ltd, v. 9, p. 3719-3735, 2014.1178-2013http://hdl.handle.net/11449/11745410.2147/IJN.S61670WOS:000340169100002WOS000340169100002.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal Of Nanomedicine4.3701,225info:eu-repo/semantics/openAccess2024-06-24T13:46:23Zoai:repositorio.unesp.br:11449/117454Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:00:30.952908Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
spellingShingle Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
Calixto, Giovana [UNESP]
targeted delivery
oral squamous cell carcinoma
oral cancer treatment
title_short Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_full Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_fullStr Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_full_unstemmed Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_sort Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
author Calixto, Giovana [UNESP]
author_facet Calixto, Giovana [UNESP]
Bernegossi, Jessica [UNESP]
Fonseca-Santos, Bruno [UNESP]
Chorilli, Marlus [UNESP]
author_role author
author2 Bernegossi, Jessica [UNESP]
Fonseca-Santos, Bruno [UNESP]
Chorilli, Marlus [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Calixto, Giovana [UNESP]
Bernegossi, Jessica [UNESP]
Fonseca-Santos, Bruno [UNESP]
Chorilli, Marlus [UNESP]
dc.subject.por.fl_str_mv targeted delivery
oral squamous cell carcinoma
oral cancer treatment
topic targeted delivery
oral squamous cell carcinoma
oral cancer treatment
description Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
2015-03-18T15:56:12Z
2015-03-18T15:56:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.2147/IJN.S61670
International Journal Of Nanomedicine. Albany: Dove Medical Press Ltd, v. 9, p. 3719-3735, 2014.
1178-2013
http://hdl.handle.net/11449/117454
10.2147/IJN.S61670
WOS:000340169100002
WOS000340169100002.pdf
url http://dx.doi.org/10.2147/IJN.S61670
http://hdl.handle.net/11449/117454
identifier_str_mv International Journal Of Nanomedicine. Albany: Dove Medical Press Ltd, v. 9, p. 3719-3735, 2014.
1178-2013
10.2147/IJN.S61670
WOS:000340169100002
WOS000340169100002.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal Of Nanomedicine
4.370
1,225
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 3719-3735
application/pdf
dc.publisher.none.fl_str_mv Dove Medical Press Ltd
publisher.none.fl_str_mv Dove Medical Press Ltd
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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