Queixas técnicas e eventos adversos a medicamentos notificados em um hospital sentinela do interior de São Paulo, 2009-2010

• Autor(a) principal: Lima, Paula Ferraz De
• Data de Publicação: 2013
• Outros Autores: Cavassini, Ana Claudia Molina, Silva, Flavia Aparecida Toledo, Kron, Meline Rossetto, GonÇalves, Simone Fernanda, Spadotto, Ariadne, Lima, Silvana Andréa Molina [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.5123/S1679-49742013000400014; http://hdl.handle.net/11449/136900
• topic: Pharmacovigilance; Medication Systems Hospital; Adverse Drug Reaction Reporting Systems; Drug Toxicity; Epidemiology; Descriptive.; Farmacovigilância; Sistema de Medicação no Hospital; Sistemas de Notificação de Reações Adversas a Medicamentos; Toxicidade de Drogas; Epidemiologia Descritiva.

Objective: to describe technical complaints and adverse drug events reported in a sentinel hospital in São Paulo state in 2009 and 2010. Methods: This is a descriptive study. Information was obtained from the sentinel hospital Risk Management database. Results: we found 199 reports related to drugs: 70.0% were technical complaints, 21.0% ineffective therapy and 9.0% adverse reaction to medication. The pharmacological groups with highest number of reports were: drugs that act on alimentary tract and metabolism (25.1%), the nervous system (25.1%) and anti-infective drugs for systemic use (22.1%). Conclusion: technical complaints and adverse drug events were frequent, despite recognized underreporting. The characterization of these events could inform the adoption of control measures and permanent educational actions in health services in order to prevent their occurrence.