Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/226604 |
Resumo: | The free radical scavenging capacity of Brazilian medicinal plants and some of their constituents was examined in vitro using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) quantitative assay. Twelve medicinal plants, used to treat gastrointestinal disorders (Alchornea glandulosa, Alchornea triplinervia, Anacardium humile, Byrsonima crassa, Byrsonima cinera, Byrsonima intermedia, Davilla elliptica, Davilla nitida, Mouriri pusa, Qualea grandiflora, Qualea parviflora and Qualea multiflora), were selected because they showed antiulcerogenic activity in previous studies. The radical scavenging methanolic extracts activity demonstrated to be dose-dependent. The efficient concentration, which represents the amount of the antioxidant able of decrease the initial DPPH radical by 50%, vary from < 5 to 17.2 μg/ml. The lowest efficient concentration values among the analyzed plant were shown by A. humile, B. crassa and Q. parviflora. Purified phenolic compounds (amentoflavone, (+)-catechin, methyl gallate, quercetin 3-O-alpha-L-arabinopyranoside, and quercetin 3-O-beta-D-galactopyranoside) were also tested and the greatest antioxidant activities were obtained with (+)-catechin and methyl gallate, similar to quercetin, a phenolic compound used as standard. © 2011 Academic Journals. |
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Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases2,2-diphenyl-1-picrylhydrazyl (DPPH)Antioxidant activityBrazilian medicinal plantsGastric ulcersThe free radical scavenging capacity of Brazilian medicinal plants and some of their constituents was examined in vitro using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) quantitative assay. Twelve medicinal plants, used to treat gastrointestinal disorders (Alchornea glandulosa, Alchornea triplinervia, Anacardium humile, Byrsonima crassa, Byrsonima cinera, Byrsonima intermedia, Davilla elliptica, Davilla nitida, Mouriri pusa, Qualea grandiflora, Qualea parviflora and Qualea multiflora), were selected because they showed antiulcerogenic activity in previous studies. The radical scavenging methanolic extracts activity demonstrated to be dose-dependent. The efficient concentration, which represents the amount of the antioxidant able of decrease the initial DPPH radical by 50%, vary from < 5 to 17.2 μg/ml. The lowest efficient concentration values among the analyzed plant were shown by A. humile, B. crassa and Q. parviflora. Purified phenolic compounds (amentoflavone, (+)-catechin, methyl gallate, quercetin 3-O-alpha-L-arabinopyranoside, and quercetin 3-O-beta-D-galactopyranoside) were also tested and the greatest antioxidant activities were obtained with (+)-catechin and methyl gallate, similar to quercetin, a phenolic compound used as standard. © 2011 Academic Journals.Department of Clinical Analysis School of Pharmaceutical Sciences São Paulo State University (UNESP), Araraquara, SPDepartment of Pharmaceutical Sciences Federal University of Espírito Santo (UFES), Vitória, ESSchool of Arts Sciences and Humanities University of São Paulo (USP), São Paulo, SPDepartment of Organic Chemistry Chemistry Institute São Paulo State University (UNESP), Araraquara, SPDepartment of Clinical Analysis School of Pharmaceutical Sciences São Paulo State University (UNESP), Araraquara, SPDepartment of Organic Chemistry Chemistry Institute São Paulo State University (UNESP), Araraquara, SPUniversidade Estadual Paulista (UNESP)Federal University of Espírito Santo (UFES)Universidade de São Paulo (USP)Bonacorsi, Cibele [UNESP]da Fonseca, Luiz Marcos [UNESP]Raddi, Maria Stella G. [UNESP]Kitagawa, Rodrigo R.Sannomiya, MiriamVilegas, Wagner [UNESP]2022-04-29T01:51:42Z2022-04-29T01:51:42Z2011-09-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4511-4518Journal of Medicinal Plant Research, v. 5, n. 18, p. 4511-4518, 2011.1996-0875http://hdl.handle.net/11449/2266042-s2.0-81555216095Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Medicinal Plant Researchinfo:eu-repo/semantics/openAccess2024-06-21T15:18:08Zoai:repositorio.unesp.br:11449/226604Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T13:45:22.313307Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases |
title |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases |
spellingShingle |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases Bonacorsi, Cibele [UNESP] 2,2-diphenyl-1-picrylhydrazyl (DPPH) Antioxidant activity Brazilian medicinal plants Gastric ulcers |
title_short |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases |
title_full |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases |
title_fullStr |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases |
title_full_unstemmed |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases |
title_sort |
Relative antioxidant activity of brazilian medicinal plants for gastrointestinal diseases |
author |
Bonacorsi, Cibele [UNESP] |
author_facet |
Bonacorsi, Cibele [UNESP] da Fonseca, Luiz Marcos [UNESP] Raddi, Maria Stella G. [UNESP] Kitagawa, Rodrigo R. Sannomiya, Miriam Vilegas, Wagner [UNESP] |
author_role |
author |
author2 |
da Fonseca, Luiz Marcos [UNESP] Raddi, Maria Stella G. [UNESP] Kitagawa, Rodrigo R. Sannomiya, Miriam Vilegas, Wagner [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Federal University of Espírito Santo (UFES) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Bonacorsi, Cibele [UNESP] da Fonseca, Luiz Marcos [UNESP] Raddi, Maria Stella G. [UNESP] Kitagawa, Rodrigo R. Sannomiya, Miriam Vilegas, Wagner [UNESP] |
dc.subject.por.fl_str_mv |
2,2-diphenyl-1-picrylhydrazyl (DPPH) Antioxidant activity Brazilian medicinal plants Gastric ulcers |
topic |
2,2-diphenyl-1-picrylhydrazyl (DPPH) Antioxidant activity Brazilian medicinal plants Gastric ulcers |
description |
The free radical scavenging capacity of Brazilian medicinal plants and some of their constituents was examined in vitro using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) quantitative assay. Twelve medicinal plants, used to treat gastrointestinal disorders (Alchornea glandulosa, Alchornea triplinervia, Anacardium humile, Byrsonima crassa, Byrsonima cinera, Byrsonima intermedia, Davilla elliptica, Davilla nitida, Mouriri pusa, Qualea grandiflora, Qualea parviflora and Qualea multiflora), were selected because they showed antiulcerogenic activity in previous studies. The radical scavenging methanolic extracts activity demonstrated to be dose-dependent. The efficient concentration, which represents the amount of the antioxidant able of decrease the initial DPPH radical by 50%, vary from < 5 to 17.2 μg/ml. The lowest efficient concentration values among the analyzed plant were shown by A. humile, B. crassa and Q. parviflora. Purified phenolic compounds (amentoflavone, (+)-catechin, methyl gallate, quercetin 3-O-alpha-L-arabinopyranoside, and quercetin 3-O-beta-D-galactopyranoside) were also tested and the greatest antioxidant activities were obtained with (+)-catechin and methyl gallate, similar to quercetin, a phenolic compound used as standard. © 2011 Academic Journals. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-09-16 2022-04-29T01:51:42Z 2022-04-29T01:51:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Journal of Medicinal Plant Research, v. 5, n. 18, p. 4511-4518, 2011. 1996-0875 http://hdl.handle.net/11449/226604 2-s2.0-81555216095 |
identifier_str_mv |
Journal of Medicinal Plant Research, v. 5, n. 18, p. 4511-4518, 2011. 1996-0875 2-s2.0-81555216095 |
url |
http://hdl.handle.net/11449/226604 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Medicinal Plant Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
4511-4518 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128272127492096 |