Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.gaitpost.2021.03.026 http://hdl.handle.net/11449/207507 |
Resumo: | Background: People with Multiple Sclerosis (PwMS) present higher cortical activity during walking. However, the cortical activity during gait while avoiding an obstacle is still not clear. Objective: To investigate cortical activity and gait spatial-temporal parameters in PwMS during two different gait tasks (i.e., unobstructed and obstacle avoidance). Method: Fifteen PwMS and 15 healthy controls (CG) were recruited. Participants performed ten trials in each gait condition, wearing a 64-electrode cap electroencephalogram (EEG) at 1024 Hz. Kinematic data were obtained through 10 Vicon® cameras at 200 Hz. EEG was analyzed through four cortical areas (frontal, motor, parietal, and occipital cortex areas) and five frequency bands (delta, theta, alpha, beta, and gamma) obtained through the power spectral density. In addition, spatial-temporal gait parameters (e.g., step length and velocity) were measured. Two-way ANOVA (group x gait condition) and MANOVA (group x gait condition) were used to compare gait and EEG parameters, respectively. One-way ANOVA was used to compare groups in the crossing phase of the obstacle avoidance condition. Results: PwMS presented lower step length and velocity, and higher cortical activity in frontal (beta and gamma) and parietal (gamma) cortical areas in both gait conditions compared to CG. Moreover, PwMS presented increased cortical activation (frontal and parietal) and decreased step length and velocity in obstacle avoidance compared with unobstructed gait. In addition, PwMS required more cortical resources (frontal and parietal) than CG to accomplish both gait conditions. During the obstacle avoidance task, it was further observed that PwMS positioned their feet closer to the obstacle, before and after the task, compared to CG. Conclusion: PwMS demand higher cortical resources to accomplish gait tasks, mainly when it is necessary to negotiate an obstacle in the pathway. This higher cortical activity may be a compensatory mechanism to deal with damage in subcortical structures caused by multiple sclerosis. |
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Repositório Institucional da UNESP |
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Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidanceCortical activityEEGGaitMotor controlMultiple sclerosisObstacle avoidanceBackground: People with Multiple Sclerosis (PwMS) present higher cortical activity during walking. However, the cortical activity during gait while avoiding an obstacle is still not clear. Objective: To investigate cortical activity and gait spatial-temporal parameters in PwMS during two different gait tasks (i.e., unobstructed and obstacle avoidance). Method: Fifteen PwMS and 15 healthy controls (CG) were recruited. Participants performed ten trials in each gait condition, wearing a 64-electrode cap electroencephalogram (EEG) at 1024 Hz. Kinematic data were obtained through 10 Vicon® cameras at 200 Hz. EEG was analyzed through four cortical areas (frontal, motor, parietal, and occipital cortex areas) and five frequency bands (delta, theta, alpha, beta, and gamma) obtained through the power spectral density. In addition, spatial-temporal gait parameters (e.g., step length and velocity) were measured. Two-way ANOVA (group x gait condition) and MANOVA (group x gait condition) were used to compare gait and EEG parameters, respectively. One-way ANOVA was used to compare groups in the crossing phase of the obstacle avoidance condition. Results: PwMS presented lower step length and velocity, and higher cortical activity in frontal (beta and gamma) and parietal (gamma) cortical areas in both gait conditions compared to CG. Moreover, PwMS presented increased cortical activation (frontal and parietal) and decreased step length and velocity in obstacle avoidance compared with unobstructed gait. In addition, PwMS required more cortical resources (frontal and parietal) than CG to accomplish both gait conditions. During the obstacle avoidance task, it was further observed that PwMS positioned their feet closer to the obstacle, before and after the task, compared to CG. Conclusion: PwMS demand higher cortical resources to accomplish gait tasks, mainly when it is necessary to negotiate an obstacle in the pathway. This higher cortical activity may be a compensatory mechanism to deal with damage in subcortical structures caused by multiple sclerosis.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)São Paulo State University (UNESP) – Campus Bauru School of Science Human Movement Research Laboratory (MOVI-LAB) Department of Physical Education Graduate Program in Movement ScienceDepartment of Kinesiology and Physical Education Northern Illinois UniversitySão Paulo State University (UNESP) – Campus Bauru School of Science Human Movement Research Laboratory (MOVI-LAB) Department of Physical Education Graduate Program in Movement ScienceUniversidade Estadual Paulista (Unesp)Northern Illinois UniversitySantinelli, Felipe Balistieri [UNESP]Sebastião, EmersonKuroda, Marina Hiromi [UNESP]Moreno, Vinicius Christianini [UNESP]Pilon, Julia [UNESP]Vieira, Luiz Henrique Palucci [UNESP]Barbieri, Fabio Augusto [UNESP]2021-06-25T10:56:24Z2021-06-25T10:56:24Z2021-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article226-232http://dx.doi.org/10.1016/j.gaitpost.2021.03.026Gait and Posture, v. 86, p. 226-232.1879-22190966-6362http://hdl.handle.net/11449/20750710.1016/j.gaitpost.2021.03.0262-s2.0-85103076947Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengGait and Postureinfo:eu-repo/semantics/openAccess2024-04-24T18:53:10Zoai:repositorio.unesp.br:11449/207507Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-04-24T18:53:10Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance |
title |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance |
spellingShingle |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance Santinelli, Felipe Balistieri [UNESP] Cortical activity EEG Gait Motor control Multiple sclerosis Obstacle avoidance |
title_short |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance |
title_full |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance |
title_fullStr |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance |
title_full_unstemmed |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance |
title_sort |
Cortical activity and gait parameter characteristics in people with multiple sclerosis during unobstructed gait and obstacle avoidance |
author |
Santinelli, Felipe Balistieri [UNESP] |
author_facet |
Santinelli, Felipe Balistieri [UNESP] Sebastião, Emerson Kuroda, Marina Hiromi [UNESP] Moreno, Vinicius Christianini [UNESP] Pilon, Julia [UNESP] Vieira, Luiz Henrique Palucci [UNESP] Barbieri, Fabio Augusto [UNESP] |
author_role |
author |
author2 |
Sebastião, Emerson Kuroda, Marina Hiromi [UNESP] Moreno, Vinicius Christianini [UNESP] Pilon, Julia [UNESP] Vieira, Luiz Henrique Palucci [UNESP] Barbieri, Fabio Augusto [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Northern Illinois University |
dc.contributor.author.fl_str_mv |
Santinelli, Felipe Balistieri [UNESP] Sebastião, Emerson Kuroda, Marina Hiromi [UNESP] Moreno, Vinicius Christianini [UNESP] Pilon, Julia [UNESP] Vieira, Luiz Henrique Palucci [UNESP] Barbieri, Fabio Augusto [UNESP] |
dc.subject.por.fl_str_mv |
Cortical activity EEG Gait Motor control Multiple sclerosis Obstacle avoidance |
topic |
Cortical activity EEG Gait Motor control Multiple sclerosis Obstacle avoidance |
description |
Background: People with Multiple Sclerosis (PwMS) present higher cortical activity during walking. However, the cortical activity during gait while avoiding an obstacle is still not clear. Objective: To investigate cortical activity and gait spatial-temporal parameters in PwMS during two different gait tasks (i.e., unobstructed and obstacle avoidance). Method: Fifteen PwMS and 15 healthy controls (CG) were recruited. Participants performed ten trials in each gait condition, wearing a 64-electrode cap electroencephalogram (EEG) at 1024 Hz. Kinematic data were obtained through 10 Vicon® cameras at 200 Hz. EEG was analyzed through four cortical areas (frontal, motor, parietal, and occipital cortex areas) and five frequency bands (delta, theta, alpha, beta, and gamma) obtained through the power spectral density. In addition, spatial-temporal gait parameters (e.g., step length and velocity) were measured. Two-way ANOVA (group x gait condition) and MANOVA (group x gait condition) were used to compare gait and EEG parameters, respectively. One-way ANOVA was used to compare groups in the crossing phase of the obstacle avoidance condition. Results: PwMS presented lower step length and velocity, and higher cortical activity in frontal (beta and gamma) and parietal (gamma) cortical areas in both gait conditions compared to CG. Moreover, PwMS presented increased cortical activation (frontal and parietal) and decreased step length and velocity in obstacle avoidance compared with unobstructed gait. In addition, PwMS required more cortical resources (frontal and parietal) than CG to accomplish both gait conditions. During the obstacle avoidance task, it was further observed that PwMS positioned their feet closer to the obstacle, before and after the task, compared to CG. Conclusion: PwMS demand higher cortical resources to accomplish gait tasks, mainly when it is necessary to negotiate an obstacle in the pathway. This higher cortical activity may be a compensatory mechanism to deal with damage in subcortical structures caused by multiple sclerosis. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T10:56:24Z 2021-06-25T10:56:24Z 2021-05-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.gaitpost.2021.03.026 Gait and Posture, v. 86, p. 226-232. 1879-2219 0966-6362 http://hdl.handle.net/11449/207507 10.1016/j.gaitpost.2021.03.026 2-s2.0-85103076947 |
url |
http://dx.doi.org/10.1016/j.gaitpost.2021.03.026 http://hdl.handle.net/11449/207507 |
identifier_str_mv |
Gait and Posture, v. 86, p. 226-232. 1879-2219 0966-6362 10.1016/j.gaitpost.2021.03.026 2-s2.0-85103076947 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Gait and Posture |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
226-232 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803046431092637696 |