Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.4067/S0717-95022009000300045 http://hdl.handle.net/11449/6746 |
Resumo: | The neuromuscular junction of the extensor digitorum longus muscle of fingers was analyzed in 21 young (three months) and old (from six to 25 months) mice, from both genders. Morphologic changes were found throughout the mouse life, being more frequent and visible with aging. According with the data described in the literature consulted and the observations taken in this research, it becomes clear that a continuous process of morphological remodeling occurs in all neuromuscular ultrastructural junctions of the extensor digitorum longus muscle of fingers, during the life of the animal. Theses changes are characterized by figures of myelin in the cytoplasm of Schwann cells, pleomorphic and multivesiclar bodies, mitochondrias with morphologically altered crests in the axon terminal and degenerated junction folders. Coated vesicles are common in older animals and rare in young animals. |
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Repositório Institucional da UNESP |
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Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the MiceNeuromuscular junctionsMiceUltrastructureExtensor digitorum longus muscleThe neuromuscular junction of the extensor digitorum longus muscle of fingers was analyzed in 21 young (three months) and old (from six to 25 months) mice, from both genders. Morphologic changes were found throughout the mouse life, being more frequent and visible with aging. According with the data described in the literature consulted and the observations taken in this research, it becomes clear that a continuous process of morphological remodeling occurs in all neuromuscular ultrastructural junctions of the extensor digitorum longus muscle of fingers, during the life of the animal. Theses changes are characterized by figures of myelin in the cytoplasm of Schwann cells, pleomorphic and multivesiclar bodies, mitochondrias with morphologically altered crests in the axon terminal and degenerated junction folders. Coated vesicles are common in older animals and rare in young animals.São Paulo State Univ Julio de Mesquita Filho, UNESP, Dept Phys Educ, Fac Ciencias & Tecnol, BR-19060900 Presidente Prudente, SP, BrazilSão Paulo State Univ Julio de Mesquita Filho, UNESP, Dept Physiotherapy, Fac Ciencias & Tecnol, BR-19060900 Presidente Prudente, SP, BrazilSão Paulo State Univ Julio de Mesquita Filho, UNESP, Dept Phys Educ, Fac Ciencias & Tecnol, BR-19060900 Presidente Prudente, SP, BrazilSão Paulo State Univ Julio de Mesquita Filho, UNESP, Dept Physiotherapy, Fac Ciencias & Tecnol, BR-19060900 Presidente Prudente, SP, BrazilSoc Chilena AnatomiaUniversidade Estadual Paulista (Unesp)Boaro, Sueli N. [UNESP]Fragoso Neto, Raul Antonio [UNESP]2014-05-20T13:22:49Z2014-05-20T13:22:49Z2009-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article927-932application/pdfhttp://dx.doi.org/10.4067/S0717-95022009000300045International Journal of Morphology. Temuco: Soc Chilena Anatomia, v. 27, n. 3, p. 927-932, 2009.http://hdl.handle.net/11449/6746WOS:000275947100044WOS000275947100044.pdf90003030095457120000-0001-6052-2626Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Morphologyinfo:eu-repo/semantics/openAccess2024-06-18T18:44:02Zoai:repositorio.unesp.br:11449/6746Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:25:26.484226Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice |
title |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice |
spellingShingle |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice Boaro, Sueli N. [UNESP] Neuromuscular junctions Mice Ultrastructure Extensor digitorum longus muscle |
title_short |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice |
title_full |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice |
title_fullStr |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice |
title_full_unstemmed |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice |
title_sort |
Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice |
author |
Boaro, Sueli N. [UNESP] |
author_facet |
Boaro, Sueli N. [UNESP] Fragoso Neto, Raul Antonio [UNESP] |
author_role |
author |
author2 |
Fragoso Neto, Raul Antonio [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Boaro, Sueli N. [UNESP] Fragoso Neto, Raul Antonio [UNESP] |
dc.subject.por.fl_str_mv |
Neuromuscular junctions Mice Ultrastructure Extensor digitorum longus muscle |
topic |
Neuromuscular junctions Mice Ultrastructure Extensor digitorum longus muscle |
description |
The neuromuscular junction of the extensor digitorum longus muscle of fingers was analyzed in 21 young (three months) and old (from six to 25 months) mice, from both genders. Morphologic changes were found throughout the mouse life, being more frequent and visible with aging. According with the data described in the literature consulted and the observations taken in this research, it becomes clear that a continuous process of morphological remodeling occurs in all neuromuscular ultrastructural junctions of the extensor digitorum longus muscle of fingers, during the life of the animal. Theses changes are characterized by figures of myelin in the cytoplasm of Schwann cells, pleomorphic and multivesiclar bodies, mitochondrias with morphologically altered crests in the axon terminal and degenerated junction folders. Coated vesicles are common in older animals and rare in young animals. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-09-01 2014-05-20T13:22:49Z 2014-05-20T13:22:49Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4067/S0717-95022009000300045 International Journal of Morphology. Temuco: Soc Chilena Anatomia, v. 27, n. 3, p. 927-932, 2009. http://hdl.handle.net/11449/6746 WOS:000275947100044 WOS000275947100044.pdf 9000303009545712 0000-0001-6052-2626 |
url |
http://dx.doi.org/10.4067/S0717-95022009000300045 http://hdl.handle.net/11449/6746 |
identifier_str_mv |
International Journal of Morphology. Temuco: Soc Chilena Anatomia, v. 27, n. 3, p. 927-932, 2009. WOS:000275947100044 WOS000275947100044.pdf 9000303009545712 0000-0001-6052-2626 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Journal of Morphology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
927-932 application/pdf |
dc.publisher.none.fl_str_mv |
Soc Chilena Anatomia |
publisher.none.fl_str_mv |
Soc Chilena Anatomia |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128930476982272 |