Are Brazilian cervids at risk of prion diseases?
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1080/19336896.2016.1274000 http://hdl.handle.net/11449/159423 |
Resumo: | Prion diseases are neurodegenerative fatal disorders that affect human and non-human mammals. Chronic Wasting Disease (CWD) is a prion disease of cervids regarded as a public health problem in North America, and polymorphisms at specific codons in the PRNP gene are associated with this disease. To assess the potential CWD susceptibility of South American free-ranging deer, the presence of these polymorphisms was examined in Mazama gouazoubira, Ozotoceros bezoarticus and Blastocerus dichotomus. Despite the lack of CWD reports in Brazil, the examined codons (95, 96, 116, 132, 225, and 226) of the PRNP gene showed potential CWD susceptibility in Brazilian deer. Low abundancy of deer in Brazil possibly difficult both CWD proliferation and detection, however, CWD surveillance may not be neglected. |
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Are Brazilian cervids at risk of prion diseases?Blastoceruschronic wasting diseaseMazamaneotropical deerOzotocerusPrPprionPrion diseases are neurodegenerative fatal disorders that affect human and non-human mammals. Chronic Wasting Disease (CWD) is a prion disease of cervids regarded as a public health problem in North America, and polymorphisms at specific codons in the PRNP gene are associated with this disease. To assess the potential CWD susceptibility of South American free-ranging deer, the presence of these polymorphisms was examined in Mazama gouazoubira, Ozotoceros bezoarticus and Blastocerus dichotomus. Despite the lack of CWD reports in Brazil, the examined codons (95, 96, 116, 132, 225, and 226) of the PRNP gene showed potential CWD susceptibility in Brazilian deer. Low abundancy of deer in Brazil possibly difficult both CWD proliferation and detection, however, CWD surveillance may not be neglected.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)FACEPE (Fundacao de Amparo a Ciencia e Tecnologia de Pernambuco)Univ Fed Pernambuco, Ctr Acad Vitoria, Vitoria De Santo Antao, PE, BrazilUniv Estadual Paulista, Dept Zootecnia, Sao Paulo, BrazilUniv Fed Pernambuco, Dept Neuropsiquiatria, Recife, PE, BrazilUniv Fed Pernambuco, Dept Zool, Recife, PE, BrazilUniv Estadual Paulista, Dept Zootecnia, Sao Paulo, BrazilCNPq: 480959/2011-0Taylor & Francis IncUniversidade Federal de Pernambuco (UFPE)Universidade Estadual Paulista (Unesp)Ribeiro Falcao, Caio BrunoNunes Freire Lima, Isabel Luiza de MeloBarbanti Duarte, Jose Mauricio [UNESP]Mendes de Oliveira, Joao RicardoTorres, Rodrigo AugustoWanderley, Artur MaiaGomes da Cunha, Jose EritonGarcia, Jose Eduardo2018-11-26T15:43:43Z2018-11-26T15:43:43Z2017-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article65-70application/pdfhttp://dx.doi.org/10.1080/19336896.2016.1274000Prion. Philadelphia: Taylor & Francis Inc, v. 11, n. 1, p. 65-70, 2017.1933-6896http://hdl.handle.net/11449/15942310.1080/19336896.2016.1274000WOS:000396024200008WOS000396024200008.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPrion1,081info:eu-repo/semantics/openAccess2023-11-30T06:14:30Zoai:repositorio.unesp.br:11449/159423Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:08:06.992090Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Are Brazilian cervids at risk of prion diseases? |
title |
Are Brazilian cervids at risk of prion diseases? |
spellingShingle |
Are Brazilian cervids at risk of prion diseases? Ribeiro Falcao, Caio Bruno Blastocerus chronic wasting disease Mazama neotropical deer Ozotocerus PrP prion |
title_short |
Are Brazilian cervids at risk of prion diseases? |
title_full |
Are Brazilian cervids at risk of prion diseases? |
title_fullStr |
Are Brazilian cervids at risk of prion diseases? |
title_full_unstemmed |
Are Brazilian cervids at risk of prion diseases? |
title_sort |
Are Brazilian cervids at risk of prion diseases? |
author |
Ribeiro Falcao, Caio Bruno |
author_facet |
Ribeiro Falcao, Caio Bruno Nunes Freire Lima, Isabel Luiza de Melo Barbanti Duarte, Jose Mauricio [UNESP] Mendes de Oliveira, Joao Ricardo Torres, Rodrigo Augusto Wanderley, Artur Maia Gomes da Cunha, Jose Eriton Garcia, Jose Eduardo |
author_role |
author |
author2 |
Nunes Freire Lima, Isabel Luiza de Melo Barbanti Duarte, Jose Mauricio [UNESP] Mendes de Oliveira, Joao Ricardo Torres, Rodrigo Augusto Wanderley, Artur Maia Gomes da Cunha, Jose Eriton Garcia, Jose Eduardo |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de Pernambuco (UFPE) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Ribeiro Falcao, Caio Bruno Nunes Freire Lima, Isabel Luiza de Melo Barbanti Duarte, Jose Mauricio [UNESP] Mendes de Oliveira, Joao Ricardo Torres, Rodrigo Augusto Wanderley, Artur Maia Gomes da Cunha, Jose Eriton Garcia, Jose Eduardo |
dc.subject.por.fl_str_mv |
Blastocerus chronic wasting disease Mazama neotropical deer Ozotocerus PrP prion |
topic |
Blastocerus chronic wasting disease Mazama neotropical deer Ozotocerus PrP prion |
description |
Prion diseases are neurodegenerative fatal disorders that affect human and non-human mammals. Chronic Wasting Disease (CWD) is a prion disease of cervids regarded as a public health problem in North America, and polymorphisms at specific codons in the PRNP gene are associated with this disease. To assess the potential CWD susceptibility of South American free-ranging deer, the presence of these polymorphisms was examined in Mazama gouazoubira, Ozotoceros bezoarticus and Blastocerus dichotomus. Despite the lack of CWD reports in Brazil, the examined codons (95, 96, 116, 132, 225, and 226) of the PRNP gene showed potential CWD susceptibility in Brazilian deer. Low abundancy of deer in Brazil possibly difficult both CWD proliferation and detection, however, CWD surveillance may not be neglected. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 2018-11-26T15:43:43Z 2018-11-26T15:43:43Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1080/19336896.2016.1274000 Prion. Philadelphia: Taylor & Francis Inc, v. 11, n. 1, p. 65-70, 2017. 1933-6896 http://hdl.handle.net/11449/159423 10.1080/19336896.2016.1274000 WOS:000396024200008 WOS000396024200008.pdf |
url |
http://dx.doi.org/10.1080/19336896.2016.1274000 http://hdl.handle.net/11449/159423 |
identifier_str_mv |
Prion. Philadelphia: Taylor & Francis Inc, v. 11, n. 1, p. 65-70, 2017. 1933-6896 10.1080/19336896.2016.1274000 WOS:000396024200008 WOS000396024200008.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Prion 1,081 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
65-70 application/pdf |
dc.publisher.none.fl_str_mv |
Taylor & Francis Inc |
publisher.none.fl_str_mv |
Taylor & Francis Inc |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129023179489280 |