Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial

Detalhes bibliográficos
Autor(a) principal: Bonardi, João Paulo [UNESP]
Data de Publicação: 2023
Outros Autores: Pereira, Rodrigo dos Santos, Mourão, Carlos F., Coelho Mendes, Bruno [UNESP], Lowenstein, Adam, Montemezzi, Pietro, Giubilato, Flavio [UNESP], Okamoto, Roberta [UNESP], Hochuli-Vieira, Eduardo [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3390/ma16031059
http://hdl.handle.net/11449/248357
Resumo: The aim of the present study is to compare the biphasic calcium phosphate (BCP) using two different forms—(1) granules and (2) paste—in human maxillary sinus bone reconstruction as a split-mouth study using histomorphometric and immunolabeling for osteocalcin. Ten patients with bilateral maxillary posterior partial edentulism were selected in order to reconstruct bone height. They were divided into two groups: BCPG and BCP-P. After six months of bone healing, biopsies were harvested to assess the new bone formation and immunostaining for osteocalcin. The BCP g group had the following results: mean of bone formation in pristine bone 49.4 ± 21.6%, intermediate 49.4 ± 16.2%, and apical 55.3 ± 21.4%. The group BCP-P had a mean of 41.9 ± 17.3% in the pristine bone region, 37.5 ± 7.8% for intermediate, and 39.0 ± 13.5% for apical. The osteocalcin immunolabeling was high for both groups, demonstrating bone calcification. Thus, the two biomaterials present suitable results for the placement of dental implants.
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spelling Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trialbiomaterialsbone substitutessinus floor augmentationThe aim of the present study is to compare the biphasic calcium phosphate (BCP) using two different forms—(1) granules and (2) paste—in human maxillary sinus bone reconstruction as a split-mouth study using histomorphometric and immunolabeling for osteocalcin. Ten patients with bilateral maxillary posterior partial edentulism were selected in order to reconstruct bone height. They were divided into two groups: BCPG and BCP-P. After six months of bone healing, biopsies were harvested to assess the new bone formation and immunostaining for osteocalcin. The BCP g group had the following results: mean of bone formation in pristine bone 49.4 ± 21.6%, intermediate 49.4 ± 16.2%, and apical 55.3 ± 21.4%. The group BCP-P had a mean of 41.9 ± 17.3% in the pristine bone region, 37.5 ± 7.8% for intermediate, and 39.0 ± 13.5% for apical. The osteocalcin immunolabeling was high for both groups, demonstrating bone calcification. Thus, the two biomaterials present suitable results for the placement of dental implants.Department of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Oral & Maxillofacial Surgery University of Grande Rio-UNIGRANRIODepartment of Periodontology Division of Dental Research Administration Tufts University School of Dental MedicineDepartment of Dentistry San Raffaele HospitalDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Diagnostic and Surgery Araraquara School of Dentistry Sao Paulo State UniversityDepartment of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Diagnostic and Surgery Araraquara School of Dentistry Sao Paulo State UniversityUniversidade Estadual Paulista (UNESP)University of Grande Rio-UNIGRANRIOTufts University School of Dental MedicineSan Raffaele HospitalBonardi, João Paulo [UNESP]Pereira, Rodrigo dos SantosMourão, Carlos F.Coelho Mendes, Bruno [UNESP]Lowenstein, AdamMontemezzi, PietroGiubilato, Flavio [UNESP]Okamoto, Roberta [UNESP]Hochuli-Vieira, Eduardo [UNESP]2023-07-29T13:41:44Z2023-07-29T13:41:44Z2023-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/ma16031059Materials, v. 16, n. 3, 2023.1996-1944http://hdl.handle.net/11449/24835710.3390/ma160310592-s2.0-85148046032Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterialsinfo:eu-repo/semantics/openAccess2024-09-26T15:21:38Zoai:repositorio.unesp.br:11449/248357Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-26T15:21:38Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
title Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
spellingShingle Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
Bonardi, João Paulo [UNESP]
biomaterials
bone substitutes
sinus floor augmentation
title_short Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
title_full Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
title_fullStr Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
title_full_unstemmed Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
title_sort Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
author Bonardi, João Paulo [UNESP]
author_facet Bonardi, João Paulo [UNESP]
Pereira, Rodrigo dos Santos
Mourão, Carlos F.
Coelho Mendes, Bruno [UNESP]
Lowenstein, Adam
Montemezzi, Pietro
Giubilato, Flavio [UNESP]
Okamoto, Roberta [UNESP]
Hochuli-Vieira, Eduardo [UNESP]
author_role author
author2 Pereira, Rodrigo dos Santos
Mourão, Carlos F.
Coelho Mendes, Bruno [UNESP]
Lowenstein, Adam
Montemezzi, Pietro
Giubilato, Flavio [UNESP]
Okamoto, Roberta [UNESP]
Hochuli-Vieira, Eduardo [UNESP]
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
University of Grande Rio-UNIGRANRIO
Tufts University School of Dental Medicine
San Raffaele Hospital
dc.contributor.author.fl_str_mv Bonardi, João Paulo [UNESP]
Pereira, Rodrigo dos Santos
Mourão, Carlos F.
Coelho Mendes, Bruno [UNESP]
Lowenstein, Adam
Montemezzi, Pietro
Giubilato, Flavio [UNESP]
Okamoto, Roberta [UNESP]
Hochuli-Vieira, Eduardo [UNESP]
dc.subject.por.fl_str_mv biomaterials
bone substitutes
sinus floor augmentation
topic biomaterials
bone substitutes
sinus floor augmentation
description The aim of the present study is to compare the biphasic calcium phosphate (BCP) using two different forms—(1) granules and (2) paste—in human maxillary sinus bone reconstruction as a split-mouth study using histomorphometric and immunolabeling for osteocalcin. Ten patients with bilateral maxillary posterior partial edentulism were selected in order to reconstruct bone height. They were divided into two groups: BCPG and BCP-P. After six months of bone healing, biopsies were harvested to assess the new bone formation and immunostaining for osteocalcin. The BCP g group had the following results: mean of bone formation in pristine bone 49.4 ± 21.6%, intermediate 49.4 ± 16.2%, and apical 55.3 ± 21.4%. The group BCP-P had a mean of 41.9 ± 17.3% in the pristine bone region, 37.5 ± 7.8% for intermediate, and 39.0 ± 13.5% for apical. The osteocalcin immunolabeling was high for both groups, demonstrating bone calcification. Thus, the two biomaterials present suitable results for the placement of dental implants.
publishDate 2023
dc.date.none.fl_str_mv 2023-07-29T13:41:44Z
2023-07-29T13:41:44Z
2023-02-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3390/ma16031059
Materials, v. 16, n. 3, 2023.
1996-1944
http://hdl.handle.net/11449/248357
10.3390/ma16031059
2-s2.0-85148046032
url http://dx.doi.org/10.3390/ma16031059
http://hdl.handle.net/11449/248357
identifier_str_mv Materials, v. 16, n. 3, 2023.
1996-1944
10.3390/ma16031059
2-s2.0-85148046032
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Materials
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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