Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/ma16031059 http://hdl.handle.net/11449/248357 |
Resumo: | The aim of the present study is to compare the biphasic calcium phosphate (BCP) using two different forms—(1) granules and (2) paste—in human maxillary sinus bone reconstruction as a split-mouth study using histomorphometric and immunolabeling for osteocalcin. Ten patients with bilateral maxillary posterior partial edentulism were selected in order to reconstruct bone height. They were divided into two groups: BCPG and BCP-P. After six months of bone healing, biopsies were harvested to assess the new bone formation and immunostaining for osteocalcin. The BCP g group had the following results: mean of bone formation in pristine bone 49.4 ± 21.6%, intermediate 49.4 ± 16.2%, and apical 55.3 ± 21.4%. The group BCP-P had a mean of 41.9 ± 17.3% in the pristine bone region, 37.5 ± 7.8% for intermediate, and 39.0 ± 13.5% for apical. The osteocalcin immunolabeling was high for both groups, demonstrating bone calcification. Thus, the two biomaterials present suitable results for the placement of dental implants. |
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Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trialbiomaterialsbone substitutessinus floor augmentationThe aim of the present study is to compare the biphasic calcium phosphate (BCP) using two different forms—(1) granules and (2) paste—in human maxillary sinus bone reconstruction as a split-mouth study using histomorphometric and immunolabeling for osteocalcin. Ten patients with bilateral maxillary posterior partial edentulism were selected in order to reconstruct bone height. They were divided into two groups: BCPG and BCP-P. After six months of bone healing, biopsies were harvested to assess the new bone formation and immunostaining for osteocalcin. The BCP g group had the following results: mean of bone formation in pristine bone 49.4 ± 21.6%, intermediate 49.4 ± 16.2%, and apical 55.3 ± 21.4%. The group BCP-P had a mean of 41.9 ± 17.3% in the pristine bone region, 37.5 ± 7.8% for intermediate, and 39.0 ± 13.5% for apical. The osteocalcin immunolabeling was high for both groups, demonstrating bone calcification. Thus, the two biomaterials present suitable results for the placement of dental implants.Department of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Oral & Maxillofacial Surgery University of Grande Rio-UNIGRANRIODepartment of Periodontology Division of Dental Research Administration Tufts University School of Dental MedicineDepartment of Dentistry San Raffaele HospitalDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Diagnostic and Surgery Araraquara School of Dentistry Sao Paulo State UniversityDepartment of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State UniversityDepartment of Diagnostic and Surgery Araraquara School of Dentistry Sao Paulo State UniversityUniversidade Estadual Paulista (UNESP)University of Grande Rio-UNIGRANRIOTufts University School of Dental MedicineSan Raffaele HospitalBonardi, João Paulo [UNESP]Pereira, Rodrigo dos SantosMourão, Carlos F.Coelho Mendes, Bruno [UNESP]Lowenstein, AdamMontemezzi, PietroGiubilato, Flavio [UNESP]Okamoto, Roberta [UNESP]Hochuli-Vieira, Eduardo [UNESP]2023-07-29T13:41:44Z2023-07-29T13:41:44Z2023-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/ma16031059Materials, v. 16, n. 3, 2023.1996-1944http://hdl.handle.net/11449/24835710.3390/ma160310592-s2.0-85148046032Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterialsinfo:eu-repo/semantics/openAccess2024-09-26T15:21:38Zoai:repositorio.unesp.br:11449/248357Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-26T15:21:38Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial |
title |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial |
spellingShingle |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial Bonardi, João Paulo [UNESP] biomaterials bone substitutes sinus floor augmentation |
title_short |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial |
title_full |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial |
title_fullStr |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial |
title_full_unstemmed |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial |
title_sort |
Clinical Assessment of Biphasic Calcium Phosphate in Granules and Paste Forms in Human Maxillary Sinus Bone Augmentation: A Randomized, Split-Mouth Clinical Trial |
author |
Bonardi, João Paulo [UNESP] |
author_facet |
Bonardi, João Paulo [UNESP] Pereira, Rodrigo dos Santos Mourão, Carlos F. Coelho Mendes, Bruno [UNESP] Lowenstein, Adam Montemezzi, Pietro Giubilato, Flavio [UNESP] Okamoto, Roberta [UNESP] Hochuli-Vieira, Eduardo [UNESP] |
author_role |
author |
author2 |
Pereira, Rodrigo dos Santos Mourão, Carlos F. Coelho Mendes, Bruno [UNESP] Lowenstein, Adam Montemezzi, Pietro Giubilato, Flavio [UNESP] Okamoto, Roberta [UNESP] Hochuli-Vieira, Eduardo [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) University of Grande Rio-UNIGRANRIO Tufts University School of Dental Medicine San Raffaele Hospital |
dc.contributor.author.fl_str_mv |
Bonardi, João Paulo [UNESP] Pereira, Rodrigo dos Santos Mourão, Carlos F. Coelho Mendes, Bruno [UNESP] Lowenstein, Adam Montemezzi, Pietro Giubilato, Flavio [UNESP] Okamoto, Roberta [UNESP] Hochuli-Vieira, Eduardo [UNESP] |
dc.subject.por.fl_str_mv |
biomaterials bone substitutes sinus floor augmentation |
topic |
biomaterials bone substitutes sinus floor augmentation |
description |
The aim of the present study is to compare the biphasic calcium phosphate (BCP) using two different forms—(1) granules and (2) paste—in human maxillary sinus bone reconstruction as a split-mouth study using histomorphometric and immunolabeling for osteocalcin. Ten patients with bilateral maxillary posterior partial edentulism were selected in order to reconstruct bone height. They were divided into two groups: BCPG and BCP-P. After six months of bone healing, biopsies were harvested to assess the new bone formation and immunostaining for osteocalcin. The BCP g group had the following results: mean of bone formation in pristine bone 49.4 ± 21.6%, intermediate 49.4 ± 16.2%, and apical 55.3 ± 21.4%. The group BCP-P had a mean of 41.9 ± 17.3% in the pristine bone region, 37.5 ± 7.8% for intermediate, and 39.0 ± 13.5% for apical. The osteocalcin immunolabeling was high for both groups, demonstrating bone calcification. Thus, the two biomaterials present suitable results for the placement of dental implants. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T13:41:44Z 2023-07-29T13:41:44Z 2023-02-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/ma16031059 Materials, v. 16, n. 3, 2023. 1996-1944 http://hdl.handle.net/11449/248357 10.3390/ma16031059 2-s2.0-85148046032 |
url |
http://dx.doi.org/10.3390/ma16031059 http://hdl.handle.net/11449/248357 |
identifier_str_mv |
Materials, v. 16, n. 3, 2023. 1996-1944 10.3390/ma16031059 2-s2.0-85148046032 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Materials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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1813546445896155137 |