Analysis of risk factors and postoperative complications in patients with crohn’s disease

Detalhes bibliográficos
Autor(a) principal: Saad Hossne, Rogério [UNESP]
Data de Publicação: 2018
Outros Autores: Sassaki, Ligia Yukie [UNESP], Baima, Julio Pinheiro [UNESP], de Meira JÚnior, José Donizeti [UNESP], Campos, Luana Moraes [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/s0004-2803.201800000-63
http://hdl.handle.net/11449/188492
Resumo: Background – The post-operative complications rate is greater in patients with Crohn’s disease than in other abdominal surgeries due to other benign conditions. Prevention and management of such complications are important factors in the care of these patients. Objective – The objectives of this research are to analyze the rate of postoperative complications and the major risk factors in patients with Crohn’s disease. Methods – A descriptive and retrospective study based on analysis of medical records of patients with Crohn’s disease undergoing ileal and/or colonic resection, which analyzed the main surgical complications and their major risk factors. Results – Forty-four surgical procedures and thirty-seven patients were analyzed. Most were female (56.7%). Postoperative complications were observed in 18 (40.9%) surgeries. The disease duration (P=0.04), the penetrating behavior (P=0.013), the time between diagnosis and the first surgery (P=0.04), malnutrition with low body mass index (BMI), duration of surgery (P=0.016), and the size of the removed specimen (P=0.014) were associated with higher rates of complications. The use of drugs blocking tumor necrosis factor up to eight weeks before surgery was not significantly associated with higher complications rates or increased need for reoperation. Conclusion – The complication rate observed in this study is similar to published data. The duration of the disease, the penetrating behavior, the size of the removed specimen, the duration of the surgery, and BMI are important risk factors for perioperative complications in Crohn’s disease.
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spelling Analysis of risk factors and postoperative complications in patients with crohn’s diseaseAnálise dos fatores de risco e complicações pós-operatórias em pacientes portadores de doença de crohnDigestive system surgical proceduresInflammatory bowel diseasePostoperative complicationsRisk factorsSecondary preventionBackground – The post-operative complications rate is greater in patients with Crohn’s disease than in other abdominal surgeries due to other benign conditions. Prevention and management of such complications are important factors in the care of these patients. Objective – The objectives of this research are to analyze the rate of postoperative complications and the major risk factors in patients with Crohn’s disease. Methods – A descriptive and retrospective study based on analysis of medical records of patients with Crohn’s disease undergoing ileal and/or colonic resection, which analyzed the main surgical complications and their major risk factors. Results – Forty-four surgical procedures and thirty-seven patients were analyzed. Most were female (56.7%). Postoperative complications were observed in 18 (40.9%) surgeries. The disease duration (P=0.04), the penetrating behavior (P=0.013), the time between diagnosis and the first surgery (P=0.04), malnutrition with low body mass index (BMI), duration of surgery (P=0.016), and the size of the removed specimen (P=0.014) were associated with higher rates of complications. The use of drugs blocking tumor necrosis factor up to eight weeks before surgery was not significantly associated with higher complications rates or increased need for reoperation. Conclusion – The complication rate observed in this study is similar to published data. The duration of the disease, the penetrating behavior, the size of the removed specimen, the duration of the surgery, and BMI are important risk factors for perioperative complications in Crohn’s disease.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista (UNESP) Faculdade de Medicina Departamento de Cirurgia e OrtopediaUniversidade Estadual Paulista (UNESP) Faculdade de Medicina Departamento de Clínica MédicaUniversidade Estadual Paulista (UNESP) Faculdade de Medicina Departamento de Cirurgia e OrtopediaUniversidade Estadual Paulista (UNESP) Faculdade de Medicina Departamento de Clínica MédicaUniversidade Estadual Paulista (Unesp)Saad Hossne, Rogério [UNESP]Sassaki, Ligia Yukie [UNESP]Baima, Julio Pinheiro [UNESP]de Meira JÚnior, José Donizeti [UNESP]Campos, Luana Moraes [UNESP]2019-10-06T16:09:57Z2019-10-06T16:09:57Z2018-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article252-257application/pdfhttp://dx.doi.org/10.1590/s0004-2803.201800000-63Arquivos de Gastroenterologia, v. 55, n. 3, p. 252-257, 2018.1678-42190004-2803http://hdl.handle.net/11449/18849210.1590/s0004-2803.201800000-63S0004-280320180023002522-s2.0-85058416382S0004-28032018002300252.pdf4734747821898178Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivos de Gastroenterologiainfo:eu-repo/semantics/openAccess2024-08-14T17:37:05Zoai:repositorio.unesp.br:11449/188492Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T17:37:05Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Analysis of risk factors and postoperative complications in patients with crohn’s disease
Análise dos fatores de risco e complicações pós-operatórias em pacientes portadores de doença de crohn
title Analysis of risk factors and postoperative complications in patients with crohn’s disease
spellingShingle Analysis of risk factors and postoperative complications in patients with crohn’s disease
Saad Hossne, Rogério [UNESP]
Digestive system surgical procedures
Inflammatory bowel disease
Postoperative complications
Risk factors
Secondary prevention
title_short Analysis of risk factors and postoperative complications in patients with crohn’s disease
title_full Analysis of risk factors and postoperative complications in patients with crohn’s disease
title_fullStr Analysis of risk factors and postoperative complications in patients with crohn’s disease
title_full_unstemmed Analysis of risk factors and postoperative complications in patients with crohn’s disease
title_sort Analysis of risk factors and postoperative complications in patients with crohn’s disease
author Saad Hossne, Rogério [UNESP]
author_facet Saad Hossne, Rogério [UNESP]
Sassaki, Ligia Yukie [UNESP]
Baima, Julio Pinheiro [UNESP]
de Meira JÚnior, José Donizeti [UNESP]
Campos, Luana Moraes [UNESP]
author_role author
author2 Sassaki, Ligia Yukie [UNESP]
Baima, Julio Pinheiro [UNESP]
de Meira JÚnior, José Donizeti [UNESP]
Campos, Luana Moraes [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Saad Hossne, Rogério [UNESP]
Sassaki, Ligia Yukie [UNESP]
Baima, Julio Pinheiro [UNESP]
de Meira JÚnior, José Donizeti [UNESP]
Campos, Luana Moraes [UNESP]
dc.subject.por.fl_str_mv Digestive system surgical procedures
Inflammatory bowel disease
Postoperative complications
Risk factors
Secondary prevention
topic Digestive system surgical procedures
Inflammatory bowel disease
Postoperative complications
Risk factors
Secondary prevention
description Background – The post-operative complications rate is greater in patients with Crohn’s disease than in other abdominal surgeries due to other benign conditions. Prevention and management of such complications are important factors in the care of these patients. Objective – The objectives of this research are to analyze the rate of postoperative complications and the major risk factors in patients with Crohn’s disease. Methods – A descriptive and retrospective study based on analysis of medical records of patients with Crohn’s disease undergoing ileal and/or colonic resection, which analyzed the main surgical complications and their major risk factors. Results – Forty-four surgical procedures and thirty-seven patients were analyzed. Most were female (56.7%). Postoperative complications were observed in 18 (40.9%) surgeries. The disease duration (P=0.04), the penetrating behavior (P=0.013), the time between diagnosis and the first surgery (P=0.04), malnutrition with low body mass index (BMI), duration of surgery (P=0.016), and the size of the removed specimen (P=0.014) were associated with higher rates of complications. The use of drugs blocking tumor necrosis factor up to eight weeks before surgery was not significantly associated with higher complications rates or increased need for reoperation. Conclusion – The complication rate observed in this study is similar to published data. The duration of the disease, the penetrating behavior, the size of the removed specimen, the duration of the surgery, and BMI are important risk factors for perioperative complications in Crohn’s disease.
publishDate 2018
dc.date.none.fl_str_mv 2018-07-01
2019-10-06T16:09:57Z
2019-10-06T16:09:57Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/s0004-2803.201800000-63
Arquivos de Gastroenterologia, v. 55, n. 3, p. 252-257, 2018.
1678-4219
0004-2803
http://hdl.handle.net/11449/188492
10.1590/s0004-2803.201800000-63
S0004-28032018002300252
2-s2.0-85058416382
S0004-28032018002300252.pdf
4734747821898178
url http://dx.doi.org/10.1590/s0004-2803.201800000-63
http://hdl.handle.net/11449/188492
identifier_str_mv Arquivos de Gastroenterologia, v. 55, n. 3, p. 252-257, 2018.
1678-4219
0004-2803
10.1590/s0004-2803.201800000-63
S0004-28032018002300252
2-s2.0-85058416382
S0004-28032018002300252.pdf
4734747821898178
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos de Gastroenterologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 252-257
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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