Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1678-91992006000400005 http://hdl.handle.net/11449/69206 |
Resumo: | The presence of Staphylococcus aureus in the nasal cavities and pericatheter skin of peritoneal dialysis patients put them at high risk of developing peritonitis. However, it is not clear whether the presence of coagulase-negative staphylococci (CNS) in the nasal passages and skin of patients is related to subsequent occurrence of peritoneal infection. The aim of the present study was to verify the relationship between endogenous sources of S. aureus and CNS and occurrence of peritonitis in patients undergoing peritoneal dialysis. Thirty-two patients on peritoneal hemodialysis were observed for 18 months. Staphylococcus species present in their nasal passage, pericatheter skin and peritoneal effluent were identified and compared based on drug susceptibility tests and dendrograms, which were drawn to better visualize the similarity among strains from extraperitoneal sites as well as their involvement in the causes of infection. Out of 288 Staphylococcus strains isolated, 155 (53.8%) were detected in the nasal cavity, 122 (42.4%) on the skin, and 11 (3.8%) in the peritoneal effluent of patients who developed peritonitis during the study. The most frequent Staphylococcus species were CNS (78.1%), compared with S. aureus (21.9%). Among CNS, S. epidermidis was predominant (64.4%), followed by S. warneri (15.1%), S. haemolyticus (10.7%), and other species (9.8%). Seven (64%) out of 11 cases of peritonitis analyzed presented similar strains. The same strain was isolated from different sites in two (66%) out of three S. aureus infection cases. In the six cases of S. epidermidis peritonitis, the species that caused infection was also found in the normal flora. From these, two cases (33%) presented highly similar strains and in three cases (50%), it was difficult to group strains as to similarity. Patients colonized with multidrug-resistant S. epidermidis strains were more predisposed to infection. Results demonstrated that an endogenous source of S. epidermidis could cause peritonitis in peritoneal dialysis patients, similarly to what has been observed with S. aureus. |
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Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococciCarriersCoagulase-negative staphylococciPeritoneal dialysisPeritonitisStaphylococcus aureusStaphylococcusStaphylococcus epidermidisStaphylococcus haemolyticusStaphylococcus warneriThe presence of Staphylococcus aureus in the nasal cavities and pericatheter skin of peritoneal dialysis patients put them at high risk of developing peritonitis. However, it is not clear whether the presence of coagulase-negative staphylococci (CNS) in the nasal passages and skin of patients is related to subsequent occurrence of peritoneal infection. The aim of the present study was to verify the relationship between endogenous sources of S. aureus and CNS and occurrence of peritonitis in patients undergoing peritoneal dialysis. Thirty-two patients on peritoneal hemodialysis were observed for 18 months. Staphylococcus species present in their nasal passage, pericatheter skin and peritoneal effluent were identified and compared based on drug susceptibility tests and dendrograms, which were drawn to better visualize the similarity among strains from extraperitoneal sites as well as their involvement in the causes of infection. Out of 288 Staphylococcus strains isolated, 155 (53.8%) were detected in the nasal cavity, 122 (42.4%) on the skin, and 11 (3.8%) in the peritoneal effluent of patients who developed peritonitis during the study. The most frequent Staphylococcus species were CNS (78.1%), compared with S. aureus (21.9%). Among CNS, S. epidermidis was predominant (64.4%), followed by S. warneri (15.1%), S. haemolyticus (10.7%), and other species (9.8%). Seven (64%) out of 11 cases of peritonitis analyzed presented similar strains. The same strain was isolated from different sites in two (66%) out of three S. aureus infection cases. In the six cases of S. epidermidis peritonitis, the species that caused infection was also found in the normal flora. From these, two cases (33%) presented highly similar strains and in three cases (50%), it was difficult to group strains as to similarity. Patients colonized with multidrug-resistant S. epidermidis strains were more predisposed to infection. Results demonstrated that an endogenous source of S. epidermidis could cause peritonitis in peritoneal dialysis patients, similarly to what has been observed with S. aureus.Department of Clinical Medicine Botucatu School of Medicine São Paulo, University, Botucatu, São Paulo StateDepartment of Microbiology and Immunology Institute of Biosciences UNESP, Botucatu, São Paulo StateDepartment of Biostatistics Institute of Biosciences UNESP, Botucatu, São PauloDepartamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Caixa Postal 510, 18618-000, Botucatu, SPDepartment of Microbiology and Immunology Institute of Biosciences UNESP, Botucatu, São Paulo StateDepartment of Biostatistics Institute of Biosciences UNESP, Botucatu, São PauloDepartamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Caixa Postal 510, 18618-000, Botucatu, SPUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Batalha, J. E N [UNESP]Caramori, J. C TCorrente, J. E. [UNESP]Montelli, A. C.Barretti, Pasqual [UNESP]Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP]2014-05-27T11:22:01Z2014-05-27T11:22:01Z2006-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article578-594application/pdfhttp://dx.doi.org/10.1590/S1678-91992006000400005Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 4, p. 578-594, 2006.1678-9199http://hdl.handle.net/11449/6920610.1590/S1678-91992006000400005S1678-91992006000400005WOS:0002462821000052-s2.0-338462838092-s2.0-33846283809.pdf549641198389347901156477723159730000-0001-5478-49960000-0003-4979-4836Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2023-10-31T06:13:53Zoai:repositorio.unesp.br:11449/69206Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:34:03.536407Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci |
title |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci |
spellingShingle |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci Batalha, J. E N [UNESP] Carriers Coagulase-negative staphylococci Peritoneal dialysis Peritonitis Staphylococcus aureus Staphylococcus Staphylococcus epidermidis Staphylococcus haemolyticus Staphylococcus warneri |
title_short |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci |
title_full |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci |
title_fullStr |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci |
title_full_unstemmed |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci |
title_sort |
Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci |
author |
Batalha, J. E N [UNESP] |
author_facet |
Batalha, J. E N [UNESP] Caramori, J. C T Corrente, J. E. [UNESP] Montelli, A. C. Barretti, Pasqual [UNESP] Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP] |
author_role |
author |
author2 |
Caramori, J. C T Corrente, J. E. [UNESP] Montelli, A. C. Barretti, Pasqual [UNESP] Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Batalha, J. E N [UNESP] Caramori, J. C T Corrente, J. E. [UNESP] Montelli, A. C. Barretti, Pasqual [UNESP] Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP] |
dc.subject.por.fl_str_mv |
Carriers Coagulase-negative staphylococci Peritoneal dialysis Peritonitis Staphylococcus aureus Staphylococcus Staphylococcus epidermidis Staphylococcus haemolyticus Staphylococcus warneri |
topic |
Carriers Coagulase-negative staphylococci Peritoneal dialysis Peritonitis Staphylococcus aureus Staphylococcus Staphylococcus epidermidis Staphylococcus haemolyticus Staphylococcus warneri |
description |
The presence of Staphylococcus aureus in the nasal cavities and pericatheter skin of peritoneal dialysis patients put them at high risk of developing peritonitis. However, it is not clear whether the presence of coagulase-negative staphylococci (CNS) in the nasal passages and skin of patients is related to subsequent occurrence of peritoneal infection. The aim of the present study was to verify the relationship between endogenous sources of S. aureus and CNS and occurrence of peritonitis in patients undergoing peritoneal dialysis. Thirty-two patients on peritoneal hemodialysis were observed for 18 months. Staphylococcus species present in their nasal passage, pericatheter skin and peritoneal effluent were identified and compared based on drug susceptibility tests and dendrograms, which were drawn to better visualize the similarity among strains from extraperitoneal sites as well as their involvement in the causes of infection. Out of 288 Staphylococcus strains isolated, 155 (53.8%) were detected in the nasal cavity, 122 (42.4%) on the skin, and 11 (3.8%) in the peritoneal effluent of patients who developed peritonitis during the study. The most frequent Staphylococcus species were CNS (78.1%), compared with S. aureus (21.9%). Among CNS, S. epidermidis was predominant (64.4%), followed by S. warneri (15.1%), S. haemolyticus (10.7%), and other species (9.8%). Seven (64%) out of 11 cases of peritonitis analyzed presented similar strains. The same strain was isolated from different sites in two (66%) out of three S. aureus infection cases. In the six cases of S. epidermidis peritonitis, the species that caused infection was also found in the normal flora. From these, two cases (33%) presented highly similar strains and in three cases (50%), it was difficult to group strains as to similarity. Patients colonized with multidrug-resistant S. epidermidis strains were more predisposed to infection. Results demonstrated that an endogenous source of S. epidermidis could cause peritonitis in peritoneal dialysis patients, similarly to what has been observed with S. aureus. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-11-01 2014-05-27T11:22:01Z 2014-05-27T11:22:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1678-91992006000400005 Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 4, p. 578-594, 2006. 1678-9199 http://hdl.handle.net/11449/69206 10.1590/S1678-91992006000400005 S1678-91992006000400005 WOS:000246282100005 2-s2.0-33846283809 2-s2.0-33846283809.pdf 5496411983893479 0115647772315973 0000-0001-5478-4996 0000-0003-4979-4836 |
url |
http://dx.doi.org/10.1590/S1678-91992006000400005 http://hdl.handle.net/11449/69206 |
identifier_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 4, p. 578-594, 2006. 1678-9199 10.1590/S1678-91992006000400005 S1678-91992006000400005 WOS:000246282100005 2-s2.0-33846283809 2-s2.0-33846283809.pdf 5496411983893479 0115647772315973 0000-0001-5478-4996 0000-0003-4979-4836 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases 1.782 0,573 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
578-594 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128671993561088 |