Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci

Detalhes bibliográficos
Autor(a) principal: Batalha, J. E N [UNESP]
Data de Publicação: 2006
Outros Autores: Caramori, J. C T, Corrente, J. E. [UNESP], Montelli, A. C., Barretti, Pasqual [UNESP], Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-91992006000400005
http://hdl.handle.net/11449/69206
Resumo: The presence of Staphylococcus aureus in the nasal cavities and pericatheter skin of peritoneal dialysis patients put them at high risk of developing peritonitis. However, it is not clear whether the presence of coagulase-negative staphylococci (CNS) in the nasal passages and skin of patients is related to subsequent occurrence of peritoneal infection. The aim of the present study was to verify the relationship between endogenous sources of S. aureus and CNS and occurrence of peritonitis in patients undergoing peritoneal dialysis. Thirty-two patients on peritoneal hemodialysis were observed for 18 months. Staphylococcus species present in their nasal passage, pericatheter skin and peritoneal effluent were identified and compared based on drug susceptibility tests and dendrograms, which were drawn to better visualize the similarity among strains from extraperitoneal sites as well as their involvement in the causes of infection. Out of 288 Staphylococcus strains isolated, 155 (53.8%) were detected in the nasal cavity, 122 (42.4%) on the skin, and 11 (3.8%) in the peritoneal effluent of patients who developed peritonitis during the study. The most frequent Staphylococcus species were CNS (78.1%), compared with S. aureus (21.9%). Among CNS, S. epidermidis was predominant (64.4%), followed by S. warneri (15.1%), S. haemolyticus (10.7%), and other species (9.8%). Seven (64%) out of 11 cases of peritonitis analyzed presented similar strains. The same strain was isolated from different sites in two (66%) out of three S. aureus infection cases. In the six cases of S. epidermidis peritonitis, the species that caused infection was also found in the normal flora. From these, two cases (33%) presented highly similar strains and in three cases (50%), it was difficult to group strains as to similarity. Patients colonized with multidrug-resistant S. epidermidis strains were more predisposed to infection. Results demonstrated that an endogenous source of S. epidermidis could cause peritonitis in peritoneal dialysis patients, similarly to what has been observed with S. aureus.
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spelling Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococciCarriersCoagulase-negative staphylococciPeritoneal dialysisPeritonitisStaphylococcus aureusStaphylococcusStaphylococcus epidermidisStaphylococcus haemolyticusStaphylococcus warneriThe presence of Staphylococcus aureus in the nasal cavities and pericatheter skin of peritoneal dialysis patients put them at high risk of developing peritonitis. However, it is not clear whether the presence of coagulase-negative staphylococci (CNS) in the nasal passages and skin of patients is related to subsequent occurrence of peritoneal infection. The aim of the present study was to verify the relationship between endogenous sources of S. aureus and CNS and occurrence of peritonitis in patients undergoing peritoneal dialysis. Thirty-two patients on peritoneal hemodialysis were observed for 18 months. Staphylococcus species present in their nasal passage, pericatheter skin and peritoneal effluent were identified and compared based on drug susceptibility tests and dendrograms, which were drawn to better visualize the similarity among strains from extraperitoneal sites as well as their involvement in the causes of infection. Out of 288 Staphylococcus strains isolated, 155 (53.8%) were detected in the nasal cavity, 122 (42.4%) on the skin, and 11 (3.8%) in the peritoneal effluent of patients who developed peritonitis during the study. The most frequent Staphylococcus species were CNS (78.1%), compared with S. aureus (21.9%). Among CNS, S. epidermidis was predominant (64.4%), followed by S. warneri (15.1%), S. haemolyticus (10.7%), and other species (9.8%). Seven (64%) out of 11 cases of peritonitis analyzed presented similar strains. The same strain was isolated from different sites in two (66%) out of three S. aureus infection cases. In the six cases of S. epidermidis peritonitis, the species that caused infection was also found in the normal flora. From these, two cases (33%) presented highly similar strains and in three cases (50%), it was difficult to group strains as to similarity. Patients colonized with multidrug-resistant S. epidermidis strains were more predisposed to infection. Results demonstrated that an endogenous source of S. epidermidis could cause peritonitis in peritoneal dialysis patients, similarly to what has been observed with S. aureus.Department of Clinical Medicine Botucatu School of Medicine São Paulo, University, Botucatu, São Paulo StateDepartment of Microbiology and Immunology Institute of Biosciences UNESP, Botucatu, São Paulo StateDepartment of Biostatistics Institute of Biosciences UNESP, Botucatu, São PauloDepartamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Caixa Postal 510, 18618-000, Botucatu, SPDepartment of Microbiology and Immunology Institute of Biosciences UNESP, Botucatu, São Paulo StateDepartment of Biostatistics Institute of Biosciences UNESP, Botucatu, São PauloDepartamento de Microbiologia e Imunologia Instituto de Biociências UNESP, Caixa Postal 510, 18618-000, Botucatu, SPUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Batalha, J. E N [UNESP]Caramori, J. C TCorrente, J. E. [UNESP]Montelli, A. C.Barretti, Pasqual [UNESP]Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP]2014-05-27T11:22:01Z2014-05-27T11:22:01Z2006-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article578-594application/pdfhttp://dx.doi.org/10.1590/S1678-91992006000400005Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 4, p. 578-594, 2006.1678-9199http://hdl.handle.net/11449/6920610.1590/S1678-91992006000400005S1678-91992006000400005WOS:0002462821000052-s2.0-338462838092-s2.0-33846283809.pdf549641198389347901156477723159730000-0001-5478-49960000-0003-4979-4836Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2023-10-31T06:13:53Zoai:repositorio.unesp.br:11449/69206Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:34:03.536407Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
title Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
spellingShingle Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
Batalha, J. E N [UNESP]
Carriers
Coagulase-negative staphylococci
Peritoneal dialysis
Peritonitis
Staphylococcus aureus
Staphylococcus
Staphylococcus epidermidis
Staphylococcus haemolyticus
Staphylococcus warneri
title_short Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
title_full Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
title_fullStr Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
title_full_unstemmed Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
title_sort Risk of peritonitis during peritoneal dialysis in carriers of Staphylococcus aureus and coagulase-negative staphylococci
author Batalha, J. E N [UNESP]
author_facet Batalha, J. E N [UNESP]
Caramori, J. C T
Corrente, J. E. [UNESP]
Montelli, A. C.
Barretti, Pasqual [UNESP]
Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP]
author_role author
author2 Caramori, J. C T
Corrente, J. E. [UNESP]
Montelli, A. C.
Barretti, Pasqual [UNESP]
Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Batalha, J. E N [UNESP]
Caramori, J. C T
Corrente, J. E. [UNESP]
Montelli, A. C.
Barretti, Pasqual [UNESP]
Cunha, Maria de Lourdes Ribeiro de Souza da [UNESP]
dc.subject.por.fl_str_mv Carriers
Coagulase-negative staphylococci
Peritoneal dialysis
Peritonitis
Staphylococcus aureus
Staphylococcus
Staphylococcus epidermidis
Staphylococcus haemolyticus
Staphylococcus warneri
topic Carriers
Coagulase-negative staphylococci
Peritoneal dialysis
Peritonitis
Staphylococcus aureus
Staphylococcus
Staphylococcus epidermidis
Staphylococcus haemolyticus
Staphylococcus warneri
description The presence of Staphylococcus aureus in the nasal cavities and pericatheter skin of peritoneal dialysis patients put them at high risk of developing peritonitis. However, it is not clear whether the presence of coagulase-negative staphylococci (CNS) in the nasal passages and skin of patients is related to subsequent occurrence of peritoneal infection. The aim of the present study was to verify the relationship between endogenous sources of S. aureus and CNS and occurrence of peritonitis in patients undergoing peritoneal dialysis. Thirty-two patients on peritoneal hemodialysis were observed for 18 months. Staphylococcus species present in their nasal passage, pericatheter skin and peritoneal effluent were identified and compared based on drug susceptibility tests and dendrograms, which were drawn to better visualize the similarity among strains from extraperitoneal sites as well as their involvement in the causes of infection. Out of 288 Staphylococcus strains isolated, 155 (53.8%) were detected in the nasal cavity, 122 (42.4%) on the skin, and 11 (3.8%) in the peritoneal effluent of patients who developed peritonitis during the study. The most frequent Staphylococcus species were CNS (78.1%), compared with S. aureus (21.9%). Among CNS, S. epidermidis was predominant (64.4%), followed by S. warneri (15.1%), S. haemolyticus (10.7%), and other species (9.8%). Seven (64%) out of 11 cases of peritonitis analyzed presented similar strains. The same strain was isolated from different sites in two (66%) out of three S. aureus infection cases. In the six cases of S. epidermidis peritonitis, the species that caused infection was also found in the normal flora. From these, two cases (33%) presented highly similar strains and in three cases (50%), it was difficult to group strains as to similarity. Patients colonized with multidrug-resistant S. epidermidis strains were more predisposed to infection. Results demonstrated that an endogenous source of S. epidermidis could cause peritonitis in peritoneal dialysis patients, similarly to what has been observed with S. aureus.
publishDate 2006
dc.date.none.fl_str_mv 2006-11-01
2014-05-27T11:22:01Z
2014-05-27T11:22:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-91992006000400005
Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 4, p. 578-594, 2006.
1678-9199
http://hdl.handle.net/11449/69206
10.1590/S1678-91992006000400005
S1678-91992006000400005
WOS:000246282100005
2-s2.0-33846283809
2-s2.0-33846283809.pdf
5496411983893479
0115647772315973
0000-0001-5478-4996
0000-0003-4979-4836
url http://dx.doi.org/10.1590/S1678-91992006000400005
http://hdl.handle.net/11449/69206
identifier_str_mv Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 4, p. 578-594, 2006.
1678-9199
10.1590/S1678-91992006000400005
S1678-91992006000400005
WOS:000246282100005
2-s2.0-33846283809
2-s2.0-33846283809.pdf
5496411983893479
0115647772315973
0000-0001-5478-4996
0000-0003-4979-4836
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Venomous Animals and Toxins Including Tropical Diseases
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dc.format.none.fl_str_mv 578-594
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
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instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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