Ação anticárie de dentifrícios com reduzida concentração de fluoreto associado à nanopartículas de trimetafosfato de sódio

• Autor(a) principal: Castilho, Flávia Campos Nantes de [UNESP]
• Data de Publicação: 2014
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/149629; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-01-30/000864493.pdf
• topic: Dentifrícios; Esmalte dentário; Fluoretos; Nanopartículas; Fosfatos; Desmineralização do dente; Dentifrices

This study evaluated the effect of low-fluoride dentifrices containing or not different concentrations of micrometric or nano-sized TMP on enamel demineralization, using a pH cycling model. Bovine enamel blocks were allocated into twelve groups (n = 12), according to the dentifrices: placebo (without F/TMP/TMPnano); 1,100 ppm F; 250 ppm F; 250 ppm F plus micrometric TMP (250-TMP), nano-sized TMP milled for 24h (250-TMPnano24) or nano-sized TMP milled for 48h (250-TMPnano48) at concentrations 0,05% 0,1% and 0,25%. Blocks were subjected to pH-cycling and treatment 2x/day with slurries of dentifrices. To evaluate mineral loss, final surface hardness (SHf) and percentage of surface hardness loss (%SH) were analyzed. Fluoride (F), calcium (Ca), phosphorus (P) and Ca/P molar ratio concentrations were determined in enamel. Data were submitted to Kruskal-Wallis test, followed by Student-Newman-Keuls' test (p < 0.05). All TMPnano concentrations reduced %SH (p ˂ 0.05). The TMPnano showed higher F, Ca, P and Ca/P content in enamel only at 0.05% (p ˂ 0.05). The 250-0.05%TMPnano48 resulted in better results considering all parameters (p ˂ 0.05). It was concluded that the anticaries effect of the 250 ppm F toothpaste containing nano-sized TMP was similar to a conventional formulation