Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1980-5373-MR-2021-0233 http://hdl.handle.net/11449/237716 |
Resumo: | Ti-34Nb-6Sn alloy were prepare by powder metallurgy milled in two different times (40 and 60 min) using Ti and Nb hydrides with or without Mg, as spacer then sintered at 700 degrees C and 800 degrees C. Characterizations were made by scanning electron microscope (SEM), X-ray diffractometer (XRD) and by Archimedes. Microhardness was measured by Vickers microhardness. Mesenchymal stein cells derived from equine bone marrow (BMMSCs) were used to evaluate the sample cytotoxicity. Hydration and dehydration process was confirmed, also the formation of brittle particles during the milling. Materials were structured under alpha and beta phase, and the samples that received Mg as a spacer had slightly lower beta phase content compared to samples without Mg, suggesting difficult alpha ->beta transformation due to the presence of barriers formed by pores. Mg provided greater porosity, and prepared milled in a shorter time promoted an increase in the macropores. Microhardness was similar to that of commercial materials (i.e., CP-Ti and also to other alloys with similar nominal composition. Cells treated with conditioned medium with the samples showed viability comparable to the control group, and after 48 h of culture on the samples, there was significant growth and more circular morphology, when adhered on materials that received Mg. |
id |
UNSP_2e4c3d3dfa66a242ecffe390c00e8d58 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/237716 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as BiomaterialBeta titanium alloyHigh energy millingBiocompatibilityBiomedical implantTi-34Nb-6Sn alloy were prepare by powder metallurgy milled in two different times (40 and 60 min) using Ti and Nb hydrides with or without Mg, as spacer then sintered at 700 degrees C and 800 degrees C. Characterizations were made by scanning electron microscope (SEM), X-ray diffractometer (XRD) and by Archimedes. Microhardness was measured by Vickers microhardness. Mesenchymal stein cells derived from equine bone marrow (BMMSCs) were used to evaluate the sample cytotoxicity. Hydration and dehydration process was confirmed, also the formation of brittle particles during the milling. Materials were structured under alpha and beta phase, and the samples that received Mg as a spacer had slightly lower beta phase content compared to samples without Mg, suggesting difficult alpha ->beta transformation due to the presence of barriers formed by pores. Mg provided greater porosity, and prepared milled in a shorter time promoted an increase in the macropores. Microhardness was similar to that of commercial materials (i.e., CP-Ti and also to other alloys with similar nominal composition. Cells treated with conditioned medium with the samples showed viability comparable to the control group, and after 48 h of culture on the samples, there was significant growth and more circular morphology, when adhered on materials that received Mg.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Univ Politecn Valencia, Univ Estadual Paulista Julio de Mesquita Filho, Dept Cirurgia Vet & Reptod Anim, Lab Med Regenerat, Botucatu, SP, BrazilUniv Politecn Valencia, Inst Tecnol Mat, Valencia, SpainUniv Sao Paulo, Inst Pesquisas Energet & Nucleases, Ctr Ciencia Mat & Tecnol, Sao Paulo, SP, BrazilUniv Estadual Paulista, Inst Biociencias Botucatu, Dept Quim & Bioquim, Botucatu, SP, BrazilUniv Politecn Valencia, Univ Estadual Paulista Julio de Mesquita Filho, Dept Cirurgia Vet & Reptod Anim, Lab Med Regenerat, Botucatu, SP, BrazilUniv Estadual Paulista, Inst Biociencias Botucatu, Dept Quim & Bioquim, Botucatu, SP, BrazilFAPESP: 2017/13876-2FAPESP: 2019/ 24237-6Univ Fed Sao Carlos, Dept Engenharia MaterialsUniversidade Estadual Paulista (UNESP)Univ Politecn ValenciaUniversidade de São Paulo (USP)Rossi, Mariana Correa [UNESP]Stievani, Fernanda de Castro [UNESP]Pfeifer, Joao Pedro Hubbe [UNESP]Martinez, Luis GallegoBorras, Vicente AmigoSaeki, Margarida Juri [UNESP]Alves, Ana Liz Garcia [UNESP]2022-11-30T13:42:46Z2022-11-30T13:42:46Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article15http://dx.doi.org/10.1590/1980-5373-MR-2021-0233Materials Research-ibero-american Journal Of Materials. Sao Carlos: Univ Fed Sao Carlos, Dept Engenharia Materials, v. 25, 15 p., 2022.1516-1439http://hdl.handle.net/11449/23771610.1590/1980-5373-MR-2021-0233WOS:000786625700001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterials Research-ibero-american Journal Of Materialsinfo:eu-repo/semantics/openAccess2022-11-30T13:42:46Zoai:repositorio.unesp.br:11449/237716Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:58:03.697527Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial |
title |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial |
spellingShingle |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial Rossi, Mariana Correa [UNESP] Beta titanium alloy High energy milling Biocompatibility Biomedical implant |
title_short |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial |
title_full |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial |
title_fullStr |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial |
title_full_unstemmed |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial |
title_sort |
Evaluation of the Physical and Biological Properties of Ti-34Nb-6Sn/Mg Alloy Obtained by Powder Metallurgy for Use as Biomaterial |
author |
Rossi, Mariana Correa [UNESP] |
author_facet |
Rossi, Mariana Correa [UNESP] Stievani, Fernanda de Castro [UNESP] Pfeifer, Joao Pedro Hubbe [UNESP] Martinez, Luis Gallego Borras, Vicente Amigo Saeki, Margarida Juri [UNESP] Alves, Ana Liz Garcia [UNESP] |
author_role |
author |
author2 |
Stievani, Fernanda de Castro [UNESP] Pfeifer, Joao Pedro Hubbe [UNESP] Martinez, Luis Gallego Borras, Vicente Amigo Saeki, Margarida Juri [UNESP] Alves, Ana Liz Garcia [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Univ Politecn Valencia Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Rossi, Mariana Correa [UNESP] Stievani, Fernanda de Castro [UNESP] Pfeifer, Joao Pedro Hubbe [UNESP] Martinez, Luis Gallego Borras, Vicente Amigo Saeki, Margarida Juri [UNESP] Alves, Ana Liz Garcia [UNESP] |
dc.subject.por.fl_str_mv |
Beta titanium alloy High energy milling Biocompatibility Biomedical implant |
topic |
Beta titanium alloy High energy milling Biocompatibility Biomedical implant |
description |
Ti-34Nb-6Sn alloy were prepare by powder metallurgy milled in two different times (40 and 60 min) using Ti and Nb hydrides with or without Mg, as spacer then sintered at 700 degrees C and 800 degrees C. Characterizations were made by scanning electron microscope (SEM), X-ray diffractometer (XRD) and by Archimedes. Microhardness was measured by Vickers microhardness. Mesenchymal stein cells derived from equine bone marrow (BMMSCs) were used to evaluate the sample cytotoxicity. Hydration and dehydration process was confirmed, also the formation of brittle particles during the milling. Materials were structured under alpha and beta phase, and the samples that received Mg as a spacer had slightly lower beta phase content compared to samples without Mg, suggesting difficult alpha ->beta transformation due to the presence of barriers formed by pores. Mg provided greater porosity, and prepared milled in a shorter time promoted an increase in the macropores. Microhardness was similar to that of commercial materials (i.e., CP-Ti and also to other alloys with similar nominal composition. Cells treated with conditioned medium with the samples showed viability comparable to the control group, and after 48 h of culture on the samples, there was significant growth and more circular morphology, when adhered on materials that received Mg. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-30T13:42:46Z 2022-11-30T13:42:46Z 2022-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1980-5373-MR-2021-0233 Materials Research-ibero-american Journal Of Materials. Sao Carlos: Univ Fed Sao Carlos, Dept Engenharia Materials, v. 25, 15 p., 2022. 1516-1439 http://hdl.handle.net/11449/237716 10.1590/1980-5373-MR-2021-0233 WOS:000786625700001 |
url |
http://dx.doi.org/10.1590/1980-5373-MR-2021-0233 http://hdl.handle.net/11449/237716 |
identifier_str_mv |
Materials Research-ibero-american Journal Of Materials. Sao Carlos: Univ Fed Sao Carlos, Dept Engenharia Materials, v. 25, 15 p., 2022. 1516-1439 10.1590/1980-5373-MR-2021-0233 WOS:000786625700001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Materials Research-ibero-american Journal Of Materials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
15 |
dc.publisher.none.fl_str_mv |
Univ Fed Sao Carlos, Dept Engenharia Materials |
publisher.none.fl_str_mv |
Univ Fed Sao Carlos, Dept Engenharia Materials |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129143684988928 |