Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Capítulo de livro |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/978-3-030-92196-5_3 http://hdl.handle.net/11449/248757 |
Resumo: | The increased worldwide prevalence of pre-diabetes and diabetes, especially type 2 diabetes, requiring different strategies for their prevention and management. A new focus is the reversal of diabetes dysbiosis, a disruption of gut microbiota homeostasis, which is closely related to elevated blood glucose levels and altered metabolic parameters. In this sense, a balanced diet plays a key role, and, particularly, probiotic and prebiotic have shown a promising role. This chapter explored current knowledge on the potential of probiotic and prebiotic to modulate glucose homeostasis. We showed that the consumption of probiotics and prebiotics is a promising strategy with a beneficial impact on gut microbiota and glycemic control. Furthermore, specific probiotic strains, such as L. acidophilus, L. casei strain Shirota, and B. lactis Bb12, have demonstrated the ability to improve parameters related to pre-diabetes and type 2 diabetes. In addition, polyphenols are emerging as a new alternative in glycemic control through the production of short chain fat acids (SCFA) and decreased lipopolysaccharides (LPS) translocation that leads to metabolic endotoxemia. Finally, the ingestion of beneficial bacteria, and foods rich in fiber and polyphenols, or a combination of them, is a good strategy for the control of pre-diabetes and type 2 diabetes, but more studies are still needed, mainly clinical trials, for these strategies are improved and widely used. |
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Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetesThe increased worldwide prevalence of pre-diabetes and diabetes, especially type 2 diabetes, requiring different strategies for their prevention and management. A new focus is the reversal of diabetes dysbiosis, a disruption of gut microbiota homeostasis, which is closely related to elevated blood glucose levels and altered metabolic parameters. In this sense, a balanced diet plays a key role, and, particularly, probiotic and prebiotic have shown a promising role. This chapter explored current knowledge on the potential of probiotic and prebiotic to modulate glucose homeostasis. We showed that the consumption of probiotics and prebiotics is a promising strategy with a beneficial impact on gut microbiota and glycemic control. Furthermore, specific probiotic strains, such as L. acidophilus, L. casei strain Shirota, and B. lactis Bb12, have demonstrated the ability to improve parameters related to pre-diabetes and type 2 diabetes. In addition, polyphenols are emerging as a new alternative in glycemic control through the production of short chain fat acids (SCFA) and decreased lipopolysaccharides (LPS) translocation that leads to metabolic endotoxemia. Finally, the ingestion of beneficial bacteria, and foods rich in fiber and polyphenols, or a combination of them, is a good strategy for the control of pre-diabetes and type 2 diabetes, but more studies are still needed, mainly clinical trials, for these strategies are improved and widely used.Department of Food and Nutrition School of Pharmaceutical Sciences São Paulo State University (UNESP)Department of Food and Nutrition School of Pharmaceutical Sciences São Paulo State University (UNESP)Universidade Estadual Paulista (UNESP)Ramos, Fernanda Maria Manzini [UNESP]Salgaço, Mateus Kawata [UNESP]Cesar, Thais [UNESP]Sivieri, Katia [UNESP]2023-07-29T13:52:54Z2023-07-29T13:52:54Z2022-03-08info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart77-100http://dx.doi.org/10.1007/978-3-030-92196-5_3Natural Products in Obesity and Diabetes: Therapeutic Potential and Role in Prevention and Treatment, p. 77-100.http://hdl.handle.net/11449/24875710.1007/978-3-030-92196-5_32-s2.0-85154578047Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengNatural Products in Obesity and Diabetes: Therapeutic Potential and Role in Prevention and Treatmentinfo:eu-repo/semantics/openAccess2024-06-21T12:47:24Zoai:repositorio.unesp.br:11449/248757Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:56:21.406691Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes |
title |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes |
spellingShingle |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes Ramos, Fernanda Maria Manzini [UNESP] |
title_short |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes |
title_full |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes |
title_fullStr |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes |
title_full_unstemmed |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes |
title_sort |
Impact of probiotic and prebiotic on gut microbiota in pre-diabetes and type 2 diabetes |
author |
Ramos, Fernanda Maria Manzini [UNESP] |
author_facet |
Ramos, Fernanda Maria Manzini [UNESP] Salgaço, Mateus Kawata [UNESP] Cesar, Thais [UNESP] Sivieri, Katia [UNESP] |
author_role |
author |
author2 |
Salgaço, Mateus Kawata [UNESP] Cesar, Thais [UNESP] Sivieri, Katia [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Ramos, Fernanda Maria Manzini [UNESP] Salgaço, Mateus Kawata [UNESP] Cesar, Thais [UNESP] Sivieri, Katia [UNESP] |
description |
The increased worldwide prevalence of pre-diabetes and diabetes, especially type 2 diabetes, requiring different strategies for their prevention and management. A new focus is the reversal of diabetes dysbiosis, a disruption of gut microbiota homeostasis, which is closely related to elevated blood glucose levels and altered metabolic parameters. In this sense, a balanced diet plays a key role, and, particularly, probiotic and prebiotic have shown a promising role. This chapter explored current knowledge on the potential of probiotic and prebiotic to modulate glucose homeostasis. We showed that the consumption of probiotics and prebiotics is a promising strategy with a beneficial impact on gut microbiota and glycemic control. Furthermore, specific probiotic strains, such as L. acidophilus, L. casei strain Shirota, and B. lactis Bb12, have demonstrated the ability to improve parameters related to pre-diabetes and type 2 diabetes. In addition, polyphenols are emerging as a new alternative in glycemic control through the production of short chain fat acids (SCFA) and decreased lipopolysaccharides (LPS) translocation that leads to metabolic endotoxemia. Finally, the ingestion of beneficial bacteria, and foods rich in fiber and polyphenols, or a combination of them, is a good strategy for the control of pre-diabetes and type 2 diabetes, but more studies are still needed, mainly clinical trials, for these strategies are improved and widely used. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-08 2023-07-29T13:52:54Z 2023-07-29T13:52:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bookPart |
format |
bookPart |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/978-3-030-92196-5_3 Natural Products in Obesity and Diabetes: Therapeutic Potential and Role in Prevention and Treatment, p. 77-100. http://hdl.handle.net/11449/248757 10.1007/978-3-030-92196-5_3 2-s2.0-85154578047 |
url |
http://dx.doi.org/10.1007/978-3-030-92196-5_3 http://hdl.handle.net/11449/248757 |
identifier_str_mv |
Natural Products in Obesity and Diabetes: Therapeutic Potential and Role in Prevention and Treatment, p. 77-100. 10.1007/978-3-030-92196-5_3 2-s2.0-85154578047 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Natural Products in Obesity and Diabetes: Therapeutic Potential and Role in Prevention and Treatment |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
77-100 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129000987426816 |