Pênfigo Foliáceo em cães

Detalhes bibliográficos
Autor(a) principal: Zanholo, Amanda Borges [UNESP]
Data de Publicação: 2011
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/121810
Resumo: Pemphigus complex in animals is considered rare, but not so when compared with the occurrence of other autoimmune diseases. Pemphigus Foliaceus in dogs is the most common varieties of pemphigus and is characterized clinically by intraepidermal pustules, starting on the face and ears, pads, groin, and may become multifocal or generalized in six months. As the pustules are very fragile, the lesions usually found are secondary, which may range from dry to collarettes epidermal crusting, and nasal depigmentation. The diagnosis is difficult because presents sintomatology similar to other diseases and laboratory diagnosis more precise through the histopathological examination of pustules integrate (biopsy), which are rarely found. The treatment, although of the individual treatment regimen, is based on treating opportunistic diseases and immunosuppressing the animal in order to decrease the production of autoantibodies. The drugs of choice depend on the clinical presentation, however is usually oral prednisone and azathioprine in the dog and combined immunosuppressive therapy. Should make use daily until the disease is inactive and gradually decrease the dose until have the minimum effective dose, preferably on alternate days for the remission of the disease. Prognosis of pemphigus varies according to disease stage and treatment established. Pemphigus foliaceus is less serious nonetheless might be fatal without treatment
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spelling Pênfigo Foliáceo em cãesCão - DoençasPenfigoPemphigusFoliaceusDogsPemphigus complex in animals is considered rare, but not so when compared with the occurrence of other autoimmune diseases. Pemphigus Foliaceus in dogs is the most common varieties of pemphigus and is characterized clinically by intraepidermal pustules, starting on the face and ears, pads, groin, and may become multifocal or generalized in six months. As the pustules are very fragile, the lesions usually found are secondary, which may range from dry to collarettes epidermal crusting, and nasal depigmentation. The diagnosis is difficult because presents sintomatology similar to other diseases and laboratory diagnosis more precise through the histopathological examination of pustules integrate (biopsy), which are rarely found. The treatment, although of the individual treatment regimen, is based on treating opportunistic diseases and immunosuppressing the animal in order to decrease the production of autoantibodies. The drugs of choice depend on the clinical presentation, however is usually oral prednisone and azathioprine in the dog and combined immunosuppressive therapy. Should make use daily until the disease is inactive and gradually decrease the dose until have the minimum effective dose, preferably on alternate days for the remission of the disease. Prognosis of pemphigus varies according to disease stage and treatment established. Pemphigus foliaceus is less serious nonetheless might be fatal without treatmentO complexo Pênfigo em animais é considerado raro, mas não tanto ao se comparar com a ocorrência de outras doença autoimunes. O Pênfigo Foliáceo em cães é a forma mais comum das variedades de pênfigo e se caracteriza clinicamente por pústulas intra-epidérmicas, começando na face e orelhas, coxins, virilha e podendo se tornar multifocal ou generalizada em seis meses. Como as pústulas são muito frágeis, as lesões geralmente encontradas são as secundárias, que podem variar de crostas secas a colaretes epidérmicos, além de despigmentação nasal. O diagnóstico é difícil por apresentar sintomatologia semelhante com outras doenças e por seu diagnóstico laboratorial ser mais preciso com o exame histopatológico de pústulas integras (biópsia), sendo estas raramente encontradas. O tratamento, apesar de ter esquema terapêutico individual, se baseia em tratar as doenças oportunistas e imunossuprimir o animal com a finalidade de diminuir a produção de auto-anticorpos. Os medicamentos de escolha dependem da apresentação clínica, mas geralmente é a Prednisona oral e no cão e a Azatioprina na terapia imunossupressora combinada. Deve-se fazer o uso diariamente até que a doença esteja inativa e diminuir gradativamente a dose até se ter a dose mínima efetiva, de preferência em dias alternados para remissão da doença. O prognóstico do pênfigo é variável de acordo com o estágio da doença e do tratamento estabelecido. O pênfigo foliáceo é menos grave, mas sem tratamento pode ser fatalUniversidade Estadual Paulista (Unesp)Paes, Antonio Carlos [UNESP]Universidade Estadual Paulista (Unesp)Zanholo, Amanda Borges [UNESP]2015-03-23T15:29:49Z2015-03-23T15:29:49Z2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisapplication/pdfZANHOLO, Amanda Borges. Pênfigo Foliáceo em cães. 2011. 1 CD-ROM. Trabalho de conclusão de curso (licenciatura - Medicina Veterinária) - Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, 2011.http://hdl.handle.net/11449/121810000685755zanholo_ab_tcc_botfmvz.pdf3221552979448328Alephreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporinfo:eu-repo/semantics/openAccess2024-09-09T14:34:52Zoai:repositorio.unesp.br:11449/121810Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T14:34:52Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Pênfigo Foliáceo em cães
title Pênfigo Foliáceo em cães
spellingShingle Pênfigo Foliáceo em cães
Zanholo, Amanda Borges [UNESP]
Cão - Doenças
Penfigo
Pemphigus
Foliaceus
Dogs
title_short Pênfigo Foliáceo em cães
title_full Pênfigo Foliáceo em cães
title_fullStr Pênfigo Foliáceo em cães
title_full_unstemmed Pênfigo Foliáceo em cães
title_sort Pênfigo Foliáceo em cães
author Zanholo, Amanda Borges [UNESP]
author_facet Zanholo, Amanda Borges [UNESP]
author_role author
dc.contributor.none.fl_str_mv Paes, Antonio Carlos [UNESP]
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Zanholo, Amanda Borges [UNESP]
dc.subject.por.fl_str_mv Cão - Doenças
Penfigo
Pemphigus
Foliaceus
Dogs
topic Cão - Doenças
Penfigo
Pemphigus
Foliaceus
Dogs
description Pemphigus complex in animals is considered rare, but not so when compared with the occurrence of other autoimmune diseases. Pemphigus Foliaceus in dogs is the most common varieties of pemphigus and is characterized clinically by intraepidermal pustules, starting on the face and ears, pads, groin, and may become multifocal or generalized in six months. As the pustules are very fragile, the lesions usually found are secondary, which may range from dry to collarettes epidermal crusting, and nasal depigmentation. The diagnosis is difficult because presents sintomatology similar to other diseases and laboratory diagnosis more precise through the histopathological examination of pustules integrate (biopsy), which are rarely found. The treatment, although of the individual treatment regimen, is based on treating opportunistic diseases and immunosuppressing the animal in order to decrease the production of autoantibodies. The drugs of choice depend on the clinical presentation, however is usually oral prednisone and azathioprine in the dog and combined immunosuppressive therapy. Should make use daily until the disease is inactive and gradually decrease the dose until have the minimum effective dose, preferably on alternate days for the remission of the disease. Prognosis of pemphigus varies according to disease stage and treatment established. Pemphigus foliaceus is less serious nonetheless might be fatal without treatment
publishDate 2011
dc.date.none.fl_str_mv 2011
2015-03-23T15:29:49Z
2015-03-23T15:29:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bachelorThesis
format bachelorThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv ZANHOLO, Amanda Borges. Pênfigo Foliáceo em cães. 2011. 1 CD-ROM. Trabalho de conclusão de curso (licenciatura - Medicina Veterinária) - Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, 2011.
http://hdl.handle.net/11449/121810
000685755
zanholo_ab_tcc_botfmvz.pdf
3221552979448328
identifier_str_mv ZANHOLO, Amanda Borges. Pênfigo Foliáceo em cães. 2011. 1 CD-ROM. Trabalho de conclusão de curso (licenciatura - Medicina Veterinária) - Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, 2011.
000685755
zanholo_ab_tcc_botfmvz.pdf
3221552979448328
url http://hdl.handle.net/11449/121810
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp)
publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.source.none.fl_str_mv Aleph
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1813546568038481920