Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial

Detalhes bibliográficos
Autor(a) principal: Curado Lopes, Lorena Cristina
Data de Publicação: 2019
Outros Autores: Mota, Joao Felipe, Prestes, Jonato, Schincaglia, Raquel Machado, Silva, Debora Mendes, Queiroz, Nayara Pedatella, Vaz de Souza Freitas, Ana Tereza, Lira, Fabio Santos [UNESP], Gondim Peixoto, Maria do Rosario
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.apmr.2019.06.006
http://hdl.handle.net/11449/196320
Resumo: Objective: To compare the effects of high vs moderate loads of intradialytic resistance training (RT) on body composition, sarcopenia prevalence, functional capacity, inflammatory markers, and quality of life (QoL) in individuals on hemodialysis. Design: A pilot randomized clinical trial. Setting: Two hemodialysis centers. Participants: Individuals on hemodialysis (N=80; 51% men, aged 30-75y) in treatment for at least 3 months, adequately dialyzed (Kt/V >= 1.2, where K is dialyzer clearance in mL/min, t is time, and V is volume of water) with vascular access via arteriovenous fistula. Interventions: The 12 weeks of intradialytic RT was performed 3 times per week. The training groups were: high-load intradialytic group (HLG, 8-10 repetitions), moderate-load intradialytic group (MLG, 16-18 repetitions), and control group (CG, stretching exercise). The total training volume was equalized among training groups. Main Outcome Measures: Lean leg mass was assessed by a dual-energy x-ray absorptiometry; functional capacity was assessed by Short Physical Performance Battery and Timed Up and Go test; and QoL was assessed by Kidney Disease QoL Instrument, inflammatory markers, and sarcopenia. Results: After the training period, the HLG increased lean leg mass compared with the CG. The HLG also displayed improvements in the pain and physical function domains. The skeletal muscle index and functional capacity increased in both RT protocols. The prevalence of sarcopenia was reduced 14.3% and 25% in the MLG and HLG, respectively, while there was an increase of 10% in the CG. No differences were observed in cytokines after intervention. Conclusions: High-load intradialytic RT was associated with gains in lean leg mass and QoL while functional capacity, appendicular muscle mass, and sarcopenia status were improved regardless of the RT load. (C) 2019 by the American Congress of Rehabilitation Medicine
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spelling Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot TrialQuality of lifeRehabilitationRenal dialysisResistance trainingSarcopeniaObjective: To compare the effects of high vs moderate loads of intradialytic resistance training (RT) on body composition, sarcopenia prevalence, functional capacity, inflammatory markers, and quality of life (QoL) in individuals on hemodialysis. Design: A pilot randomized clinical trial. Setting: Two hemodialysis centers. Participants: Individuals on hemodialysis (N=80; 51% men, aged 30-75y) in treatment for at least 3 months, adequately dialyzed (Kt/V >= 1.2, where K is dialyzer clearance in mL/min, t is time, and V is volume of water) with vascular access via arteriovenous fistula. Interventions: The 12 weeks of intradialytic RT was performed 3 times per week. The training groups were: high-load intradialytic group (HLG, 8-10 repetitions), moderate-load intradialytic group (MLG, 16-18 repetitions), and control group (CG, stretching exercise). The total training volume was equalized among training groups. Main Outcome Measures: Lean leg mass was assessed by a dual-energy x-ray absorptiometry; functional capacity was assessed by Short Physical Performance Battery and Timed Up and Go test; and QoL was assessed by Kidney Disease QoL Instrument, inflammatory markers, and sarcopenia. Results: After the training period, the HLG increased lean leg mass compared with the CG. The HLG also displayed improvements in the pain and physical function domains. The skeletal muscle index and functional capacity increased in both RT protocols. The prevalence of sarcopenia was reduced 14.3% and 25% in the MLG and HLG, respectively, while there was an increase of 10% in the CG. No differences were observed in cytokines after intervention. Conclusions: High-load intradialytic RT was associated with gains in lean leg mass and QoL while functional capacity, appendicular muscle mass, and sarcopenia status were improved regardless of the RT load. (C) 2019 by the American Congress of Rehabilitation MedicineCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Univ Fed Goias, Fac Nutr, Clin Nutr & Sports Res Lab, St 227,Block 68, Goiania, Go, BrazilUniv Catolica Brasilia, Postgrad Program Phys Educ, Brasilia, DF, BrazilSao Paulo State Univ IUNESP, Exercise & Immunometab Res Grp, Postgrad Program Movement Sci, Dept Phys Educ, Presidente Prudente, SP, BrazilSao Paulo State Univ IUNESP, Exercise & Immunometab Res Grp, Postgrad Program Movement Sci, Dept Phys Educ, Presidente Prudente, SP, BrazilElsevier B.V.Universidade Federal de Goiás (UFG)Univ Catolica BrasiliaUniversidade Estadual Paulista (Unesp)Curado Lopes, Lorena CristinaMota, Joao FelipePrestes, JonatoSchincaglia, Raquel MachadoSilva, Debora MendesQueiroz, Nayara PedatellaVaz de Souza Freitas, Ana TerezaLira, Fabio Santos [UNESP]Gondim Peixoto, Maria do Rosario2020-12-10T19:40:49Z2020-12-10T19:40:49Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2151-2158http://dx.doi.org/10.1016/j.apmr.2019.06.006Archives Of Physical Medicine And Rehabilitation. Philadelphia: W B Saunders Co-elsevier Inc, v. 100, n. 11, p. 2151-2158, 2019.0003-9993http://hdl.handle.net/11449/19632010.1016/j.apmr.2019.06.006WOS:000496035600020Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArchives Of Physical Medicine And Rehabilitationinfo:eu-repo/semantics/openAccess2021-10-23T07:07:20Zoai:repositorio.unesp.br:11449/196320Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T07:07:20Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
title Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
spellingShingle Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
Curado Lopes, Lorena Cristina
Quality of life
Rehabilitation
Renal dialysis
Resistance training
Sarcopenia
title_short Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
title_full Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
title_fullStr Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
title_full_unstemmed Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
title_sort Intradialytic Resistance Training Improves Functional Capacity and Lean Mass Gain in Individuals on Hemodialysis: A Randomized Pilot Trial
author Curado Lopes, Lorena Cristina
author_facet Curado Lopes, Lorena Cristina
Mota, Joao Felipe
Prestes, Jonato
Schincaglia, Raquel Machado
Silva, Debora Mendes
Queiroz, Nayara Pedatella
Vaz de Souza Freitas, Ana Tereza
Lira, Fabio Santos [UNESP]
Gondim Peixoto, Maria do Rosario
author_role author
author2 Mota, Joao Felipe
Prestes, Jonato
Schincaglia, Raquel Machado
Silva, Debora Mendes
Queiroz, Nayara Pedatella
Vaz de Souza Freitas, Ana Tereza
Lira, Fabio Santos [UNESP]
Gondim Peixoto, Maria do Rosario
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de Goiás (UFG)
Univ Catolica Brasilia
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Curado Lopes, Lorena Cristina
Mota, Joao Felipe
Prestes, Jonato
Schincaglia, Raquel Machado
Silva, Debora Mendes
Queiroz, Nayara Pedatella
Vaz de Souza Freitas, Ana Tereza
Lira, Fabio Santos [UNESP]
Gondim Peixoto, Maria do Rosario
dc.subject.por.fl_str_mv Quality of life
Rehabilitation
Renal dialysis
Resistance training
Sarcopenia
topic Quality of life
Rehabilitation
Renal dialysis
Resistance training
Sarcopenia
description Objective: To compare the effects of high vs moderate loads of intradialytic resistance training (RT) on body composition, sarcopenia prevalence, functional capacity, inflammatory markers, and quality of life (QoL) in individuals on hemodialysis. Design: A pilot randomized clinical trial. Setting: Two hemodialysis centers. Participants: Individuals on hemodialysis (N=80; 51% men, aged 30-75y) in treatment for at least 3 months, adequately dialyzed (Kt/V >= 1.2, where K is dialyzer clearance in mL/min, t is time, and V is volume of water) with vascular access via arteriovenous fistula. Interventions: The 12 weeks of intradialytic RT was performed 3 times per week. The training groups were: high-load intradialytic group (HLG, 8-10 repetitions), moderate-load intradialytic group (MLG, 16-18 repetitions), and control group (CG, stretching exercise). The total training volume was equalized among training groups. Main Outcome Measures: Lean leg mass was assessed by a dual-energy x-ray absorptiometry; functional capacity was assessed by Short Physical Performance Battery and Timed Up and Go test; and QoL was assessed by Kidney Disease QoL Instrument, inflammatory markers, and sarcopenia. Results: After the training period, the HLG increased lean leg mass compared with the CG. The HLG also displayed improvements in the pain and physical function domains. The skeletal muscle index and functional capacity increased in both RT protocols. The prevalence of sarcopenia was reduced 14.3% and 25% in the MLG and HLG, respectively, while there was an increase of 10% in the CG. No differences were observed in cytokines after intervention. Conclusions: High-load intradialytic RT was associated with gains in lean leg mass and QoL while functional capacity, appendicular muscle mass, and sarcopenia status were improved regardless of the RT load. (C) 2019 by the American Congress of Rehabilitation Medicine
publishDate 2019
dc.date.none.fl_str_mv 2019-11-01
2020-12-10T19:40:49Z
2020-12-10T19:40:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.apmr.2019.06.006
Archives Of Physical Medicine And Rehabilitation. Philadelphia: W B Saunders Co-elsevier Inc, v. 100, n. 11, p. 2151-2158, 2019.
0003-9993
http://hdl.handle.net/11449/196320
10.1016/j.apmr.2019.06.006
WOS:000496035600020
url http://dx.doi.org/10.1016/j.apmr.2019.06.006
http://hdl.handle.net/11449/196320
identifier_str_mv Archives Of Physical Medicine And Rehabilitation. Philadelphia: W B Saunders Co-elsevier Inc, v. 100, n. 11, p. 2151-2158, 2019.
0003-9993
10.1016/j.apmr.2019.06.006
WOS:000496035600020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Archives Of Physical Medicine And Rehabilitation
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 2151-2158
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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