Dietary whey protein lessens several risk factors for metabolic diseases: a review

• Autor(a) principal: Sousa, Gabriela T. D.
• Data de Publicação: 2012
• Outros Autores: Lira, Fabio S., Rosa, Jose C., de Oliveira, Erick P. [UNESP], Oyama, Lila M., Santos, Ronaldo V., Pimentel, Gustavo D.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1186/1476-511X-11-67; http://hdl.handle.net/11449/13047
• topic: Whey protein; Obesity; Type 2 diabetes mellitus; Appetite; Inflammation; Hypertension

Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies such as dietary manipulation have been widely studied; among them, the whey protein diet has reached popularity because it has been suggested as a strategy for the prevention and treatment of obesity and DM in both humans and animals. Among its main actions, the following activities stand out: reduction of serum glucose in healthy individuals, impaired glucose tolerance in DM and obese patients; reduction in body weight; maintenance of muscle mass; increases in the release of anorectic hormones such as cholecystokinin, leptin, and glucagon like-peptide 1 (GLP-1); and a decrease in the orexigenic hormone ghrelin. Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress.