Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island

Detalhes bibliográficos
Autor(a) principal: Souza Saraiva, Mauro de Mesquita [UNESP]
Data de Publicação: 2020
Outros Autores: Cardoso Gomes de Leon, Candice Maria, Vieira da Silva, Nubia Michelle, Raso, Tania Freitas, Serafini, Patricia Pereira, Naves Givisiez, Patricia Emilia, Gebreyes, Wondwossen Abebe, Bruno de Oliveira, Celso Jose
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1089/mdr.2020.0189
http://hdl.handle.net/11449/197236
Resumo: Aim:Genomic analysis of a methicillin-resistantStaphylococcus aureus(MRSA) strain cultured from a non-migratory seabird at Fernando de Noronha Archipelago (Brazilian oceanic islands) was carried out to investigate the potential origin of MRSA genetic determinants in an ecological setting with minimal or absent antimicrobial selective pressure, and minimal interaction with humans and domestic animals. Results:The study determinedmecA gene homology and the phylogenetic relatedness withmecA described inStaphylococcus sciuri, which was the majorStaphylococcusspp. cultured from the birds. Our findings corroboratein silicoassumptions that themecA gene in MRSA strains clinically relevant for humans and animals originates fromS. sciuriancestors. Conclusion:Coagulase-negative staphylococci seem to be natural reservoirs of methicillin-resistant genes toS. aureus, even in environments with very low antimicrobial selection pressure.
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spelling Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic IslandCoNSmethicillin resistancePhaethontiformesProcellariiformesAim:Genomic analysis of a methicillin-resistantStaphylococcus aureus(MRSA) strain cultured from a non-migratory seabird at Fernando de Noronha Archipelago (Brazilian oceanic islands) was carried out to investigate the potential origin of MRSA genetic determinants in an ecological setting with minimal or absent antimicrobial selective pressure, and minimal interaction with humans and domestic animals. Results:The study determinedmecA gene homology and the phylogenetic relatedness withmecA described inStaphylococcus sciuri, which was the majorStaphylococcusspp. cultured from the birds. Our findings corroboratein silicoassumptions that themecA gene in MRSA strains clinically relevant for humans and animals originates fromS. sciuriancestors. Conclusion:Coagulase-negative staphylococci seem to be natural reservoirs of methicillin-resistant genes toS. aureus, even in environments with very low antimicrobial selection pressure.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Financiadora de Estudos e Projetos (FINEP)Sao Paulo State Univ, Dept Vet Pathol, Lab Ornithopathol, Jaboticabal, BrazilUniv Fed Paraiba, Dept Anim Sci, BR-58397000 Areia, Paraiba, BrazilUniv Sao Paulo, Sch Vet Med & Anim Sci, Dept Pathol, Sao Paulo, BrazilChico Mendes Inst Biodivers Conservat, Natl Ctr Wild Bird Conservat & Res, Florianopolis, SC, BrazilOhio State Univ, Coll Vet Med, Dept Prevent Vet Med, Columbus, OH 43210 USAOhio State Univ, Global One Hlth Initiat, Columbus, OH 43210 USASao Paulo State Univ, Dept Vet Pathol, Lab Ornithopathol, Jaboticabal, BrazilCAPES: 001Mary Ann Liebert, IncUniversidade Estadual Paulista (Unesp)Univ Fed ParaibaUniversidade de São Paulo (USP)Chico Mendes Inst Biodivers ConservatOhio State UnivSouza Saraiva, Mauro de Mesquita [UNESP]Cardoso Gomes de Leon, Candice MariaVieira da Silva, Nubia MichelleRaso, Tania FreitasSerafini, Patricia PereiraNaves Givisiez, Patricia EmiliaGebreyes, Wondwossen AbebeBruno de Oliveira, Celso Jose2020-12-10T20:10:25Z2020-12-10T20:10:25Z2020-08-18info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9http://dx.doi.org/10.1089/mdr.2020.0189Microbial Drug Resistance. New Rochelle: Mary Ann Liebert, Inc, 9 p., 2020.1076-6294http://hdl.handle.net/11449/19723610.1089/mdr.2020.0189WOS:000563458600001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMicrobial Drug Resistanceinfo:eu-repo/semantics/openAccess2024-06-07T13:03:18Zoai:repositorio.unesp.br:11449/197236Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:44:18.869905Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
title Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
spellingShingle Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
Souza Saraiva, Mauro de Mesquita [UNESP]
CoNS
methicillin resistance
Phaethontiformes
Procellariiformes
title_short Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
title_full Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
title_fullStr Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
title_full_unstemmed Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
title_sort Staphylococcus sciurias a Reservoir ofmecA toStaphylococcus aureusin Non-Migratory Seabirds from a Remote Oceanic Island
author Souza Saraiva, Mauro de Mesquita [UNESP]
author_facet Souza Saraiva, Mauro de Mesquita [UNESP]
Cardoso Gomes de Leon, Candice Maria
Vieira da Silva, Nubia Michelle
Raso, Tania Freitas
Serafini, Patricia Pereira
Naves Givisiez, Patricia Emilia
Gebreyes, Wondwossen Abebe
Bruno de Oliveira, Celso Jose
author_role author
author2 Cardoso Gomes de Leon, Candice Maria
Vieira da Silva, Nubia Michelle
Raso, Tania Freitas
Serafini, Patricia Pereira
Naves Givisiez, Patricia Emilia
Gebreyes, Wondwossen Abebe
Bruno de Oliveira, Celso Jose
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Univ Fed Paraiba
Universidade de São Paulo (USP)
Chico Mendes Inst Biodivers Conservat
Ohio State Univ
dc.contributor.author.fl_str_mv Souza Saraiva, Mauro de Mesquita [UNESP]
Cardoso Gomes de Leon, Candice Maria
Vieira da Silva, Nubia Michelle
Raso, Tania Freitas
Serafini, Patricia Pereira
Naves Givisiez, Patricia Emilia
Gebreyes, Wondwossen Abebe
Bruno de Oliveira, Celso Jose
dc.subject.por.fl_str_mv CoNS
methicillin resistance
Phaethontiformes
Procellariiformes
topic CoNS
methicillin resistance
Phaethontiformes
Procellariiformes
description Aim:Genomic analysis of a methicillin-resistantStaphylococcus aureus(MRSA) strain cultured from a non-migratory seabird at Fernando de Noronha Archipelago (Brazilian oceanic islands) was carried out to investigate the potential origin of MRSA genetic determinants in an ecological setting with minimal or absent antimicrobial selective pressure, and minimal interaction with humans and domestic animals. Results:The study determinedmecA gene homology and the phylogenetic relatedness withmecA described inStaphylococcus sciuri, which was the majorStaphylococcusspp. cultured from the birds. Our findings corroboratein silicoassumptions that themecA gene in MRSA strains clinically relevant for humans and animals originates fromS. sciuriancestors. Conclusion:Coagulase-negative staphylococci seem to be natural reservoirs of methicillin-resistant genes toS. aureus, even in environments with very low antimicrobial selection pressure.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-10T20:10:25Z
2020-12-10T20:10:25Z
2020-08-18
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1089/mdr.2020.0189
Microbial Drug Resistance. New Rochelle: Mary Ann Liebert, Inc, 9 p., 2020.
1076-6294
http://hdl.handle.net/11449/197236
10.1089/mdr.2020.0189
WOS:000563458600001
url http://dx.doi.org/10.1089/mdr.2020.0189
http://hdl.handle.net/11449/197236
identifier_str_mv Microbial Drug Resistance. New Rochelle: Mary Ann Liebert, Inc, 9 p., 2020.
1076-6294
10.1089/mdr.2020.0189
WOS:000563458600001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Microbial Drug Resistance
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9
dc.publisher.none.fl_str_mv Mary Ann Liebert, Inc
publisher.none.fl_str_mv Mary Ann Liebert, Inc
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129547855462400

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