Biosynthetic origin of the isoprene units in chromenes of Piper aduncum (Piperaceae)

• Autor(a) principal: Leite, Ana C. [UNESP]
• Data de Publicação: 2007
• Outros Autores: Lopes, Adriana A. [UNESP], Kato, Massuo J., Bolzani, Vanderlan da Silva [UNESP], Furlan, Maysa [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/S0103-50532007000800008; http://hdl.handle.net/11449/70063
• topic: 2-C-methyl-D-erythritol-4-phosphate pathway; [1-13C]-D-glucose; Chromenes; Mevalonate pathway; Piper aduncum

Metabolic studies involving the incorporation of [1-13C]-D- glucose into intact leaves of Piper aduncum (Piperaceae) have indicated that both the mevalonate (MVA) and the pyruvate-triose (MEP) non-mevalonate pathways are implicated in the biosynthesis of isoprene moieties present in methyl 2,2-dimethyl-2H-1-chromene-6-carboxylate (1) and methyl 2,2-dimethyl-8- (3′-methyl-2′-butenyl)-2H-1-chromene-6-carboxylate (2). The pattern of incorporation of label from [1-13C]-D-glucose into these chromenes was determined by quantitative 13C NMR spectroscopy. The results confirmed that biosynthetic compartment of 1 and 2 could either be the plastid and/ or the cytosol or, possibly, an additional compartment such as the plastid inter-membrane space. ©2007 Sociedade Brasileira de Química.