Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov

Detalhes bibliográficos
Autor(a) principal: Silva Filho, Luiz Carlos da [UNESP]
Data de Publicação: 2011
Outros Autores: Frenhe, Mayara [UNESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.orbital.ufms.br/index.php/Chemistry/article/view/205
http://hdl.handle.net/11449/134664
Resumo: The aim of this work was to investigate the use of NbCl5 as Lewis acid in cycloadittion reactions [Reaction Aza-Diels-Alder (Povarov)] between Schiff bases and enol ethers. Comparison of reaction yields, obtained products as well as reaction time with NbCl5 were also a key point on this work. In the aza-Diels-Alder reactions between Schiff bases and enol ethers (dihydropyran or dihydrofuran), the NbCl5 was an excellent catalyst for the synthesis of pyrano- and furanoquinoline derivatives. These derivatives are an important class of natural products that exhibit wide range of biological activity. The reactions were carried out at low concentration of niobium and in relatively short times, resulting in yields varying from 78 to 95%.
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spelling Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de PovarovNiobium pentachloridePovarov reactionsTetrahydroquinoline derivativesAza-Diels-Alder reactionsThe aim of this work was to investigate the use of NbCl5 as Lewis acid in cycloadittion reactions [Reaction Aza-Diels-Alder (Povarov)] between Schiff bases and enol ethers. Comparison of reaction yields, obtained products as well as reaction time with NbCl5 were also a key point on this work. In the aza-Diels-Alder reactions between Schiff bases and enol ethers (dihydropyran or dihydrofuran), the NbCl5 was an excellent catalyst for the synthesis of pyrano- and furanoquinoline derivatives. These derivatives are an important class of natural products that exhibit wide range of biological activity. The reactions were carried out at low concentration of niobium and in relatively short times, resulting in yields varying from 78 to 95%.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências (FC), Departamento de Química, Bauru, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências (FC), Departamento de Química, Bauru, SP, BrasilUniversidade Estadual Paulista (Unesp)Silva Filho, Luiz Carlos da [UNESP]Frenhe, Mayara [UNESP]2016-03-02T12:57:52Z2016-03-02T12:57:52Z2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-14application/pdfhttp://www.orbital.ufms.br/index.php/Chemistry/article/view/205Orbital: the Electronic Journal of Chemistry, v. 3, n. 1, p. 1-14, 2011.1984-6428http://hdl.handle.net/11449/134664ISSN1984-6428-2011-03-01-01-14.pdf92316085539512929154336767369306Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporOrbital: the Electronic Journal of Chemistryinfo:eu-repo/semantics/openAccess2024-04-29T18:17:11Zoai:repositorio.unesp.br:11449/134664Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:31:17.005088Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
title Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
spellingShingle Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
Silva Filho, Luiz Carlos da [UNESP]
Niobium pentachloride
Povarov reactions
Tetrahydroquinoline derivatives
Aza-Diels-Alder reactions
title_short Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
title_full Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
title_fullStr Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
title_full_unstemmed Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
title_sort Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
author Silva Filho, Luiz Carlos da [UNESP]
author_facet Silva Filho, Luiz Carlos da [UNESP]
Frenhe, Mayara [UNESP]
author_role author
author2 Frenhe, Mayara [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Silva Filho, Luiz Carlos da [UNESP]
Frenhe, Mayara [UNESP]
dc.subject.por.fl_str_mv Niobium pentachloride
Povarov reactions
Tetrahydroquinoline derivatives
Aza-Diels-Alder reactions
topic Niobium pentachloride
Povarov reactions
Tetrahydroquinoline derivatives
Aza-Diels-Alder reactions
description The aim of this work was to investigate the use of NbCl5 as Lewis acid in cycloadittion reactions [Reaction Aza-Diels-Alder (Povarov)] between Schiff bases and enol ethers. Comparison of reaction yields, obtained products as well as reaction time with NbCl5 were also a key point on this work. In the aza-Diels-Alder reactions between Schiff bases and enol ethers (dihydropyran or dihydrofuran), the NbCl5 was an excellent catalyst for the synthesis of pyrano- and furanoquinoline derivatives. These derivatives are an important class of natural products that exhibit wide range of biological activity. The reactions were carried out at low concentration of niobium and in relatively short times, resulting in yields varying from 78 to 95%.
publishDate 2011
dc.date.none.fl_str_mv 2011
2016-03-02T12:57:52Z
2016-03-02T12:57:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.orbital.ufms.br/index.php/Chemistry/article/view/205
Orbital: the Electronic Journal of Chemistry, v. 3, n. 1, p. 1-14, 2011.
1984-6428
http://hdl.handle.net/11449/134664
ISSN1984-6428-2011-03-01-01-14.pdf
9231608553951292
9154336767369306
url http://www.orbital.ufms.br/index.php/Chemistry/article/view/205
http://hdl.handle.net/11449/134664
identifier_str_mv Orbital: the Electronic Journal of Chemistry, v. 3, n. 1, p. 1-14, 2011.
1984-6428
ISSN1984-6428-2011-03-01-01-14.pdf
9231608553951292
9154336767369306
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Orbital: the Electronic Journal of Chemistry
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-14
application/pdf
dc.source.none.fl_str_mv Currículo Lattes
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129081258016768

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