Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice

Detalhes bibliográficos
Autor(a) principal: Crestani, Ariela M. [UNESP]
Data de Publicação: 2018
Outros Autores: Cipriano, Ana C. [UNESP], Nunes-de-Souza, Ricardo L. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.beproc.2018.04.010
http://hdl.handle.net/11449/176208
Resumo: Aggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context.
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spelling Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in miceContextual conditioningContextual memorySelf-groomingSocial defeatAggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Natural Active Principlesand Toxicology School of Pharmaceutical Sciences São Paulo State University – UNESPJoint Graduate Program in Physiological Sciences UFSCar/UNESPDepartment of Natural Active Principlesand Toxicology School of Pharmaceutical Sciences São Paulo State University – UNESPJoint Graduate Program in Physiological Sciences UFSCar/UNESPCNPq: 131661/2013-2FAPESP: 2011/04561-1FAPESP: 2013/01383-6CNPq: 306556/2015-4CNPq: 478696/2013-2Universidade Estadual Paulista (Unesp)Crestani, Ariela M. [UNESP]Cipriano, Ana C. [UNESP]Nunes-de-Souza, Ricardo L. [UNESP]2018-12-11T17:19:36Z2018-12-11T17:19:36Z2018-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.beproc.2018.04.010Behavioural Processes.1872-83080376-6357http://hdl.handle.net/11449/17620810.1016/j.beproc.2018.04.0102-s2.0-850457465002-s2.0-85045746500.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBehavioural Processes0,849info:eu-repo/semantics/openAccess2024-06-24T14:51:52Zoai:repositorio.unesp.br:11449/176208Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:22:13.919626Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
title Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
spellingShingle Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
Crestani, Ariela M. [UNESP]
Contextual conditioning
Contextual memory
Self-grooming
Social defeat
title_short Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
title_full Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
title_fullStr Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
title_full_unstemmed Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
title_sort Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
author Crestani, Ariela M. [UNESP]
author_facet Crestani, Ariela M. [UNESP]
Cipriano, Ana C. [UNESP]
Nunes-de-Souza, Ricardo L. [UNESP]
author_role author
author2 Cipriano, Ana C. [UNESP]
Nunes-de-Souza, Ricardo L. [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Crestani, Ariela M. [UNESP]
Cipriano, Ana C. [UNESP]
Nunes-de-Souza, Ricardo L. [UNESP]
dc.subject.por.fl_str_mv Contextual conditioning
Contextual memory
Self-grooming
Social defeat
topic Contextual conditioning
Contextual memory
Self-grooming
Social defeat
description Aggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-11T17:19:36Z
2018-12-11T17:19:36Z
2018-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.beproc.2018.04.010
Behavioural Processes.
1872-8308
0376-6357
http://hdl.handle.net/11449/176208
10.1016/j.beproc.2018.04.010
2-s2.0-85045746500
2-s2.0-85045746500.pdf
url http://dx.doi.org/10.1016/j.beproc.2018.04.010
http://hdl.handle.net/11449/176208
identifier_str_mv Behavioural Processes.
1872-8308
0376-6357
10.1016/j.beproc.2018.04.010
2-s2.0-85045746500
2-s2.0-85045746500.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Behavioural Processes
0,849
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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