Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.beproc.2018.04.010 http://hdl.handle.net/11449/176208 |
Resumo: | Aggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context. |
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Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in miceContextual conditioningContextual memorySelf-groomingSocial defeatAggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Natural Active Principlesand Toxicology School of Pharmaceutical Sciences São Paulo State University – UNESPJoint Graduate Program in Physiological Sciences UFSCar/UNESPDepartment of Natural Active Principlesand Toxicology School of Pharmaceutical Sciences São Paulo State University – UNESPJoint Graduate Program in Physiological Sciences UFSCar/UNESPCNPq: 131661/2013-2FAPESP: 2011/04561-1FAPESP: 2013/01383-6CNPq: 306556/2015-4CNPq: 478696/2013-2Universidade Estadual Paulista (Unesp)Crestani, Ariela M. [UNESP]Cipriano, Ana C. [UNESP]Nunes-de-Souza, Ricardo L. [UNESP]2018-12-11T17:19:36Z2018-12-11T17:19:36Z2018-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1016/j.beproc.2018.04.010Behavioural Processes.1872-83080376-6357http://hdl.handle.net/11449/17620810.1016/j.beproc.2018.04.0102-s2.0-850457465002-s2.0-85045746500.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBehavioural Processes0,849info:eu-repo/semantics/openAccess2024-06-24T14:51:52Zoai:repositorio.unesp.br:11449/176208Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:22:13.919626Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice |
title |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice |
spellingShingle |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice Crestani, Ariela M. [UNESP] Contextual conditioning Contextual memory Self-grooming Social defeat |
title_short |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice |
title_full |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice |
title_fullStr |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice |
title_full_unstemmed |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice |
title_sort |
Single aggressive and non-aggressive social interactions elicit distinct behavioral patterns to the context in mice |
author |
Crestani, Ariela M. [UNESP] |
author_facet |
Crestani, Ariela M. [UNESP] Cipriano, Ana C. [UNESP] Nunes-de-Souza, Ricardo L. [UNESP] |
author_role |
author |
author2 |
Cipriano, Ana C. [UNESP] Nunes-de-Souza, Ricardo L. [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Crestani, Ariela M. [UNESP] Cipriano, Ana C. [UNESP] Nunes-de-Souza, Ricardo L. [UNESP] |
dc.subject.por.fl_str_mv |
Contextual conditioning Contextual memory Self-grooming Social defeat |
topic |
Contextual conditioning Contextual memory Self-grooming Social defeat |
description |
Aggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-11T17:19:36Z 2018-12-11T17:19:36Z 2018-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.beproc.2018.04.010 Behavioural Processes. 1872-8308 0376-6357 http://hdl.handle.net/11449/176208 10.1016/j.beproc.2018.04.010 2-s2.0-85045746500 2-s2.0-85045746500.pdf |
url |
http://dx.doi.org/10.1016/j.beproc.2018.04.010 http://hdl.handle.net/11449/176208 |
identifier_str_mv |
Behavioural Processes. 1872-8308 0376-6357 10.1016/j.beproc.2018.04.010 2-s2.0-85045746500 2-s2.0-85045746500.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Behavioural Processes 0,849 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129060131307520 |