Propofol and benzocaine anesthetics responses profiles in Nile Tilapia

Detalhes bibliográficos
Autor(a) principal: Gonçalves, Bruno Bastos
Data de Publicação: 2020
Outros Autores: Giaquinto, Percília Cardoso [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.22034/iar.2020.1895923.1026
http://hdl.handle.net/11449/208043
Resumo: Improving welfare in fish requires avoiding pain, stress and suffering. Propofol, 2,6diisopropylphenol, seems to be a good candidate as a fish anaesthetic, however, no study regarding propofol influence on Nile tilapia has yet been reported. With this aim, the efficiency of propofol and benzocaine was compared as anesthetic for fish following immersion exposure. Nile tilapia (Oreochromis niloticus) was used as model due its importance in aquaculture, been the most important fish for human consumption, where 4.5 million tonnes of fish are produced worldwide. At first, determination of effective anaesthetic concentrations to induce complete anesthesia was determined, under immersion, considering time to start decubitus stage. Then the magnitude of these anesthetics was tested, measuring its effects on time remaining in decubitus, posture recovery, ventilatory frequency (VF) and latency to feed. Benzocaine induced reduction of VF under decubitus. After the anesthetic effects, VF returned quickly to basal levels. The same pattern was observed for propofol, however with no return to basal levels after recovery. Time to start decubitus was similar in both anesthetic, but time to return was higher in propofol. The latency to feed was longer in fishes submitted to propofol. Thus, propofol is a more powerful anesthetic than benzocaine in Nile tilapia, with longer duration and deeper effect. Although the common usage of propofol is by intravenous injection, here we show that immersion is efficient as an anesthetic in fish and could be adopted as a protocol in experimentation as well aquaculture management. Analgesia in fish is an area in need of significant research as only a few studies exist and they provide some contrasting results.
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spelling Propofol and benzocaine anesthetics responses profiles in Nile TilapiaAnesthesiaAnimal welfareAquacultureManagementOreochromis niloticusVentilatory frequencyImproving welfare in fish requires avoiding pain, stress and suffering. Propofol, 2,6diisopropylphenol, seems to be a good candidate as a fish anaesthetic, however, no study regarding propofol influence on Nile tilapia has yet been reported. With this aim, the efficiency of propofol and benzocaine was compared as anesthetic for fish following immersion exposure. Nile tilapia (Oreochromis niloticus) was used as model due its importance in aquaculture, been the most important fish for human consumption, where 4.5 million tonnes of fish are produced worldwide. At first, determination of effective anaesthetic concentrations to induce complete anesthesia was determined, under immersion, considering time to start decubitus stage. Then the magnitude of these anesthetics was tested, measuring its effects on time remaining in decubitus, posture recovery, ventilatory frequency (VF) and latency to feed. Benzocaine induced reduction of VF under decubitus. After the anesthetic effects, VF returned quickly to basal levels. The same pattern was observed for propofol, however with no return to basal levels after recovery. Time to start decubitus was similar in both anesthetic, but time to return was higher in propofol. The latency to feed was longer in fishes submitted to propofol. Thus, propofol is a more powerful anesthetic than benzocaine in Nile tilapia, with longer duration and deeper effect. Although the common usage of propofol is by intravenous injection, here we show that immersion is efficient as an anesthetic in fish and could be adopted as a protocol in experimentation as well aquaculture management. Analgesia in fish is an area in need of significant research as only a few studies exist and they provide some contrasting results.Laboratory of Environmental Biotechnology and Ecotoxicology Institute of Tropical Pathology and Public Health of UFG Goiás Federal UniversityGiaquinto Physiology Department Bioscience Institute São Paulo State University UNESPGiaquinto Physiology Department Bioscience Institute São Paulo State University UNESPGoiás Federal UniversityUniversidade Estadual Paulista (Unesp)Gonçalves, Bruno BastosGiaquinto, Percília Cardoso [UNESP]2021-06-25T11:05:21Z2021-06-25T11:05:21Z2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article219-225http://dx.doi.org/10.22034/iar.2020.1895923.1026International Aquatic Research, v. 12, n. 3, p. 219-225, 2020.2008-69702008-4935http://hdl.handle.net/11449/20804310.22034/iar.2020.1895923.10262-s2.0-85092589984Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Aquatic Researchinfo:eu-repo/semantics/openAccess2021-10-22T20:36:23Zoai:repositorio.unesp.br:11449/208043Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-22T20:36:23Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
title Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
spellingShingle Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
Gonçalves, Bruno Bastos
Anesthesia
Animal welfare
Aquaculture
Management
Oreochromis niloticus
Ventilatory frequency
title_short Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
title_full Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
title_fullStr Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
title_full_unstemmed Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
title_sort Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
author Gonçalves, Bruno Bastos
author_facet Gonçalves, Bruno Bastos
Giaquinto, Percília Cardoso [UNESP]
author_role author
author2 Giaquinto, Percília Cardoso [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Goiás Federal University
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Gonçalves, Bruno Bastos
Giaquinto, Percília Cardoso [UNESP]
dc.subject.por.fl_str_mv Anesthesia
Animal welfare
Aquaculture
Management
Oreochromis niloticus
Ventilatory frequency
topic Anesthesia
Animal welfare
Aquaculture
Management
Oreochromis niloticus
Ventilatory frequency
description Improving welfare in fish requires avoiding pain, stress and suffering. Propofol, 2,6diisopropylphenol, seems to be a good candidate as a fish anaesthetic, however, no study regarding propofol influence on Nile tilapia has yet been reported. With this aim, the efficiency of propofol and benzocaine was compared as anesthetic for fish following immersion exposure. Nile tilapia (Oreochromis niloticus) was used as model due its importance in aquaculture, been the most important fish for human consumption, where 4.5 million tonnes of fish are produced worldwide. At first, determination of effective anaesthetic concentrations to induce complete anesthesia was determined, under immersion, considering time to start decubitus stage. Then the magnitude of these anesthetics was tested, measuring its effects on time remaining in decubitus, posture recovery, ventilatory frequency (VF) and latency to feed. Benzocaine induced reduction of VF under decubitus. After the anesthetic effects, VF returned quickly to basal levels. The same pattern was observed for propofol, however with no return to basal levels after recovery. Time to start decubitus was similar in both anesthetic, but time to return was higher in propofol. The latency to feed was longer in fishes submitted to propofol. Thus, propofol is a more powerful anesthetic than benzocaine in Nile tilapia, with longer duration and deeper effect. Although the common usage of propofol is by intravenous injection, here we show that immersion is efficient as an anesthetic in fish and could be adopted as a protocol in experimentation as well aquaculture management. Analgesia in fish is an area in need of significant research as only a few studies exist and they provide some contrasting results.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-01
2021-06-25T11:05:21Z
2021-06-25T11:05:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.22034/iar.2020.1895923.1026
International Aquatic Research, v. 12, n. 3, p. 219-225, 2020.
2008-6970
2008-4935
http://hdl.handle.net/11449/208043
10.22034/iar.2020.1895923.1026
2-s2.0-85092589984
url http://dx.doi.org/10.22034/iar.2020.1895923.1026
http://hdl.handle.net/11449/208043
identifier_str_mv International Aquatic Research, v. 12, n. 3, p. 219-225, 2020.
2008-6970
2008-4935
10.22034/iar.2020.1895923.1026
2-s2.0-85092589984
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Aquatic Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 219-225
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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