Propofol and benzocaine anesthetics responses profiles in Nile Tilapia
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.22034/iar.2020.1895923.1026 http://hdl.handle.net/11449/208043 |
Resumo: | Improving welfare in fish requires avoiding pain, stress and suffering. Propofol, 2,6diisopropylphenol, seems to be a good candidate as a fish anaesthetic, however, no study regarding propofol influence on Nile tilapia has yet been reported. With this aim, the efficiency of propofol and benzocaine was compared as anesthetic for fish following immersion exposure. Nile tilapia (Oreochromis niloticus) was used as model due its importance in aquaculture, been the most important fish for human consumption, where 4.5 million tonnes of fish are produced worldwide. At first, determination of effective anaesthetic concentrations to induce complete anesthesia was determined, under immersion, considering time to start decubitus stage. Then the magnitude of these anesthetics was tested, measuring its effects on time remaining in decubitus, posture recovery, ventilatory frequency (VF) and latency to feed. Benzocaine induced reduction of VF under decubitus. After the anesthetic effects, VF returned quickly to basal levels. The same pattern was observed for propofol, however with no return to basal levels after recovery. Time to start decubitus was similar in both anesthetic, but time to return was higher in propofol. The latency to feed was longer in fishes submitted to propofol. Thus, propofol is a more powerful anesthetic than benzocaine in Nile tilapia, with longer duration and deeper effect. Although the common usage of propofol is by intravenous injection, here we show that immersion is efficient as an anesthetic in fish and could be adopted as a protocol in experimentation as well aquaculture management. Analgesia in fish is an area in need of significant research as only a few studies exist and they provide some contrasting results. |
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Propofol and benzocaine anesthetics responses profiles in Nile TilapiaAnesthesiaAnimal welfareAquacultureManagementOreochromis niloticusVentilatory frequencyImproving welfare in fish requires avoiding pain, stress and suffering. Propofol, 2,6diisopropylphenol, seems to be a good candidate as a fish anaesthetic, however, no study regarding propofol influence on Nile tilapia has yet been reported. With this aim, the efficiency of propofol and benzocaine was compared as anesthetic for fish following immersion exposure. Nile tilapia (Oreochromis niloticus) was used as model due its importance in aquaculture, been the most important fish for human consumption, where 4.5 million tonnes of fish are produced worldwide. At first, determination of effective anaesthetic concentrations to induce complete anesthesia was determined, under immersion, considering time to start decubitus stage. Then the magnitude of these anesthetics was tested, measuring its effects on time remaining in decubitus, posture recovery, ventilatory frequency (VF) and latency to feed. Benzocaine induced reduction of VF under decubitus. After the anesthetic effects, VF returned quickly to basal levels. The same pattern was observed for propofol, however with no return to basal levels after recovery. Time to start decubitus was similar in both anesthetic, but time to return was higher in propofol. The latency to feed was longer in fishes submitted to propofol. Thus, propofol is a more powerful anesthetic than benzocaine in Nile tilapia, with longer duration and deeper effect. Although the common usage of propofol is by intravenous injection, here we show that immersion is efficient as an anesthetic in fish and could be adopted as a protocol in experimentation as well aquaculture management. Analgesia in fish is an area in need of significant research as only a few studies exist and they provide some contrasting results.Laboratory of Environmental Biotechnology and Ecotoxicology Institute of Tropical Pathology and Public Health of UFG Goiás Federal UniversityGiaquinto Physiology Department Bioscience Institute São Paulo State University UNESPGiaquinto Physiology Department Bioscience Institute São Paulo State University UNESPGoiás Federal UniversityUniversidade Estadual Paulista (Unesp)Gonçalves, Bruno BastosGiaquinto, Percília Cardoso [UNESP]2021-06-25T11:05:21Z2021-06-25T11:05:21Z2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article219-225http://dx.doi.org/10.22034/iar.2020.1895923.1026International Aquatic Research, v. 12, n. 3, p. 219-225, 2020.2008-69702008-4935http://hdl.handle.net/11449/20804310.22034/iar.2020.1895923.10262-s2.0-85092589984Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Aquatic Researchinfo:eu-repo/semantics/openAccess2021-10-22T20:36:23Zoai:repositorio.unesp.br:11449/208043Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-22T20:36:23Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia |
title |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia |
spellingShingle |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia Gonçalves, Bruno Bastos Anesthesia Animal welfare Aquaculture Management Oreochromis niloticus Ventilatory frequency |
title_short |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia |
title_full |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia |
title_fullStr |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia |
title_full_unstemmed |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia |
title_sort |
Propofol and benzocaine anesthetics responses profiles in Nile Tilapia |
author |
Gonçalves, Bruno Bastos |
author_facet |
Gonçalves, Bruno Bastos Giaquinto, Percília Cardoso [UNESP] |
author_role |
author |
author2 |
Giaquinto, Percília Cardoso [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Goiás Federal University Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Gonçalves, Bruno Bastos Giaquinto, Percília Cardoso [UNESP] |
dc.subject.por.fl_str_mv |
Anesthesia Animal welfare Aquaculture Management Oreochromis niloticus Ventilatory frequency |
topic |
Anesthesia Animal welfare Aquaculture Management Oreochromis niloticus Ventilatory frequency |
description |
Improving welfare in fish requires avoiding pain, stress and suffering. Propofol, 2,6diisopropylphenol, seems to be a good candidate as a fish anaesthetic, however, no study regarding propofol influence on Nile tilapia has yet been reported. With this aim, the efficiency of propofol and benzocaine was compared as anesthetic for fish following immersion exposure. Nile tilapia (Oreochromis niloticus) was used as model due its importance in aquaculture, been the most important fish for human consumption, where 4.5 million tonnes of fish are produced worldwide. At first, determination of effective anaesthetic concentrations to induce complete anesthesia was determined, under immersion, considering time to start decubitus stage. Then the magnitude of these anesthetics was tested, measuring its effects on time remaining in decubitus, posture recovery, ventilatory frequency (VF) and latency to feed. Benzocaine induced reduction of VF under decubitus. After the anesthetic effects, VF returned quickly to basal levels. The same pattern was observed for propofol, however with no return to basal levels after recovery. Time to start decubitus was similar in both anesthetic, but time to return was higher in propofol. The latency to feed was longer in fishes submitted to propofol. Thus, propofol is a more powerful anesthetic than benzocaine in Nile tilapia, with longer duration and deeper effect. Although the common usage of propofol is by intravenous injection, here we show that immersion is efficient as an anesthetic in fish and could be adopted as a protocol in experimentation as well aquaculture management. Analgesia in fish is an area in need of significant research as only a few studies exist and they provide some contrasting results. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-09-01 2021-06-25T11:05:21Z 2021-06-25T11:05:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.22034/iar.2020.1895923.1026 International Aquatic Research, v. 12, n. 3, p. 219-225, 2020. 2008-6970 2008-4935 http://hdl.handle.net/11449/208043 10.22034/iar.2020.1895923.1026 2-s2.0-85092589984 |
url |
http://dx.doi.org/10.22034/iar.2020.1895923.1026 http://hdl.handle.net/11449/208043 |
identifier_str_mv |
International Aquatic Research, v. 12, n. 3, p. 219-225, 2020. 2008-6970 2008-4935 10.22034/iar.2020.1895923.1026 2-s2.0-85092589984 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Aquatic Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
219-225 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964569467092992 |