Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.diabres.2015.10.025 http://hdl.handle.net/11449/177779 |
Resumo: | Objective: The aim of this study was to evaluate: (1) the cardiovascular parameters and plasma biomarkers in people with type 1 diabetes mellitus (T1DM) at baseline; and (2) the heart rate variability (HRV) and blood glucose in response to a session of aerobic exercise (AE) and during recovery period. Research design and methods: Adults (18-35 years) were divided into two groups: control (CT, n = 10) and T1DM (n = 9). Anthropometric, cardiovascular, and biochemical parameters, and aerobic capacity (indirect peak oxygen uptake, VO2peak) were evaluated at baseline. Thirty minutes of AE (40-60% intensity) was performed on a treadmill. Blood glucose and HRV were determined at rest, during AE, and during the recovery period. Results: Anthropometric measurements, cardiovascular parameters, aerobic capacity, and biochemical parameters were similar between the groups at baseline. In the T1DM group, blood glucose, glycated hemoglobin, and thiobarbituric acid reactive substances concentrations were increased while nitrite/nitrate (NOx -) levels were reduced. During AE, the magnitude of the reduction of blood glucose was greater than that during the recovery period in the T1DM group. The RR intervals and SDNN were reduced at rest as well as in the recovery period in T1DM subjects, whereas the RMSSD and pNN50 were only reduced during the recovery period. No changes were observed in low frequency (LF), high frequency (HF), and LF/HF ratio. Conclusion: Our study shows that T1DM patients on insulin therapy have poor blood glucose control with greater lipid peroxidation and lower NOx - levels, accompanied by an imbalance in autonomic function detected by the challenge of AE. |
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Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exerciseAcute aerobic exerciseBlood glucoseHeart rate variabilityNOx -Thiobarbituric acid reactive substances (TBARS)Type 1 diabetes mellitusObjective: The aim of this study was to evaluate: (1) the cardiovascular parameters and plasma biomarkers in people with type 1 diabetes mellitus (T1DM) at baseline; and (2) the heart rate variability (HRV) and blood glucose in response to a session of aerobic exercise (AE) and during recovery period. Research design and methods: Adults (18-35 years) were divided into two groups: control (CT, n = 10) and T1DM (n = 9). Anthropometric, cardiovascular, and biochemical parameters, and aerobic capacity (indirect peak oxygen uptake, VO2peak) were evaluated at baseline. Thirty minutes of AE (40-60% intensity) was performed on a treadmill. Blood glucose and HRV were determined at rest, during AE, and during the recovery period. Results: Anthropometric measurements, cardiovascular parameters, aerobic capacity, and biochemical parameters were similar between the groups at baseline. In the T1DM group, blood glucose, glycated hemoglobin, and thiobarbituric acid reactive substances concentrations were increased while nitrite/nitrate (NOx -) levels were reduced. During AE, the magnitude of the reduction of blood glucose was greater than that during the recovery period in the T1DM group. The RR intervals and SDNN were reduced at rest as well as in the recovery period in T1DM subjects, whereas the RMSSD and pNN50 were only reduced during the recovery period. No changes were observed in low frequency (LF), high frequency (HF), and LF/HF ratio. Conclusion: Our study shows that T1DM patients on insulin therapy have poor blood glucose control with greater lipid peroxidation and lower NOx - levels, accompanied by an imbalance in autonomic function detected by the challenge of AE.Department of Physical Education Institute of Biosciences UNESP - Univ Estadual PaulistaDepartment of Structural and Functional Biology Institute of Biology UNICAMP - University of CampinasDepartment of Physical Education Institute of Biosciences UNESP - Univ Estadual PaulistaUniversidade Estadual Paulista (Unesp)Universidade Estadual de Campinas (UNICAMP)Anaruma, Chadi P. [UNESP]Ferreira, Maycon [UNESP]Sponton, Carlos H.G. [UNESP]Delbin, Maria A.Zanesco, Angelina [UNESP]2018-12-11T17:27:05Z2018-12-11T17:27:05Z2016-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article19-27application/pdfhttp://dx.doi.org/10.1016/j.diabres.2015.10.025Diabetes Research and Clinical Practice, v. 111, p. 19-27.1872-82270168-8227http://hdl.handle.net/11449/17777910.1016/j.diabres.2015.10.0252-s2.0-849575513972-s2.0-84957551397.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengDiabetes Research and Clinical Practice1,538info:eu-repo/semantics/openAccess2023-10-10T06:06:29Zoai:repositorio.unesp.br:11449/177779Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:31:45.021427Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise |
title |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise |
spellingShingle |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise Anaruma, Chadi P. [UNESP] Acute aerobic exercise Blood glucose Heart rate variability NOx - Thiobarbituric acid reactive substances (TBARS) Type 1 diabetes mellitus |
title_short |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise |
title_full |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise |
title_fullStr |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise |
title_full_unstemmed |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise |
title_sort |
Heart rate variability and plasma biomarkers in patients with type 1 diabetes mellitus: Effect of a bout of aerobic exercise |
author |
Anaruma, Chadi P. [UNESP] |
author_facet |
Anaruma, Chadi P. [UNESP] Ferreira, Maycon [UNESP] Sponton, Carlos H.G. [UNESP] Delbin, Maria A. Zanesco, Angelina [UNESP] |
author_role |
author |
author2 |
Ferreira, Maycon [UNESP] Sponton, Carlos H.G. [UNESP] Delbin, Maria A. Zanesco, Angelina [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Estadual de Campinas (UNICAMP) |
dc.contributor.author.fl_str_mv |
Anaruma, Chadi P. [UNESP] Ferreira, Maycon [UNESP] Sponton, Carlos H.G. [UNESP] Delbin, Maria A. Zanesco, Angelina [UNESP] |
dc.subject.por.fl_str_mv |
Acute aerobic exercise Blood glucose Heart rate variability NOx - Thiobarbituric acid reactive substances (TBARS) Type 1 diabetes mellitus |
topic |
Acute aerobic exercise Blood glucose Heart rate variability NOx - Thiobarbituric acid reactive substances (TBARS) Type 1 diabetes mellitus |
description |
Objective: The aim of this study was to evaluate: (1) the cardiovascular parameters and plasma biomarkers in people with type 1 diabetes mellitus (T1DM) at baseline; and (2) the heart rate variability (HRV) and blood glucose in response to a session of aerobic exercise (AE) and during recovery period. Research design and methods: Adults (18-35 years) were divided into two groups: control (CT, n = 10) and T1DM (n = 9). Anthropometric, cardiovascular, and biochemical parameters, and aerobic capacity (indirect peak oxygen uptake, VO2peak) were evaluated at baseline. Thirty minutes of AE (40-60% intensity) was performed on a treadmill. Blood glucose and HRV were determined at rest, during AE, and during the recovery period. Results: Anthropometric measurements, cardiovascular parameters, aerobic capacity, and biochemical parameters were similar between the groups at baseline. In the T1DM group, blood glucose, glycated hemoglobin, and thiobarbituric acid reactive substances concentrations were increased while nitrite/nitrate (NOx -) levels were reduced. During AE, the magnitude of the reduction of blood glucose was greater than that during the recovery period in the T1DM group. The RR intervals and SDNN were reduced at rest as well as in the recovery period in T1DM subjects, whereas the RMSSD and pNN50 were only reduced during the recovery period. No changes were observed in low frequency (LF), high frequency (HF), and LF/HF ratio. Conclusion: Our study shows that T1DM patients on insulin therapy have poor blood glucose control with greater lipid peroxidation and lower NOx - levels, accompanied by an imbalance in autonomic function detected by the challenge of AE. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-01-01 2018-12-11T17:27:05Z 2018-12-11T17:27:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.diabres.2015.10.025 Diabetes Research and Clinical Practice, v. 111, p. 19-27. 1872-8227 0168-8227 http://hdl.handle.net/11449/177779 10.1016/j.diabres.2015.10.025 2-s2.0-84957551397 2-s2.0-84957551397.pdf |
url |
http://dx.doi.org/10.1016/j.diabres.2015.10.025 http://hdl.handle.net/11449/177779 |
identifier_str_mv |
Diabetes Research and Clinical Practice, v. 111, p. 19-27. 1872-8227 0168-8227 10.1016/j.diabres.2015.10.025 2-s2.0-84957551397 2-s2.0-84957551397.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Diabetes Research and Clinical Practice 1,538 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
19-27 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128374858579968 |