Birth defects: Risk factors and consequences
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3233/PGE-13052 http://hdl.handle.net/11449/228288 |
Resumo: | Birth defects (BDs) or congenital anomalies include all structural and functional alterations in embryonic or fetal development resulting from genetic, environmental or unknown causes, which result in physical and/or mental impairment. BDs occur in about 3% of newborn babies and in most cases of pregnancy loss. BDs are a very complex and heterogeneous group of single or multiple changes that, in most cases, are of unknown etiology. Among the risk factors are advanced maternal and paternal ages, parental consanguinity, teratogenic agents such as infectious agents and drugs, and poor nutrition, in particular folic acid deficiency. One of the consequences of these defects is the high death rate within the first year of life. Information on BDs is becoming increasingly more important throughout the world so that preventive measures can be taken. Knowledge of BDs enables the development of therapeutic and preventive strategies besides adequate genetic counseling. © 2013 - IOS Press and the authors. |
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Birth defects: Risk factors and consequencesChromosomal abnormalitiesCongenital anomaliesCongenital malformationBirth defects (BDs) or congenital anomalies include all structural and functional alterations in embryonic or fetal development resulting from genetic, environmental or unknown causes, which result in physical and/or mental impairment. BDs occur in about 3% of newborn babies and in most cases of pregnancy loss. BDs are a very complex and heterogeneous group of single or multiple changes that, in most cases, are of unknown etiology. Among the risk factors are advanced maternal and paternal ages, parental consanguinity, teratogenic agents such as infectious agents and drugs, and poor nutrition, in particular folic acid deficiency. One of the consequences of these defects is the high death rate within the first year of life. Information on BDs is becoming increasingly more important throughout the world so that preventive measures can be taken. Knowledge of BDs enables the development of therapeutic and preventive strategies besides adequate genetic counseling. © 2013 - IOS Press and the authors.Department of Biology Institute of Biosciences Letters and Science (IBILCE) Paulista State University Júlio de Mesquita Filho, São José do Rio Preto, SPDepartment of Molecular Biology Medicine School of São José do Rio Preto, São José do Rio Preto, SPDepartment of Biology Institute of Biosciences Letters and Science (IBILCE) Paulista State University Júlio de Mesquita Filho, São José do Rio Preto, SPUniversidade Estadual Paulista (UNESP)Medicine School of São José do Rio PretoOliveira, Camila Ive Ferreira [UNESP]Fett-Conte, Agnes Cristina2022-04-29T08:00:15Z2022-04-29T08:00:15Z2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article85-90http://dx.doi.org/10.3233/PGE-13052Journal of Pediatric Genetics, v. 2, n. 2, p. 85-90, 2013.2146-460X2146-4596http://hdl.handle.net/11449/22828810.3233/PGE-130522-s2.0-85013578705Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Pediatric Geneticsinfo:eu-repo/semantics/openAccess2022-04-29T08:00:15Zoai:repositorio.unesp.br:11449/228288Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-29T08:00:15Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Birth defects: Risk factors and consequences |
title |
Birth defects: Risk factors and consequences |
spellingShingle |
Birth defects: Risk factors and consequences Oliveira, Camila Ive Ferreira [UNESP] Chromosomal abnormalities Congenital anomalies Congenital malformation |
title_short |
Birth defects: Risk factors and consequences |
title_full |
Birth defects: Risk factors and consequences |
title_fullStr |
Birth defects: Risk factors and consequences |
title_full_unstemmed |
Birth defects: Risk factors and consequences |
title_sort |
Birth defects: Risk factors and consequences |
author |
Oliveira, Camila Ive Ferreira [UNESP] |
author_facet |
Oliveira, Camila Ive Ferreira [UNESP] Fett-Conte, Agnes Cristina |
author_role |
author |
author2 |
Fett-Conte, Agnes Cristina |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Medicine School of São José do Rio Preto |
dc.contributor.author.fl_str_mv |
Oliveira, Camila Ive Ferreira [UNESP] Fett-Conte, Agnes Cristina |
dc.subject.por.fl_str_mv |
Chromosomal abnormalities Congenital anomalies Congenital malformation |
topic |
Chromosomal abnormalities Congenital anomalies Congenital malformation |
description |
Birth defects (BDs) or congenital anomalies include all structural and functional alterations in embryonic or fetal development resulting from genetic, environmental or unknown causes, which result in physical and/or mental impairment. BDs occur in about 3% of newborn babies and in most cases of pregnancy loss. BDs are a very complex and heterogeneous group of single or multiple changes that, in most cases, are of unknown etiology. Among the risk factors are advanced maternal and paternal ages, parental consanguinity, teratogenic agents such as infectious agents and drugs, and poor nutrition, in particular folic acid deficiency. One of the consequences of these defects is the high death rate within the first year of life. Information on BDs is becoming increasingly more important throughout the world so that preventive measures can be taken. Knowledge of BDs enables the development of therapeutic and preventive strategies besides adequate genetic counseling. © 2013 - IOS Press and the authors. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-01 2022-04-29T08:00:15Z 2022-04-29T08:00:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3233/PGE-13052 Journal of Pediatric Genetics, v. 2, n. 2, p. 85-90, 2013. 2146-460X 2146-4596 http://hdl.handle.net/11449/228288 10.3233/PGE-13052 2-s2.0-85013578705 |
url |
http://dx.doi.org/10.3233/PGE-13052 http://hdl.handle.net/11449/228288 |
identifier_str_mv |
Journal of Pediatric Genetics, v. 2, n. 2, p. 85-90, 2013. 2146-460X 2146-4596 10.3233/PGE-13052 2-s2.0-85013578705 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Pediatric Genetics |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
85-90 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803046109620207616 |