Perfil clínico e análise de sobrevida de pacientes com câncer de cabeça e pescoço não tabagistas e não etilistas

• Autor(a) principal: Mantovan, Bruna [UNESP]
• Data de Publicação: 2014
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/149546; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-01-27/000866320.pdf
• topic: Neoplasias de cabeça e pescoço; Neoplasias bucais; Neoplasias orofaríngeas; Fumo - Vício; Etiologia; Alcoolismo; Head and Neck Neoplasms

Alcohol use and smoking are considered the main risk factors for the head and neck cancer (HNC) development. However, some patients do not present an addiction history and still develop the disease. The goal of this study was to evaluate the clinic-pathological and survival profile of the non-smoking and non-drinking (NSND) HNC patients and compare them to patients with a history of chronic use of tobacco and alcohol. The clinical records of 667 patients with oral, oropharynx and larynx squamous cell carcinoma (SCC) treated at the Oral Oncology Center, Araçatuba Dental School (UNESP) were investigated. Epidemiological, clinical, pathological and treatment information were collected. The NSND patients accounted for 12.5% of overall sample of the HNC patients. Compared to smoking and drinking patients, NSND patients had a higher proportion of women, older people over 65 years and tumors localized mainly in oral region (86%) (p<0.05). Most of the tumors in NSND patients were diagnosed in advanced stages (III and IV) (65.8%). When compared to the smokers and/or drinkers, NSND population showed higher recurrence rate (p<0.05). There was no difference in overall survival rate after five years among NSND patients and smoking and drinking patients (p>0.05). We conclude that the NSND HCN patients have distinct clinic profile