SUFENTANIL INTRANASAL COME MEDICACAO PRE-ANESTESICA EM CRIANCAS

• Autor(a) principal: Ganem, E. N. [UNESP]
• Data de Publicação: 1995
• Outros Autores: Castiglia, Yara Marcondes Machado [UNESP], Do Nascimento, P. [UNESP], De Souza, M. F. [UNESP], Módolo, Norma Sueli Pinheiro [UNESP]
• Tipo de documento: Artigo
• Idioma: spa
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.sba.com.br/arquivos/revista/rba/set95295.pdf; http://hdl.handle.net/11449/64571
• topic: Pediatric anesthesia; Premedication, sufentanil intranasal; sufentanil; anxiety; child; clinical article; clinical trial; drug absorption; drug efficacy; elective surgery; human; intranasal drug administration; pediatric anesthesia; preoperative care; preschool child; school child

Background and objectives: Among the different routes used for the administration of preoperative medication, the intranasal route offers the advantage of a rapid systemic absorption as well as the avoidance of painful intramuscular and intravenous injections. The aim of the present study is to evaluate the efficacy of sufentanil as a preoperative medication for the reduction of anxiety in pediatric patients in addition to its effects on the children's behaviour during the induction of anesthesia. Methods - Thirty patients whose ages ranged from 1 to 9 years old, physical status ASA 1, submitted to elective surgeries participated in the study and received sufentanil (2 μg.kg-1) by the intranasal route as preoperative medication. Using the modified Doughty index, the anxiety level was evaluated at 3 moments: To upon arrival of the child with parents: T5 and T10, five and ten minutes after the administration of the drug respectively. Behaviour during the induction of anesthesia was also evaluated. Induction of anesthesia was performed thiopental or ketamine. Results - The level of anxiety was not lower ten minutes after the administration of sufentanil and no improvement in the quality of the anesthetic induction was observed. Conclusions - Intranasal sufentanil in the doses used in this study did not prove to be efficient in the reduction of the anxiety level nor did it improve the quality of the induction of anesthesia when the period between the drug administration and separation from the parents was only ten minutes.