Effects of an Er,Cr:YSGG Laser on Bone Regeneration in Critical-Sized Calvarial Defects of Rats Exposed to Inhalation of Cigarette Smoke

• Autor(a) principal: Pavone, Chaine
• Data de Publicação: 2019
• Outros Autores: Scardueli, Cássio Rocha [UNESP], De Oliveira, Guilherme José Pimentel Lopes, Cerri, Paulo Sérgio [UNESP], Marcantonio Junior, Elcio [UNESP], Marcantonio, Rosemary Adriana Chiérici [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1089/photob.2018.4546; http://hdl.handle.net/11449/189499
• topic: bone repair; Er Cr:YSGG laser; osteotomy; smoking

Objective: To evaluate the effect of the Er,Cr:YSGG laser on healing of critical-sized calvarial defects (CSDs) in rats submitted to inhalation of cigarette smoke. Background: Smoking has been implicated with the delay in the bone healing after osteotomy procedures, then the use of the Er,Cr:YSGG laser for osteotomy in smokers could be an alternative to the conventional drills. Methods: One hundred animals were randomly allocated into four groups: Trephine-The CSDs were made with a trephine drill in healthy rats; Er,Cr:YSGG-The CSDs were made with the Er,Cr:YSGG laser in healthy rats; Trephine-S-The CSDs were made with a trephine drill in rats exposed to cigarette smoke; and Er,Cr:YSGG-S-The CSDs were made with the Er,Cr:YSGG laser in rats exposed to cigarette smoke. The inhalation of cigarette smoke started 7 days before the surgical procedure until euthanasia (immediately, 7, 15, 30, or 60 days after the surgical procedure). A histometric analysis and a histological description were performed to evaluate (1) the residual linear lengths and bone formation in the CSDs; (2) the quality of bone healing. Results: The use of Er,Cr:YSGG laser induces more bone formation compared with the trephine in smokers; however, the closure of the CSD was only superior in the Er,Cr:YSGG-S group compared to the Trephine-S group at the 60-day period. Conclusions: The use of the Er,Cr:YSGG laser stimulated the bone repair process after osteotomy procedures in animals submitted to exposure of inhalation of cigarette smoke.