Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0102-86502013000500009 http://hdl.handle.net/11449/29026 |
Resumo: | PURPOSE: To analyze the clinicopathological features and outcome of patients with pathologically proven superficial squamous cell carcinoma of the esophagus. METHODS: A total of 234 consecutive cases of esophageal carcinoma in a 15-year period were reviewed. RESULTS: Superficial esophageal cancer was found in five patients (2.1%). They were four men and one woman and the mean age was 52.5 years. Smoking and alcohol were the main risk factors. Achalasia due to Chagas disease occurred in one patient and a second primary tumor developed in the larynx in another patient. Four patients underwent esophagectomy and one patient received chemoradiotherapy. The histopathologic diagnosis was of squamous cell carcinoma in all cases. Intramucosal tumor (Tis) was identified in three cases and superficially invasive carcinoma in two cases. Four patients are free of disease with survival times of two, four, six and nine years. The patient who developed laryngeal cancer died six years after esophagectomy. CONCLUSION: Long-term survival in patients with esophageal cancer is related to early diagnosis. Therefore, a less aggressive surgical approach, such as endoscopic resection, may be a good option for these patients, if depth of tumor invasion can be accurately predicted by the new imaging tools. |
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Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological studyCarcinomaSquamous CellEsophageal NeoplasmsEarly Detection of CancerPURPOSE: To analyze the clinicopathological features and outcome of patients with pathologically proven superficial squamous cell carcinoma of the esophagus. METHODS: A total of 234 consecutive cases of esophageal carcinoma in a 15-year period were reviewed. RESULTS: Superficial esophageal cancer was found in five patients (2.1%). They were four men and one woman and the mean age was 52.5 years. Smoking and alcohol were the main risk factors. Achalasia due to Chagas disease occurred in one patient and a second primary tumor developed in the larynx in another patient. Four patients underwent esophagectomy and one patient received chemoradiotherapy. The histopathologic diagnosis was of squamous cell carcinoma in all cases. Intramucosal tumor (Tis) was identified in three cases and superficially invasive carcinoma in two cases. Four patients are free of disease with survival times of two, four, six and nine years. The patient who developed laryngeal cancer died six years after esophagectomy. CONCLUSION: Long-term survival in patients with esophageal cancer is related to early diagnosis. Therefore, a less aggressive surgical approach, such as endoscopic resection, may be a good option for these patients, if depth of tumor invasion can be accurately predicted by the new imaging tools.UNESP Botucatu Medical School Department of SurgeryTriangulo Mineiro University Faculty of Medicine Department of Surgery, Gastroenterology Surgery DivisionUNESP Botucatu Medical School Investigative Pathology DivisionUNESP Botucatu Medical School Department of SurgeryUNESP Botucatu Medical School Investigative Pathology DivisionSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaUniversidade Estadual Paulista (Unesp)Triangulo Mineiro University Faculty of Medicine Department of Surgery, Gastroenterology Surgery DivisionHenry, Maria Aparecida Coelho de Arruda [UNESP]Lerco, Mauro Masson [UNESP]Naresse, Luiz Eduardo [UNESP]Crema, EduardoRodrigues, Maria Aparecida Marchesan [UNESP]2014-05-20T15:14:03Z2014-05-20T15:14:03Z2013-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article373-378application/pdfhttp://dx.doi.org/10.1590/S0102-86502013000500009Acta Cirúrgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 28, n. 5, p. 373-378, 2013.0102-8650http://hdl.handle.net/11449/2902610.1590/S0102-86502013000500009S0102-86502013000500009WOS:000319994200009S0102-86502013000500009.pdf37692555477382834728690596167767SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Cirúrgica Brasileira0.9330,395info:eu-repo/semantics/openAccess2023-11-01T06:10:40Zoai:repositorio.unesp.br:11449/29026Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-01T06:10:40Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study |
title |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study |
spellingShingle |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study Henry, Maria Aparecida Coelho de Arruda [UNESP] Carcinoma Squamous Cell Esophageal Neoplasms Early Detection of Cancer |
title_short |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study |
title_full |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study |
title_fullStr |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study |
title_full_unstemmed |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study |
title_sort |
Outcome of superficial squamous cell carcinoma of the esophagus: a clinicopathological study |
author |
Henry, Maria Aparecida Coelho de Arruda [UNESP] |
author_facet |
Henry, Maria Aparecida Coelho de Arruda [UNESP] Lerco, Mauro Masson [UNESP] Naresse, Luiz Eduardo [UNESP] Crema, Eduardo Rodrigues, Maria Aparecida Marchesan [UNESP] |
author_role |
author |
author2 |
Lerco, Mauro Masson [UNESP] Naresse, Luiz Eduardo [UNESP] Crema, Eduardo Rodrigues, Maria Aparecida Marchesan [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Triangulo Mineiro University Faculty of Medicine Department of Surgery, Gastroenterology Surgery Division |
dc.contributor.author.fl_str_mv |
Henry, Maria Aparecida Coelho de Arruda [UNESP] Lerco, Mauro Masson [UNESP] Naresse, Luiz Eduardo [UNESP] Crema, Eduardo Rodrigues, Maria Aparecida Marchesan [UNESP] |
dc.subject.por.fl_str_mv |
Carcinoma Squamous Cell Esophageal Neoplasms Early Detection of Cancer |
topic |
Carcinoma Squamous Cell Esophageal Neoplasms Early Detection of Cancer |
description |
PURPOSE: To analyze the clinicopathological features and outcome of patients with pathologically proven superficial squamous cell carcinoma of the esophagus. METHODS: A total of 234 consecutive cases of esophageal carcinoma in a 15-year period were reviewed. RESULTS: Superficial esophageal cancer was found in five patients (2.1%). They were four men and one woman and the mean age was 52.5 years. Smoking and alcohol were the main risk factors. Achalasia due to Chagas disease occurred in one patient and a second primary tumor developed in the larynx in another patient. Four patients underwent esophagectomy and one patient received chemoradiotherapy. The histopathologic diagnosis was of squamous cell carcinoma in all cases. Intramucosal tumor (Tis) was identified in three cases and superficially invasive carcinoma in two cases. Four patients are free of disease with survival times of two, four, six and nine years. The patient who developed laryngeal cancer died six years after esophagectomy. CONCLUSION: Long-term survival in patients with esophageal cancer is related to early diagnosis. Therefore, a less aggressive surgical approach, such as endoscopic resection, may be a good option for these patients, if depth of tumor invasion can be accurately predicted by the new imaging tools. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-05-01 2014-05-20T15:14:03Z 2014-05-20T15:14:03Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0102-86502013000500009 Acta Cirúrgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 28, n. 5, p. 373-378, 2013. 0102-8650 http://hdl.handle.net/11449/29026 10.1590/S0102-86502013000500009 S0102-86502013000500009 WOS:000319994200009 S0102-86502013000500009.pdf 3769255547738283 4728690596167767 |
url |
http://dx.doi.org/10.1590/S0102-86502013000500009 http://hdl.handle.net/11449/29026 |
identifier_str_mv |
Acta Cirúrgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 28, n. 5, p. 373-378, 2013. 0102-8650 10.1590/S0102-86502013000500009 S0102-86502013000500009 WOS:000319994200009 S0102-86502013000500009.pdf 3769255547738283 4728690596167767 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Acta Cirúrgica Brasileira 0.933 0,395 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
373-378 application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1803046266265927680 |