Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados

Detalhes bibliográficos
Autor(a) principal: Daiuto, Érica Regina [UNESP]
Data de Publicação: 2006
Outros Autores: Cereda, M. P. [UNESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360
http://hdl.handle.net/11449/69329
Resumo: Starches and modified starch derivations are used as carriers in the spray drying processing where apparent density is an important characteristic and should be controlled in dehydrated products for pharmaceutical use. In Brazil, the commercial starches are made from corn and cassava, but there are others with potential for extraction. The canna and taro starches were selected because they represent the extremes of granule size and thus allow the effect of this size on the apparent density of spray dried products to be tested. For comparison, commercial cassava and corn starches which are used in spray-drying and have granules of intermediate size, were also tested. The spray-drying process was carried out with a LabPlant SD 04 Spray Dryer, operating at a pressure of 6 lb/in2, air of 7,6 mL/minute, and 1 cm atomizing nozzle. The air inlet temperature was set at 200°C this model does not allow regulating outlet temperature. The spray-dryer products had boldo leaf extract as base, using the four starches as carrier. The dry product was evaluated for humidity, water activity (Aw), granulometry and apparent density. The results showed that the size of the particles, which was a consequence of the size of the starch granules, influenced the apparent density of the spray dried products, which as higher (694, 27 g/mL) for the canna starch and lower (456, 13 g/mL) for taro starch. Corn and cassava starches showed very close and intermediate values, 521,51 and 58,48 g/mL, which also represent the standard range of starch granule size.
id UNSP_401cb74b5672d0392f06cace8324e2d6
oai_identifier_str oai:repositorio.unesp.br:11449/69329
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizadosThe influence of starch granules granulometry on apparent density of spray-dried productApparent densityGranulometrySpray-dryerStarchesdrug carrierstarchair temperatureBrazilcassavacorncorrelation analysisdensityextractionhumiditynebulizationparticle sizeplant leafspray dryingStarches and modified starch derivations are used as carriers in the spray drying processing where apparent density is an important characteristic and should be controlled in dehydrated products for pharmaceutical use. In Brazil, the commercial starches are made from corn and cassava, but there are others with potential for extraction. The canna and taro starches were selected because they represent the extremes of granule size and thus allow the effect of this size on the apparent density of spray dried products to be tested. For comparison, commercial cassava and corn starches which are used in spray-drying and have granules of intermediate size, were also tested. The spray-drying process was carried out with a LabPlant SD 04 Spray Dryer, operating at a pressure of 6 lb/in2, air of 7,6 mL/minute, and 1 cm atomizing nozzle. The air inlet temperature was set at 200°C this model does not allow regulating outlet temperature. The spray-dryer products had boldo leaf extract as base, using the four starches as carrier. The dry product was evaluated for humidity, water activity (Aw), granulometry and apparent density. The results showed that the size of the particles, which was a consequence of the size of the starch granules, influenced the apparent density of the spray dried products, which as higher (694, 27 g/mL) for the canna starch and lower (456, 13 g/mL) for taro starch. Corn and cassava starches showed very close and intermediate values, 521,51 and 58,48 g/mL, which also represent the standard range of starch granule size.Amidos e seus derivados são utilizados como carregadores em processos de secagem de produtos por atomização onde a densidade aparente é característica importante e deve ser controlada nos produtos desidratados de uso farmacêutico. No Brasil os amidos comerciais são originários de milho e mandioca, mas existem outros com potencial para extração. Os amidos de biri e taro foram selecionados por representarem extremos de tamanho de grânulos e assim verificar o efeito do tamanho sobre a densidade aparente de produtos desidratados por atomização. Foram usados para comparação os amidos comerciais de mandioca e milho, por serem de uso comum em produtos atomizados e apresentarem tamanhos intermediários de grânulos. A atomização foi feita em Spray Dryer Lab Plant SD 04, operando sob pressão de 6 lb/in2, fluxo 7,6 mL/mim, e bico 1 cm. A temperatura de entrada foi fixada em 200ºC mas este modelo de equipamento não permite regular a temperatura de saída. Os produtos atomizados tiveram extrato de boldo como base, usando os quatro amidos como suporte. O produto seco foi avaliado quanto à umidade, atividade de água, tamanho das partículas e densidade aparente. Os resultados mostraram que o tamanho das partículas, e por decorrência do tamanho dos grânulos de amido, têm influência sobre a densidade aparente do produto final, que foi maior (694, 27 g/mL) para o amido de biri e menor (456,13 g/mL) para amido de taro. Os amidos de milho e mandioca proporcionaram valores muito próximos e intermediários, de 521, 51 e 581, 48 g/mL, que representam também o padrão de variação de tamanho dos grânulos. Palavras-chave: atomização; densidade aparente; granulometria; amidos.Departamento de Gestão e Tecnologia Agroindustrial Faculdade de Ciências Agronômicas Universidade Estadual Paulista, UNESP, Botucatu, SPDepartamento de Gestão e Tecnologia Agroindustrial Faculdade de Ciências Agronômicas Fazenda Experimental Lageado, R. Jose Barbosa de Barros, 1780, CEP: 18610-307 - Botucatu - SPDepartamento de Gestão e Tecnologia Agroindustrial Faculdade de Ciências Agronômicas Universidade Estadual Paulista, UNESP, Botucatu, SPUniversidade Estadual Paulista (Unesp)Daiuto, Érica Regina [UNESP]Cereda, M. P. [UNESP]2014-05-27T11:22:05Z2014-05-27T11:22:05Z2006-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article51-56application/pdfhttp://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 27, n. 1, p. 51-56, 2006.1808-4532http://hdl.handle.net/11449/693292-s2.0-340471775152-s2.0-34047177515.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporRevista de Ciências Farmacêuticas Básica e Aplicada0,131info:eu-repo/semantics/openAccess2023-10-14T06:04:33Zoai:repositorio.unesp.br:11449/69329Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-14T06:04:33Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
The influence of starch granules granulometry on apparent density of spray-dried product
title Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
spellingShingle Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
Daiuto, Érica Regina [UNESP]
Apparent density
Granulometry
Spray-dryer
Starches
drug carrier
starch
air temperature
Brazil
cassava
corn
correlation analysis
density
extraction
humidity
nebulization
particle size
plant leaf
spray drying
title_short Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
title_full Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
title_fullStr Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
title_full_unstemmed Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
title_sort Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
author Daiuto, Érica Regina [UNESP]
author_facet Daiuto, Érica Regina [UNESP]
Cereda, M. P. [UNESP]
author_role author
author2 Cereda, M. P. [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Daiuto, Érica Regina [UNESP]
Cereda, M. P. [UNESP]
dc.subject.por.fl_str_mv Apparent density
Granulometry
Spray-dryer
Starches
drug carrier
starch
air temperature
Brazil
cassava
corn
correlation analysis
density
extraction
humidity
nebulization
particle size
plant leaf
spray drying
topic Apparent density
Granulometry
Spray-dryer
Starches
drug carrier
starch
air temperature
Brazil
cassava
corn
correlation analysis
density
extraction
humidity
nebulization
particle size
plant leaf
spray drying
description Starches and modified starch derivations are used as carriers in the spray drying processing where apparent density is an important characteristic and should be controlled in dehydrated products for pharmaceutical use. In Brazil, the commercial starches are made from corn and cassava, but there are others with potential for extraction. The canna and taro starches were selected because they represent the extremes of granule size and thus allow the effect of this size on the apparent density of spray dried products to be tested. For comparison, commercial cassava and corn starches which are used in spray-drying and have granules of intermediate size, were also tested. The spray-drying process was carried out with a LabPlant SD 04 Spray Dryer, operating at a pressure of 6 lb/in2, air of 7,6 mL/minute, and 1 cm atomizing nozzle. The air inlet temperature was set at 200°C this model does not allow regulating outlet temperature. The spray-dryer products had boldo leaf extract as base, using the four starches as carrier. The dry product was evaluated for humidity, water activity (Aw), granulometry and apparent density. The results showed that the size of the particles, which was a consequence of the size of the starch granules, influenced the apparent density of the spray dried products, which as higher (694, 27 g/mL) for the canna starch and lower (456, 13 g/mL) for taro starch. Corn and cassava starches showed very close and intermediate values, 521,51 and 58,48 g/mL, which also represent the standard range of starch granule size.
publishDate 2006
dc.date.none.fl_str_mv 2006-12-01
2014-05-27T11:22:05Z
2014-05-27T11:22:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360
Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 27, n. 1, p. 51-56, 2006.
1808-4532
http://hdl.handle.net/11449/69329
2-s2.0-34047177515
2-s2.0-34047177515.pdf
url http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360
http://hdl.handle.net/11449/69329
identifier_str_mv Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 27, n. 1, p. 51-56, 2006.
1808-4532
2-s2.0-34047177515
2-s2.0-34047177515.pdf
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista de Ciências Farmacêuticas Básica e Aplicada
0,131
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 51-56
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1797789390287667200