Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados
Autor(a) principal: | |
---|---|
Data de Publicação: | 2006 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360 http://hdl.handle.net/11449/69329 |
Resumo: | Starches and modified starch derivations are used as carriers in the spray drying processing where apparent density is an important characteristic and should be controlled in dehydrated products for pharmaceutical use. In Brazil, the commercial starches are made from corn and cassava, but there are others with potential for extraction. The canna and taro starches were selected because they represent the extremes of granule size and thus allow the effect of this size on the apparent density of spray dried products to be tested. For comparison, commercial cassava and corn starches which are used in spray-drying and have granules of intermediate size, were also tested. The spray-drying process was carried out with a LabPlant SD 04 Spray Dryer, operating at a pressure of 6 lb/in2, air of 7,6 mL/minute, and 1 cm atomizing nozzle. The air inlet temperature was set at 200°C this model does not allow regulating outlet temperature. The spray-dryer products had boldo leaf extract as base, using the four starches as carrier. The dry product was evaluated for humidity, water activity (Aw), granulometry and apparent density. The results showed that the size of the particles, which was a consequence of the size of the starch granules, influenced the apparent density of the spray dried products, which as higher (694, 27 g/mL) for the canna starch and lower (456, 13 g/mL) for taro starch. Corn and cassava starches showed very close and intermediate values, 521,51 and 58,48 g/mL, which also represent the standard range of starch granule size. |
id |
UNSP_401cb74b5672d0392f06cace8324e2d6 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/69329 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizadosThe influence of starch granules granulometry on apparent density of spray-dried productApparent densityGranulometrySpray-dryerStarchesdrug carrierstarchair temperatureBrazilcassavacorncorrelation analysisdensityextractionhumiditynebulizationparticle sizeplant leafspray dryingStarches and modified starch derivations are used as carriers in the spray drying processing where apparent density is an important characteristic and should be controlled in dehydrated products for pharmaceutical use. In Brazil, the commercial starches are made from corn and cassava, but there are others with potential for extraction. The canna and taro starches were selected because they represent the extremes of granule size and thus allow the effect of this size on the apparent density of spray dried products to be tested. For comparison, commercial cassava and corn starches which are used in spray-drying and have granules of intermediate size, were also tested. The spray-drying process was carried out with a LabPlant SD 04 Spray Dryer, operating at a pressure of 6 lb/in2, air of 7,6 mL/minute, and 1 cm atomizing nozzle. The air inlet temperature was set at 200°C this model does not allow regulating outlet temperature. The spray-dryer products had boldo leaf extract as base, using the four starches as carrier. The dry product was evaluated for humidity, water activity (Aw), granulometry and apparent density. The results showed that the size of the particles, which was a consequence of the size of the starch granules, influenced the apparent density of the spray dried products, which as higher (694, 27 g/mL) for the canna starch and lower (456, 13 g/mL) for taro starch. Corn and cassava starches showed very close and intermediate values, 521,51 and 58,48 g/mL, which also represent the standard range of starch granule size.Amidos e seus derivados são utilizados como carregadores em processos de secagem de produtos por atomização onde a densidade aparente é característica importante e deve ser controlada nos produtos desidratados de uso farmacêutico. No Brasil os amidos comerciais são originários de milho e mandioca, mas existem outros com potencial para extração. Os amidos de biri e taro foram selecionados por representarem extremos de tamanho de grânulos e assim verificar o efeito do tamanho sobre a densidade aparente de produtos desidratados por atomização. Foram usados para comparação os amidos comerciais de mandioca e milho, por serem de uso comum em produtos atomizados e apresentarem tamanhos intermediários de grânulos. A atomização foi feita em Spray Dryer Lab Plant SD 04, operando sob pressão de 6 lb/in2, fluxo 7,6 mL/mim, e bico 1 cm. A temperatura de entrada foi fixada em 200ºC mas este modelo de equipamento não permite regular a temperatura de saída. Os produtos atomizados tiveram extrato de boldo como base, usando os quatro amidos como suporte. O produto seco foi avaliado quanto à umidade, atividade de água, tamanho das partículas e densidade aparente. Os resultados mostraram que o tamanho das partículas, e por decorrência do tamanho dos grânulos de amido, têm influência sobre a densidade aparente do produto final, que foi maior (694, 27 g/mL) para o amido de biri e menor (456,13 g/mL) para amido de taro. Os amidos de milho e mandioca proporcionaram valores muito próximos e intermediários, de 521, 51 e 581, 48 g/mL, que representam também o padrão de variação de tamanho dos grânulos. Palavras-chave: atomização; densidade aparente; granulometria; amidos.Departamento de Gestão e Tecnologia Agroindustrial Faculdade de Ciências Agronômicas Universidade Estadual Paulista, UNESP, Botucatu, SPDepartamento de Gestão e Tecnologia Agroindustrial Faculdade de Ciências Agronômicas Fazenda Experimental Lageado, R. Jose Barbosa de Barros, 1780, CEP: 18610-307 - Botucatu - SPDepartamento de Gestão e Tecnologia Agroindustrial Faculdade de Ciências Agronômicas Universidade Estadual Paulista, UNESP, Botucatu, SPUniversidade Estadual Paulista (Unesp)Daiuto, Érica Regina [UNESP]Cereda, M. P. [UNESP]2014-05-27T11:22:05Z2014-05-27T11:22:05Z2006-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article51-56application/pdfhttp://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 27, n. 1, p. 51-56, 2006.1808-4532http://hdl.handle.net/11449/693292-s2.0-340471775152-s2.0-34047177515.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporRevista de Ciências Farmacêuticas Básica e Aplicada0,131info:eu-repo/semantics/openAccess2023-10-14T06:04:33Zoai:repositorio.unesp.br:11449/69329Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-14T06:04:33Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados The influence of starch granules granulometry on apparent density of spray-dried product |
title |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados |
spellingShingle |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados Daiuto, Érica Regina [UNESP] Apparent density Granulometry Spray-dryer Starches drug carrier starch air temperature Brazil cassava corn correlation analysis density extraction humidity nebulization particle size plant leaf spray drying |
title_short |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados |
title_full |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados |
title_fullStr |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados |
title_full_unstemmed |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados |
title_sort |
Influência da granulometria de grânulos de amido sobre a densidade aparente de extratos atomizados |
author |
Daiuto, Érica Regina [UNESP] |
author_facet |
Daiuto, Érica Regina [UNESP] Cereda, M. P. [UNESP] |
author_role |
author |
author2 |
Cereda, M. P. [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Daiuto, Érica Regina [UNESP] Cereda, M. P. [UNESP] |
dc.subject.por.fl_str_mv |
Apparent density Granulometry Spray-dryer Starches drug carrier starch air temperature Brazil cassava corn correlation analysis density extraction humidity nebulization particle size plant leaf spray drying |
topic |
Apparent density Granulometry Spray-dryer Starches drug carrier starch air temperature Brazil cassava corn correlation analysis density extraction humidity nebulization particle size plant leaf spray drying |
description |
Starches and modified starch derivations are used as carriers in the spray drying processing where apparent density is an important characteristic and should be controlled in dehydrated products for pharmaceutical use. In Brazil, the commercial starches are made from corn and cassava, but there are others with potential for extraction. The canna and taro starches were selected because they represent the extremes of granule size and thus allow the effect of this size on the apparent density of spray dried products to be tested. For comparison, commercial cassava and corn starches which are used in spray-drying and have granules of intermediate size, were also tested. The spray-drying process was carried out with a LabPlant SD 04 Spray Dryer, operating at a pressure of 6 lb/in2, air of 7,6 mL/minute, and 1 cm atomizing nozzle. The air inlet temperature was set at 200°C this model does not allow regulating outlet temperature. The spray-dryer products had boldo leaf extract as base, using the four starches as carrier. The dry product was evaluated for humidity, water activity (Aw), granulometry and apparent density. The results showed that the size of the particles, which was a consequence of the size of the starch granules, influenced the apparent density of the spray dried products, which as higher (694, 27 g/mL) for the canna starch and lower (456, 13 g/mL) for taro starch. Corn and cassava starches showed very close and intermediate values, 521,51 and 58,48 g/mL, which also represent the standard range of starch granule size. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-12-01 2014-05-27T11:22:05Z 2014-05-27T11:22:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360 Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 27, n. 1, p. 51-56, 2006. 1808-4532 http://hdl.handle.net/11449/69329 2-s2.0-34047177515 2-s2.0-34047177515.pdf |
url |
http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/360 http://hdl.handle.net/11449/69329 |
identifier_str_mv |
Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 27, n. 1, p. 51-56, 2006. 1808-4532 2-s2.0-34047177515 2-s2.0-34047177515.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista de Ciências Farmacêuticas Básica e Aplicada 0,131 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
51-56 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797789390287667200 |