Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis

Detalhes bibliográficos
Autor(a) principal: Cornara, L.
Data de Publicação: 2018
Outros Autores: Fortuna-Perez, A. P. [UNESP], Bruni, I., Salis, A., Damonte, G., Borghesi, B., Clericuzio, M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/s00414-018-1774-z
http://hdl.handle.net/11449/164509
Resumo: Dried herbal preparations, based on Zornia latifolia, are commonly sold on web, mainly for their supposed hallucinogenic properties. In this work, we demonstrate that these commercial products contain a different Fabacea, i.e., Stylosanthes guianensis, a cheaper plant, widely cultivated in tropical regions as a fodder legume. We were provided with plant samples of true Zornia latifolia from Brazil, and carried out a thorough comparison of the two species. The assignment of commercial samples was performed by means of micro-morphological analysis, DNA barcoding, and partial phytochemical investigation. We observed that Z. latifolia contains large amounts of flavonoid di-glycosides derived from luteolin, apigenin, and genistein, while in S. guianensis lesser amounts of flavonoids, mainly derived from quercetin, were found. It is likely that the spasmolytic and anxiolytic properties of Z. latifolia, as reported in traditional medicine, derive from its contents in apigenin and/or genistein.
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spelling Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensisSmart drugsMorphologic analysisDNA barcodingLuteolinApigeninGenisteinDried herbal preparations, based on Zornia latifolia, are commonly sold on web, mainly for their supposed hallucinogenic properties. In this work, we demonstrate that these commercial products contain a different Fabacea, i.e., Stylosanthes guianensis, a cheaper plant, widely cultivated in tropical regions as a fodder legume. We were provided with plant samples of true Zornia latifolia from Brazil, and carried out a thorough comparison of the two species. The assignment of commercial samples was performed by means of micro-morphological analysis, DNA barcoding, and partial phytochemical investigation. We observed that Z. latifolia contains large amounts of flavonoid di-glycosides derived from luteolin, apigenin, and genistein, while in S. guianensis lesser amounts of flavonoids, mainly derived from quercetin, were found. It is likely that the spasmolytic and anxiolytic properties of Z. latifolia, as reported in traditional medicine, derive from its contents in apigenin and/or genistein.Univ Genoa, Dipartimento DISTAV, Corso Europa 26, I-16132 Genoa, ItalyUniv Estadual Paulista, Dept Bot, Botucatu, SP, BrazilUniv Milano Bicocca, Dipartimento Biotecnol & Biosci, I-20126 Milan, ItalyUniv Genoa, CEBR, Viale Benedetto 15 5, I-16132 Genoa, ItalyUniv Piemonte Orientale, Dipartimento Sci & Innovaz Tecnol, Viale T Michel 11, I-15121 Alessandria, ItalyUniv Estadual Paulista, Dept Bot, Botucatu, SP, BrazilSpringerUniv GenoaUniversidade Estadual Paulista (Unesp)Univ Milano BicoccaUniv Piemonte OrientaleCornara, L.Fortuna-Perez, A. P. [UNESP]Bruni, I.Salis, A.Damonte, G.Borghesi, B.Clericuzio, M.2018-11-26T17:54:50Z2018-11-26T17:54:50Z2018-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1321-1331application/pdfhttp://dx.doi.org/10.1007/s00414-018-1774-zInternational Journal Of Legal Medicine. New York: Springer, v. 132, n. 5, p. 1321-1331, 2018.0937-9827http://hdl.handle.net/11449/16450910.1007/s00414-018-1774-zWOS:000441286500013WOS000441286500013.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal Of Legal Medicine1,210info:eu-repo/semantics/openAccess2023-10-30T06:06:22Zoai:repositorio.unesp.br:11449/164509Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:25:18.959729Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
title Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
spellingShingle Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
Cornara, L.
Smart drugs
Morphologic analysis
DNA barcoding
Luteolin
Apigenin
Genistein
title_short Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
title_full Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
title_fullStr Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
title_full_unstemmed Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
title_sort Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis
author Cornara, L.
author_facet Cornara, L.
Fortuna-Perez, A. P. [UNESP]
Bruni, I.
Salis, A.
Damonte, G.
Borghesi, B.
Clericuzio, M.
author_role author
author2 Fortuna-Perez, A. P. [UNESP]
Bruni, I.
Salis, A.
Damonte, G.
Borghesi, B.
Clericuzio, M.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Univ Genoa
Universidade Estadual Paulista (Unesp)
Univ Milano Bicocca
Univ Piemonte Orientale
dc.contributor.author.fl_str_mv Cornara, L.
Fortuna-Perez, A. P. [UNESP]
Bruni, I.
Salis, A.
Damonte, G.
Borghesi, B.
Clericuzio, M.
dc.subject.por.fl_str_mv Smart drugs
Morphologic analysis
DNA barcoding
Luteolin
Apigenin
Genistein
topic Smart drugs
Morphologic analysis
DNA barcoding
Luteolin
Apigenin
Genistein
description Dried herbal preparations, based on Zornia latifolia, are commonly sold on web, mainly for their supposed hallucinogenic properties. In this work, we demonstrate that these commercial products contain a different Fabacea, i.e., Stylosanthes guianensis, a cheaper plant, widely cultivated in tropical regions as a fodder legume. We were provided with plant samples of true Zornia latifolia from Brazil, and carried out a thorough comparison of the two species. The assignment of commercial samples was performed by means of micro-morphological analysis, DNA barcoding, and partial phytochemical investigation. We observed that Z. latifolia contains large amounts of flavonoid di-glycosides derived from luteolin, apigenin, and genistein, while in S. guianensis lesser amounts of flavonoids, mainly derived from quercetin, were found. It is likely that the spasmolytic and anxiolytic properties of Z. latifolia, as reported in traditional medicine, derive from its contents in apigenin and/or genistein.
publishDate 2018
dc.date.none.fl_str_mv 2018-11-26T17:54:50Z
2018-11-26T17:54:50Z
2018-09-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/s00414-018-1774-z
International Journal Of Legal Medicine. New York: Springer, v. 132, n. 5, p. 1321-1331, 2018.
0937-9827
http://hdl.handle.net/11449/164509
10.1007/s00414-018-1774-z
WOS:000441286500013
WOS000441286500013.pdf
url http://dx.doi.org/10.1007/s00414-018-1774-z
http://hdl.handle.net/11449/164509
identifier_str_mv International Journal Of Legal Medicine. New York: Springer, v. 132, n. 5, p. 1321-1331, 2018.
0937-9827
10.1007/s00414-018-1774-z
WOS:000441286500013
WOS000441286500013.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal Of Legal Medicine
1,210
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1321-1331
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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