Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s00244-016-0281-9 http://hdl.handle.net/11449/161702 |
Resumo: | This study evaluated the alteration of the enzymatic system of the freshwater Asian clam exposed to different copper concentrations. Individuals of Corbicula fluminea were exposed to different concentrations of dissolved Cu (0.5, 1, and 2 mg L-1) for 7 days, then, biomarkers of oxidative stress (GST, GPx, GR), exposure (MTs), effect (AChE), and damage (LPO, DNA strand breaks) were quantified. Results showed positive correlations between dissolved metal concentrations and GPx, MTs, and DNA damage, and negative correlation with GST and AChE. In contrast, no clear trend was found for GR and LPO. In general, the established mechanisms of protection might have a beneficial effect on the decreasing ROS attack on membrane and the activation of the metallothioneins. Integrated biomarker analysis revealed that the measured alterations are well correlated with the levels of increasing dissolved copper concentrations in water, demonstrating the effectiveness of this organism for biomonitoring approach purposes. |
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Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity TestsThis study evaluated the alteration of the enzymatic system of the freshwater Asian clam exposed to different copper concentrations. Individuals of Corbicula fluminea were exposed to different concentrations of dissolved Cu (0.5, 1, and 2 mg L-1) for 7 days, then, biomarkers of oxidative stress (GST, GPx, GR), exposure (MTs), effect (AChE), and damage (LPO, DNA strand breaks) were quantified. Results showed positive correlations between dissolved metal concentrations and GPx, MTs, and DNA damage, and negative correlation with GST and AChE. In contrast, no clear trend was found for GR and LPO. In general, the established mechanisms of protection might have a beneficial effect on the decreasing ROS attack on membrane and the activation of the metallothioneins. Integrated biomarker analysis revealed that the measured alterations are well correlated with the levels of increasing dissolved copper concentrations in water, demonstrating the effectiveness of this organism for biomonitoring approach purposes.Bank Santander/UNESCO Chair UNITWIN/WiCopErasmus Mundus Programme for the MACOMA DoctoralConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Brazilian Aquatic Research Foundation (FUNDESPA)Univ Cadiz, UNESCO UNITWIN WiCop, Dept Phys Chem, Fac Marine & Environm Sci, Campus Rio San Pedro, Cadiz 11510, SpainUniv Estadual Paulista, Nucleo Estudos Poluicao & Ecotoxicol Aquat, Campus Expt Litoral Paulista, BR-11330900 Sao Vicente, SP, BrazilUniv Estadual Paulista, Nucleo Estudos Poluicao & Ecotoxicol Aquat, Campus Expt Litoral Paulista, BR-11330900 Sao Vicente, SP, BrazilErasmus Mundus Programme for the MACOMA Doctoral: SGA 2012-1701/001-001-EMJDCNPq: 479899/2013-4FAPESP: 2009/52762-6FAPESP: 2013/15482-0CNPq: 308649/2011-7CNPq: 311609/2014-7SpringerUniv CadizUniversidade Estadual Paulista (Unesp)Bonnail, EstefaniaBuruaem, Lucas M. [UNESP]Araujo, Giuliana S. [UNESP]Abessa, Denis M. S. [UNESP]Angel DelValls, T.2018-11-26T16:48:18Z2018-11-26T16:48:18Z2016-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article278-285application/pdfhttp://dx.doi.org/10.1007/s00244-016-0281-9Archives Of Environmental Contamination And Toxicology. New York: Springer, v. 71, n. 2, p. 278-285, 2016.0090-4341http://hdl.handle.net/11449/16170210.1007/s00244-016-0281-9WOS:000379340700012WOS000379340700012.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArchives Of Environmental Contamination And Toxicology0,773info:eu-repo/semantics/openAccess2023-12-14T06:18:21Zoai:repositorio.unesp.br:11449/161702Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-14T06:18:21Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests |
title |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests |
spellingShingle |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests Bonnail, Estefania |
title_short |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests |
title_full |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests |
title_fullStr |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests |
title_full_unstemmed |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests |
title_sort |
Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests |
author |
Bonnail, Estefania |
author_facet |
Bonnail, Estefania Buruaem, Lucas M. [UNESP] Araujo, Giuliana S. [UNESP] Abessa, Denis M. S. [UNESP] Angel DelValls, T. |
author_role |
author |
author2 |
Buruaem, Lucas M. [UNESP] Araujo, Giuliana S. [UNESP] Abessa, Denis M. S. [UNESP] Angel DelValls, T. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Univ Cadiz Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Bonnail, Estefania Buruaem, Lucas M. [UNESP] Araujo, Giuliana S. [UNESP] Abessa, Denis M. S. [UNESP] Angel DelValls, T. |
description |
This study evaluated the alteration of the enzymatic system of the freshwater Asian clam exposed to different copper concentrations. Individuals of Corbicula fluminea were exposed to different concentrations of dissolved Cu (0.5, 1, and 2 mg L-1) for 7 days, then, biomarkers of oxidative stress (GST, GPx, GR), exposure (MTs), effect (AChE), and damage (LPO, DNA strand breaks) were quantified. Results showed positive correlations between dissolved metal concentrations and GPx, MTs, and DNA damage, and negative correlation with GST and AChE. In contrast, no clear trend was found for GR and LPO. In general, the established mechanisms of protection might have a beneficial effect on the decreasing ROS attack on membrane and the activation of the metallothioneins. Integrated biomarker analysis revealed that the measured alterations are well correlated with the levels of increasing dissolved copper concentrations in water, demonstrating the effectiveness of this organism for biomonitoring approach purposes. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-08-01 2018-11-26T16:48:18Z 2018-11-26T16:48:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s00244-016-0281-9 Archives Of Environmental Contamination And Toxicology. New York: Springer, v. 71, n. 2, p. 278-285, 2016. 0090-4341 http://hdl.handle.net/11449/161702 10.1007/s00244-016-0281-9 WOS:000379340700012 WOS000379340700012.pdf |
url |
http://dx.doi.org/10.1007/s00244-016-0281-9 http://hdl.handle.net/11449/161702 |
identifier_str_mv |
Archives Of Environmental Contamination And Toxicology. New York: Springer, v. 71, n. 2, p. 278-285, 2016. 0090-4341 10.1007/s00244-016-0281-9 WOS:000379340700012 WOS000379340700012.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Archives Of Environmental Contamination And Toxicology 0,773 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
278-285 application/pdf |
dc.publisher.none.fl_str_mv |
Springer |
publisher.none.fl_str_mv |
Springer |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965278575001600 |