Efeito da infecção pulpar e periodontal na glicemia de ratos Wistar

• Autor(a) principal: Pereira, Thamiris Tieni [UNESP]
• Data de Publicação: 2012
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/149465; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-01-27/000855844.pdf
• topic: Diabetes mellitus; Doenças periodontais; Ratos Wistar

The objective of this work was to evaluate the interrelationship between pulp and/or periodontal diseases and diabetes systemic disease by glycemic monitoring. 80 mice of the Wistar family were used and divided into 8 groups of 10 animals: G1 - healthy mice; G2 - Pulp disease affected mice; G3 - periodontal disease affected mice; G4 - pulp and periodontal diseases affected mice; G5 - diabetic mice; G6 - diabetes and pulp disease affected mice; G7 - diabetes and pulp disease affected mice; G8 - diabetes, pulp and periodontal diseases affected mice. The diabetes was induced by applying streptozotocin, the pulp infection by the dental pulp exposure to oral environment and the periodontal disease by the manufacturing of obstruction of the dental cervix. The animals were assessed via glycemic monitoring throughout the experimental period and sacrificed after 30 dias. Was possible notice that in all groups of mice nondiabetic glucose curves were similar. However, any local diseases association was enough to raise the glucose levels of diabetic animals even higher. It was concluded that pulp disease alone not influences on blood glucose in diabetic mice, but periodontal disease alone or disease associated with the pulp influences glucose levels in diabetic mice