Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/134207 http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/28-01-2016/000857959.pdf |
Resumo: | Introduction: The use of biomaterials in reconstructions for dental implants has been widely discussed in recent years. Proposition: The aim of this work was to analize the biological behavior of the bioactive glass (Biogran®) and bovine bone (Endobon®) during the osseointegration process associated with implants with peri-implant defects in rat tibia. Material and Methods: 75 implants were installed in the left tibia of 75 male Wistar rats. The implants were divided into three experimental groups. In Group 1 (Control) was caused monocortical circular peri-implant defect and the implants were inserted and left only with clot. In Group 2 implants were inserted with the same bone defect and the space filled with Biogran® and in Group 3 the space between bone and implant was filled with Endobon®. The animals were euthanized at 14 and 42 days and there were the histological analysis, histometric (percentage of linear extension bone-implant contact - BIC and bone area - BA), immunohistochemistry (expression of the proteins osteocalcin - OC and osteopontin - OPN) and biomechanics (reverse torque). Results: Histologically all implants were osseointegrated. No statistically significant differences were observed in the values of reverse torque (p> 0.05) at 42 days. For BIC, at 14 days was 8.29; 15.04; and 16.20% for the groups 1, 2 and 3, respectively. After 42 days, the BIC values were 30.84; 33.13; and 13.93% for the same groups, demonstrating that there were no statistical differences between groups, but with different responses between periods. For the quantification of bone formation per area (BA), the response differs between groups. The average BA response in Group 1 (18.75%) did not differ from the average Group 3 response (21.62%). However, different from Group 2 (34.73%). The immunohistochemical results were analyzed by Qualitative... |
id |
UNSP_428421fda32e114194b3f66f009f6a20 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/134207 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantaresImplantes dentáriosTransplante ósseoMateriais biomédicosDental implantsIntroduction: The use of biomaterials in reconstructions for dental implants has been widely discussed in recent years. Proposition: The aim of this work was to analize the biological behavior of the bioactive glass (Biogran®) and bovine bone (Endobon®) during the osseointegration process associated with implants with peri-implant defects in rat tibia. Material and Methods: 75 implants were installed in the left tibia of 75 male Wistar rats. The implants were divided into three experimental groups. In Group 1 (Control) was caused monocortical circular peri-implant defect and the implants were inserted and left only with clot. In Group 2 implants were inserted with the same bone defect and the space filled with Biogran® and in Group 3 the space between bone and implant was filled with Endobon®. The animals were euthanized at 14 and 42 days and there were the histological analysis, histometric (percentage of linear extension bone-implant contact - BIC and bone area - BA), immunohistochemistry (expression of the proteins osteocalcin - OC and osteopontin - OPN) and biomechanics (reverse torque). Results: Histologically all implants were osseointegrated. No statistically significant differences were observed in the values of reverse torque (p> 0.05) at 42 days. For BIC, at 14 days was 8.29; 15.04; and 16.20% for the groups 1, 2 and 3, respectively. After 42 days, the BIC values were 30.84; 33.13; and 13.93% for the same groups, demonstrating that there were no statistical differences between groups, but with different responses between periods. For the quantification of bone formation per area (BA), the response differs between groups. The average BA response in Group 1 (18.75%) did not differ from the average Group 3 response (21.62%). However, different from Group 2 (34.73%). The immunohistochemical results were analyzed by Qualitative...Introdução: A utilização de biomateriais em reconstruções para implantodontia tem sido amplamente discutida nos últimos anos. Proposição: O objetivo deste trabalho foi analisar o comportamento biológico do vidro bioativo (Biogran®) e do osso bovino (Endobon®) durante o processo de osseointegração associados a implantes com defeitos periimplantares em tíbias de rato. Material e método: Foram instalados 75 implantes na tíbia esquerda de 75 ratos Wistar machos. Os implantes foram divididos em três grupos experimentais. No Grupo 1 (Controle) foi provocado um defeito periimplantar monocortical circular e os implantes foram inseridos e deixados apenas com coágulo. No Grupo 2 os implantes foram inseridos com o mesmo defeito ósseo e o espaço preenchido com Biogran® e no Grupo 3 o espaço entre osso e implante foi preenchido com Endobon®. Os animais foram submetidos à eutanásia aos 14 e 42 dias e realizaram-se as análises histológica, histométrica (porcentagem de extensão linear de contato osso-implante - BIC e área óssea - BA), imunoistoquímica (expressão das proteínas osteocalcina - OC e osteopontina - OPN) e biomecânica (torque reverso). Resultados: Histologicamente todos os implantes encontraram-se osseointegrados. Não foram observadas diferenças estatisticamente significantes nos valores de torque reverso (p> 0,05) aos 42 dias. Para BIC, aos 14 dias foi de 8,29; 15,04; e 16,20%, para os grupos 1, 2 e 3, respectivamente. Aos 42 dias, os valores médios de BIC foram 30,84; 33,13; e 13,93% para os mesmos grupos, demonstrando que não houveram diferenças estatísticas entre grupos, porém com respostas diferentes entre períodos. Para a quantificação de formação óssea por área (BA), a resposta entre grupos difere. A resposta da BA média do Grupo 1 (18,75%) não difere da resposta média do Grupo 3 (21,62%). Porém, difere...Universidade Estadual Paulista (Unesp)Magro Filho, Osvaldo [UNESP]Universidade Estadual Paulista (Unesp)Carvalho, Helen Ramon Esper de [UNESP]2016-02-05T18:30:11Z2016-02-05T18:30:11Z2015-09-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis68 f : il. + 1 CD-ROMapplication/pdfCARVALHO, Helen Ramon Esper de. Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares. 2015. 68 f. Tese (doutorado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araçatuba, 2015.http://hdl.handle.net/11449/134207000857959http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/28-01-2016/000857959.pdf33004021011P05535418670745125Alephreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporinfo:eu-repo/semantics/openAccess2023-11-30T06:18:02Zoai:repositorio.unesp.br:11449/134207Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:09:40.448796Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares |
title |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares |
spellingShingle |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares Carvalho, Helen Ramon Esper de [UNESP] Implantes dentários Transplante ósseo Materiais biomédicos Dental implants |
title_short |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares |
title_full |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares |
title_fullStr |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares |
title_full_unstemmed |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares |
title_sort |
Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares |
author |
Carvalho, Helen Ramon Esper de [UNESP] |
author_facet |
Carvalho, Helen Ramon Esper de [UNESP] |
author_role |
author |
dc.contributor.none.fl_str_mv |
Magro Filho, Osvaldo [UNESP] Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Carvalho, Helen Ramon Esper de [UNESP] |
dc.subject.por.fl_str_mv |
Implantes dentários Transplante ósseo Materiais biomédicos Dental implants |
topic |
Implantes dentários Transplante ósseo Materiais biomédicos Dental implants |
description |
Introduction: The use of biomaterials in reconstructions for dental implants has been widely discussed in recent years. Proposition: The aim of this work was to analize the biological behavior of the bioactive glass (Biogran®) and bovine bone (Endobon®) during the osseointegration process associated with implants with peri-implant defects in rat tibia. Material and Methods: 75 implants were installed in the left tibia of 75 male Wistar rats. The implants were divided into three experimental groups. In Group 1 (Control) was caused monocortical circular peri-implant defect and the implants were inserted and left only with clot. In Group 2 implants were inserted with the same bone defect and the space filled with Biogran® and in Group 3 the space between bone and implant was filled with Endobon®. The animals were euthanized at 14 and 42 days and there were the histological analysis, histometric (percentage of linear extension bone-implant contact - BIC and bone area - BA), immunohistochemistry (expression of the proteins osteocalcin - OC and osteopontin - OPN) and biomechanics (reverse torque). Results: Histologically all implants were osseointegrated. No statistically significant differences were observed in the values of reverse torque (p> 0.05) at 42 days. For BIC, at 14 days was 8.29; 15.04; and 16.20% for the groups 1, 2 and 3, respectively. After 42 days, the BIC values were 30.84; 33.13; and 13.93% for the same groups, demonstrating that there were no statistical differences between groups, but with different responses between periods. For the quantification of bone formation per area (BA), the response differs between groups. The average BA response in Group 1 (18.75%) did not differ from the average Group 3 response (21.62%). However, different from Group 2 (34.73%). The immunohistochemical results were analyzed by Qualitative... |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-09-04 2016-02-05T18:30:11Z 2016-02-05T18:30:11Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
CARVALHO, Helen Ramon Esper de. Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares. 2015. 68 f. Tese (doutorado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araçatuba, 2015. http://hdl.handle.net/11449/134207 000857959 http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/28-01-2016/000857959.pdf 33004021011P0 5535418670745125 |
identifier_str_mv |
CARVALHO, Helen Ramon Esper de. Estudo comparativo do Biogran® e Endobon® associados a implantes com defeitos periimplantares. 2015. 68 f. Tese (doutorado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araçatuba, 2015. 000857959 33004021011P0 5535418670745125 |
url |
http://hdl.handle.net/11449/134207 http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/28-01-2016/000857959.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
68 f : il. + 1 CD-ROM application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.source.none.fl_str_mv |
Aleph reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129028051173376 |