Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans

Detalhes bibliográficos
Autor(a) principal: Americo, M. F.
Data de Publicação: 2007
Outros Autores: Oliveira, R. B., Romeiro, Fernando Gomes [UNESP], Baffa, O., Cora, L. A., Miranda, J. R. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
DOI: 10.1111/j.1365-2982.2007.00960.x
Texto Completo: http://dx.doi.org/10.1111/j.1365-2982.2007.00960.x
http://hdl.handle.net/11449/11218
Resumo: Abnormal intragastric distribution of food (IDF) and a phasic contractility in the proximal stomach have been related to dyspeptic symptoms. Thus, the behaviour of the stomach and the proximal region, in particular, continues to attract attention and demand for reliable and comfortable techniques. The aims of this study were to employ AC Biosus-ceptometry (ACB) and scintigraphy to evaluate IDF and gastric motor activity in humans. Fifteen healthy volunteers ingested 60 mL of yogurt containing 2 mCi of Tc-99m and 4 g of ferrite. Each volunteer had gastric motility and IDF evaluated twice on separate days; on one occasion by ACB and another by scintigraphy. Digital signal processing was performed in MatLab (Mathworks Inc., Natick, MA, USA). Results were expressed as mean +/- SD. Similar results of distal accumulation time (P < 0.001) were obtained for scintigraphy (6.93 +/- 3.25 min) and for ACB (7.04 +/- 3.65 min). Fast Fourier Transform revealed two dominant frequencies (P > 0.9). Besides the well-know frequency of 3 cpm, our results showed identical frequencies in proximal stomach recordings (P < 0.001) for scintigraphic (1.01 +/- 0.01 cpm) and ACB (0.98 +/- 0.06 cpm). In summary, our data showed that scintigraphy and ACB are promising techniques to evaluate several aspects of gastric motility. Moreover, ACB is non-invasive, radiation-free and deserves the same importance as conventional methods for this kind of analysis.
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spelling Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humansgastric motilityphasic contractionsproximal stomachvolume wavesAbnormal intragastric distribution of food (IDF) and a phasic contractility in the proximal stomach have been related to dyspeptic symptoms. Thus, the behaviour of the stomach and the proximal region, in particular, continues to attract attention and demand for reliable and comfortable techniques. The aims of this study were to employ AC Biosus-ceptometry (ACB) and scintigraphy to evaluate IDF and gastric motor activity in humans. Fifteen healthy volunteers ingested 60 mL of yogurt containing 2 mCi of Tc-99m and 4 g of ferrite. Each volunteer had gastric motility and IDF evaluated twice on separate days; on one occasion by ACB and another by scintigraphy. Digital signal processing was performed in MatLab (Mathworks Inc., Natick, MA, USA). Results were expressed as mean +/- SD. Similar results of distal accumulation time (P < 0.001) were obtained for scintigraphy (6.93 +/- 3.25 min) and for ACB (7.04 +/- 3.65 min). Fast Fourier Transform revealed two dominant frequencies (P > 0.9). Besides the well-know frequency of 3 cpm, our results showed identical frequencies in proximal stomach recordings (P < 0.001) for scintigraphic (1.01 +/- 0.01 cpm) and ACB (0.98 +/- 0.06 cpm). In summary, our data showed that scintigraphy and ACB are promising techniques to evaluate several aspects of gastric motility. Moreover, ACB is non-invasive, radiation-free and deserves the same importance as conventional methods for this kind of analysis.Univ Estadual Paulista, Lab Biomagnet, Inst Biociencias IBB, Dept Fis & Biofis, BR-18618000 São Paulo, BrazilUniv Estadual Paulista, FMB, Dept Clin Med, BR-18618000 São Paulo, BrazilUniv São Paulo, FFCLRP, Dept Fis & Matemat, São Paulo, BrazilUniv São Paulo, FMRP, Dept Clin Med, São Paulo, BrazilUniv São Paulo, FMRP, Dept Fisiol, São Paulo, BrazilUniv Estadual Paulista, Lab Biomagnet, Inst Biociencias IBB, Dept Fis & Biofis, BR-18618000 São Paulo, BrazilUniv Estadual Paulista, FMB, Dept Clin Med, BR-18618000 São Paulo, BrazilBlackwell PublishingUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Americo, M. F.Oliveira, R. B.Romeiro, Fernando Gomes [UNESP]Baffa, O.Cora, L. A.Miranda, J. R. A.2014-05-20T13:32:51Z2014-05-20T13:32:51Z2007-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article804-811application/pdfhttp://dx.doi.org/10.1111/j.1365-2982.2007.00960.xNeurogastroenterology and Motility. Oxford: Blackwell Publishing, v. 19, n. 10, p. 804-811, 2007.1350-1925http://hdl.handle.net/11449/1121810.1111/j.1365-2982.2007.00960.xWOS:000249845300005WOS000249845300005.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengNeurogastroenterology and Motility3.8422,095info:eu-repo/semantics/openAccess2024-08-14T17:23:33Zoai:repositorio.unesp.br:11449/11218Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T17:23:33Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
title Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
spellingShingle Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
Americo, M. F.
gastric motility
phasic contractions
proximal stomach
volume waves
Americo, M. F.
gastric motility
phasic contractions
proximal stomach
volume waves
title_short Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
title_full Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
title_fullStr Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
title_full_unstemmed Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
title_sort Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
author Americo, M. F.
author_facet Americo, M. F.
Americo, M. F.
Oliveira, R. B.
Romeiro, Fernando Gomes [UNESP]
Baffa, O.
Cora, L. A.
Miranda, J. R. A.
Oliveira, R. B.
Romeiro, Fernando Gomes [UNESP]
Baffa, O.
Cora, L. A.
Miranda, J. R. A.
author_role author
author2 Oliveira, R. B.
Romeiro, Fernando Gomes [UNESP]
Baffa, O.
Cora, L. A.
Miranda, J. R. A.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Americo, M. F.
Oliveira, R. B.
Romeiro, Fernando Gomes [UNESP]
Baffa, O.
Cora, L. A.
Miranda, J. R. A.
dc.subject.por.fl_str_mv gastric motility
phasic contractions
proximal stomach
volume waves
topic gastric motility
phasic contractions
proximal stomach
volume waves
description Abnormal intragastric distribution of food (IDF) and a phasic contractility in the proximal stomach have been related to dyspeptic symptoms. Thus, the behaviour of the stomach and the proximal region, in particular, continues to attract attention and demand for reliable and comfortable techniques. The aims of this study were to employ AC Biosus-ceptometry (ACB) and scintigraphy to evaluate IDF and gastric motor activity in humans. Fifteen healthy volunteers ingested 60 mL of yogurt containing 2 mCi of Tc-99m and 4 g of ferrite. Each volunteer had gastric motility and IDF evaluated twice on separate days; on one occasion by ACB and another by scintigraphy. Digital signal processing was performed in MatLab (Mathworks Inc., Natick, MA, USA). Results were expressed as mean +/- SD. Similar results of distal accumulation time (P < 0.001) were obtained for scintigraphy (6.93 +/- 3.25 min) and for ACB (7.04 +/- 3.65 min). Fast Fourier Transform revealed two dominant frequencies (P > 0.9). Besides the well-know frequency of 3 cpm, our results showed identical frequencies in proximal stomach recordings (P < 0.001) for scintigraphic (1.01 +/- 0.01 cpm) and ACB (0.98 +/- 0.06 cpm). In summary, our data showed that scintigraphy and ACB are promising techniques to evaluate several aspects of gastric motility. Moreover, ACB is non-invasive, radiation-free and deserves the same importance as conventional methods for this kind of analysis.
publishDate 2007
dc.date.none.fl_str_mv 2007-10-01
2014-05-20T13:32:51Z
2014-05-20T13:32:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1111/j.1365-2982.2007.00960.x
Neurogastroenterology and Motility. Oxford: Blackwell Publishing, v. 19, n. 10, p. 804-811, 2007.
1350-1925
http://hdl.handle.net/11449/11218
10.1111/j.1365-2982.2007.00960.x
WOS:000249845300005
WOS000249845300005.pdf
url http://dx.doi.org/10.1111/j.1365-2982.2007.00960.x
http://hdl.handle.net/11449/11218
identifier_str_mv Neurogastroenterology and Motility. Oxford: Blackwell Publishing, v. 19, n. 10, p. 804-811, 2007.
1350-1925
10.1111/j.1365-2982.2007.00960.x
WOS:000249845300005
WOS000249845300005.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Neurogastroenterology and Motility
3.842
2,095
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 804-811
application/pdf
dc.publisher.none.fl_str_mv Blackwell Publishing
publisher.none.fl_str_mv Blackwell Publishing
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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dc.identifier.doi.none.fl_str_mv 10.1111/j.1365-2982.2007.00960.x