Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.21037/tgh-22-48 http://hdl.handle.net/11449/245482 |
Resumo: | Background: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplastic disease of varied presentation and unspecific radiological signs in the early stages. The diagnostic delay can lead to metastatic disease, thus increasing the tumor burden and reducing the treatment options. HEHE is usually deemed a slow-growing tumor, but its speed of growth is poorly reported and still unknown.Case Description: In this case report, we documented a HEHE diagnosed in a young woman who had complaints of abdominal pain, weight loss and bloating for a long time. The typical findings observed in histological studies were not promptly recognized in the histological analyzes, even after two laparoscopicguided liver biopsies, delaying the diagnosis until extrahepatic tumor spreading. Findings observed in computed tomography, magnetic resonance imaging and histological studies are presented. The coalescence of nodules and the rising of giant masses, occupying large parts of the liver in a specific time span, were registered and quantified. As opposed to prior reports, the results show that hepatic HEHE can grow rapidly, reinforcing the need of early diagnosis, thus avoiding the complications presented herein.Conclusions: The findings observed via radiological and histological imaging that could have avoided the diagnosis delay are depicted and discussed, showing that HEHE can rise faster than previously documented. |
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Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case reportLiver cancerextrahepatic metastasisimagingliver neoplasmscase reportBackground: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplastic disease of varied presentation and unspecific radiological signs in the early stages. The diagnostic delay can lead to metastatic disease, thus increasing the tumor burden and reducing the treatment options. HEHE is usually deemed a slow-growing tumor, but its speed of growth is poorly reported and still unknown.Case Description: In this case report, we documented a HEHE diagnosed in a young woman who had complaints of abdominal pain, weight loss and bloating for a long time. The typical findings observed in histological studies were not promptly recognized in the histological analyzes, even after two laparoscopicguided liver biopsies, delaying the diagnosis until extrahepatic tumor spreading. Findings observed in computed tomography, magnetic resonance imaging and histological studies are presented. The coalescence of nodules and the rising of giant masses, occupying large parts of the liver in a specific time span, were registered and quantified. As opposed to prior reports, the results show that hepatic HEHE can grow rapidly, reinforcing the need of early diagnosis, thus avoiding the complications presented herein.Conclusions: The findings observed via radiological and histological imaging that could have avoided the diagnosis delay are depicted and discussed, showing that HEHE can rise faster than previously documented.Funda��o de Amparo � Pesquisa do Estado de S�o Paulo (FAPESP)Conselho Nacional de Desenvolvimento Cient�fico e Tecnol�gico (CNPq)Univ Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Botucatu, BrazilHosp Estadual Bauru, Fundacao Desenvolvimento Med & Hosp FAMESP, Bauru, BrazilUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Pathol, Botucatu, BrazilUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Radiol, Botucatu, BrazilClin Hosp, Ctr Med Phys & Radiat Protect, FMB HC, Botucatu Sch Med, Botucatu, BrazilGen Hosp Shenyang Mil Area, Gen Hosp Northern Theater Command, Dept Gastroenterol, Shenyang, Peoples R ChinaSao Paulo State Univ UNSEP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Dist Rubiao Jr S N, BR-18608917 Sao Paulo, BrazilUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Botucatu, BrazilUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Pathol, Botucatu, BrazilUniv Estadual Paulista Julio Mesquita Filho UNESP, Botucatu Sch Med, Dept Radiol, Botucatu, BrazilSao Paulo State Univ UNSEP, Botucatu Sch Med, Dept Internal Med, Gastroenterol Div, Dist Rubiao Jr S N, BR-18608917 Sao Paulo, BrazilFAPESP: 2017/25592-9)Ame Publishing CompanyUniversidade Estadual Paulista (UNESP)Hosp Estadual BauruClin HospGen Hosp Shenyang Mil AreaRibeiro, Michele Costa de Oliveira [UNESP]Lemos, Juliana Viana BaiaoMoraes, Marcelo Padovani de Toledo [UNESP]Oliver, Felipe Aguera [UNESP]Alvarez, MatheusSilva, Giovanni Faria [UNESP]Qi, XingshunRomeiro, Fernando Gomes [UNESP]2023-07-29T11:56:15Z2023-07-29T11:56:15Z2022-07-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9http://dx.doi.org/10.21037/tgh-22-48Translational Gastroenterology and Hepatology. Shatin: Ame Publishing Company, 9 p., 2022.http://hdl.handle.net/11449/24548210.21037/tgh-22-48WOS:000874989700001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTranslational Gastroenterology And Hepatologyinfo:eu-repo/semantics/openAccess2023-07-29T11:56:15Zoai:repositorio.unesp.br:11449/245482Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-07-29T11:56:15Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report |
title |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report |
spellingShingle |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report Ribeiro, Michele Costa de Oliveira [UNESP] Liver cancer extrahepatic metastasis imaging liver neoplasms case report |
title_short |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report |
title_full |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report |
title_fullStr |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report |
title_full_unstemmed |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report |
title_sort |
Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report |
author |
Ribeiro, Michele Costa de Oliveira [UNESP] |
author_facet |
Ribeiro, Michele Costa de Oliveira [UNESP] Lemos, Juliana Viana Baiao Moraes, Marcelo Padovani de Toledo [UNESP] Oliver, Felipe Aguera [UNESP] Alvarez, Matheus Silva, Giovanni Faria [UNESP] Qi, Xingshun Romeiro, Fernando Gomes [UNESP] |
author_role |
author |
author2 |
Lemos, Juliana Viana Baiao Moraes, Marcelo Padovani de Toledo [UNESP] Oliver, Felipe Aguera [UNESP] Alvarez, Matheus Silva, Giovanni Faria [UNESP] Qi, Xingshun Romeiro, Fernando Gomes [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Hosp Estadual Bauru Clin Hosp Gen Hosp Shenyang Mil Area |
dc.contributor.author.fl_str_mv |
Ribeiro, Michele Costa de Oliveira [UNESP] Lemos, Juliana Viana Baiao Moraes, Marcelo Padovani de Toledo [UNESP] Oliver, Felipe Aguera [UNESP] Alvarez, Matheus Silva, Giovanni Faria [UNESP] Qi, Xingshun Romeiro, Fernando Gomes [UNESP] |
dc.subject.por.fl_str_mv |
Liver cancer extrahepatic metastasis imaging liver neoplasms case report |
topic |
Liver cancer extrahepatic metastasis imaging liver neoplasms case report |
description |
Background: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplastic disease of varied presentation and unspecific radiological signs in the early stages. The diagnostic delay can lead to metastatic disease, thus increasing the tumor burden and reducing the treatment options. HEHE is usually deemed a slow-growing tumor, but its speed of growth is poorly reported and still unknown.Case Description: In this case report, we documented a HEHE diagnosed in a young woman who had complaints of abdominal pain, weight loss and bloating for a long time. The typical findings observed in histological studies were not promptly recognized in the histological analyzes, even after two laparoscopicguided liver biopsies, delaying the diagnosis until extrahepatic tumor spreading. Findings observed in computed tomography, magnetic resonance imaging and histological studies are presented. The coalescence of nodules and the rising of giant masses, occupying large parts of the liver in a specific time span, were registered and quantified. As opposed to prior reports, the results show that hepatic HEHE can grow rapidly, reinforcing the need of early diagnosis, thus avoiding the complications presented herein.Conclusions: The findings observed via radiological and histological imaging that could have avoided the diagnosis delay are depicted and discussed, showing that HEHE can rise faster than previously documented. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-29 2023-07-29T11:56:15Z 2023-07-29T11:56:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.21037/tgh-22-48 Translational Gastroenterology and Hepatology. Shatin: Ame Publishing Company, 9 p., 2022. http://hdl.handle.net/11449/245482 10.21037/tgh-22-48 WOS:000874989700001 |
url |
http://dx.doi.org/10.21037/tgh-22-48 http://hdl.handle.net/11449/245482 |
identifier_str_mv |
Translational Gastroenterology and Hepatology. Shatin: Ame Publishing Company, 9 p., 2022. 10.21037/tgh-22-48 WOS:000874989700001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Translational Gastroenterology And Hepatology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
9 |
dc.publisher.none.fl_str_mv |
Ame Publishing Company |
publisher.none.fl_str_mv |
Ame Publishing Company |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803046343984283648 |