Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV

Detalhes bibliográficos
Autor(a) principal: Sacilotto, Livia Bertazzo [UNESP]
Data de Publicação: 2017
Outros Autores: Pereira, Paulo Câmara Marques [UNESP], Manechini, João Paulo Vieira, Papini, Sílvia Justina [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1155/2017/8260867
http://hdl.handle.net/11449/178882
Resumo: HIV-associated lipodystrophy syndrome (HALS) is characterized by body fat redistribution as a consequence of the antiretroviral therapy (ART) introduction, associated with an increased risk of cardiovascular disease development. Subjective diagnosis, classified between three subtypes according to the body region on which fat is lost and/or accumulated, named lipoatrophy, lipohypertrophy, and mixed lipodystrophy, is possibly accompanied with metabolic alterations. Forty people living with HIV/AIDS (PLHA), with clinical diagnosis of HALS and from both genders, were assessed. They performed ambulatorial follow-up and used ART regularly. The main findings were greater lipid profile alterations among women, while no metabolic profile differences were found between the HALS subtypes. The lipohypertrophy group showed major alterations, with higher values for total body fat percent, visceral fat area (VFA), body mass index (BMI), and abdominal and neck circumferences when compared to the other groups. Lean body mass was superior only compared to the mixed lipodystrophy group, and fat mass only compared to the lipoatrophy group. BMI showed strong correlation with the VFA. In conclusion, despite anthropometric alterations related to HALS these individuals present, those are not accompanied with metabolic alterations. Strategies, as behavioral changes and disorders prevention, are important to decrease the risk of cardiovascular disease development.
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spelling Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIVHIV-associated lipodystrophy syndrome (HALS) is characterized by body fat redistribution as a consequence of the antiretroviral therapy (ART) introduction, associated with an increased risk of cardiovascular disease development. Subjective diagnosis, classified between three subtypes according to the body region on which fat is lost and/or accumulated, named lipoatrophy, lipohypertrophy, and mixed lipodystrophy, is possibly accompanied with metabolic alterations. Forty people living with HIV/AIDS (PLHA), with clinical diagnosis of HALS and from both genders, were assessed. They performed ambulatorial follow-up and used ART regularly. The main findings were greater lipid profile alterations among women, while no metabolic profile differences were found between the HALS subtypes. The lipohypertrophy group showed major alterations, with higher values for total body fat percent, visceral fat area (VFA), body mass index (BMI), and abdominal and neck circumferences when compared to the other groups. Lean body mass was superior only compared to the mixed lipodystrophy group, and fat mass only compared to the lipoatrophy group. BMI showed strong correlation with the VFA. In conclusion, despite anthropometric alterations related to HALS these individuals present, those are not accompanied with metabolic alterations. Strategies, as behavioral changes and disorders prevention, are important to decrease the risk of cardiovascular disease development.Botucatu Medical School São Paulo State University (UNESP)Ribeirao Preto Medical School University of São Paulo (USP)Botucatu Medical School São Paulo State University (UNESP)Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Sacilotto, Livia Bertazzo [UNESP]Pereira, Paulo Câmara Marques [UNESP]Manechini, João Paulo VieiraPapini, Sílvia Justina [UNESP]2018-12-11T17:32:32Z2018-12-11T17:32:32Z2017-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1155/2017/8260867Journal of Nutrition and Metabolism, v. 2017.2090-07322090-0724http://hdl.handle.net/11449/17888210.1155/2017/82608672-s2.0-850196062272-s2.0-85019606227.pdf13653204274182040000-0001-5771-8943Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Nutrition and Metabolism0,6810,681info:eu-repo/semantics/openAccess2024-08-15T15:23:16Zoai:repositorio.unesp.br:11449/178882Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-15T15:23:16Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
title Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
spellingShingle Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
Sacilotto, Livia Bertazzo [UNESP]
title_short Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
title_full Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
title_fullStr Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
title_full_unstemmed Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
title_sort Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
author Sacilotto, Livia Bertazzo [UNESP]
author_facet Sacilotto, Livia Bertazzo [UNESP]
Pereira, Paulo Câmara Marques [UNESP]
Manechini, João Paulo Vieira
Papini, Sílvia Justina [UNESP]
author_role author
author2 Pereira, Paulo Câmara Marques [UNESP]
Manechini, João Paulo Vieira
Papini, Sílvia Justina [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Sacilotto, Livia Bertazzo [UNESP]
Pereira, Paulo Câmara Marques [UNESP]
Manechini, João Paulo Vieira
Papini, Sílvia Justina [UNESP]
description HIV-associated lipodystrophy syndrome (HALS) is characterized by body fat redistribution as a consequence of the antiretroviral therapy (ART) introduction, associated with an increased risk of cardiovascular disease development. Subjective diagnosis, classified between three subtypes according to the body region on which fat is lost and/or accumulated, named lipoatrophy, lipohypertrophy, and mixed lipodystrophy, is possibly accompanied with metabolic alterations. Forty people living with HIV/AIDS (PLHA), with clinical diagnosis of HALS and from both genders, were assessed. They performed ambulatorial follow-up and used ART regularly. The main findings were greater lipid profile alterations among women, while no metabolic profile differences were found between the HALS subtypes. The lipohypertrophy group showed major alterations, with higher values for total body fat percent, visceral fat area (VFA), body mass index (BMI), and abdominal and neck circumferences when compared to the other groups. Lean body mass was superior only compared to the mixed lipodystrophy group, and fat mass only compared to the lipoatrophy group. BMI showed strong correlation with the VFA. In conclusion, despite anthropometric alterations related to HALS these individuals present, those are not accompanied with metabolic alterations. Strategies, as behavioral changes and disorders prevention, are important to decrease the risk of cardiovascular disease development.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
2018-12-11T17:32:32Z
2018-12-11T17:32:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1155/2017/8260867
Journal of Nutrition and Metabolism, v. 2017.
2090-0732
2090-0724
http://hdl.handle.net/11449/178882
10.1155/2017/8260867
2-s2.0-85019606227
2-s2.0-85019606227.pdf
1365320427418204
0000-0001-5771-8943
url http://dx.doi.org/10.1155/2017/8260867
http://hdl.handle.net/11449/178882
identifier_str_mv Journal of Nutrition and Metabolism, v. 2017.
2090-0732
2090-0724
10.1155/2017/8260867
2-s2.0-85019606227
2-s2.0-85019606227.pdf
1365320427418204
0000-0001-5771-8943
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Nutrition and Metabolism
0,681
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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