The role of oxidative stress in renal injury related to obesity

Detalhes bibliográficos
Autor(a) principal: Pierine, Damiana Tortolero [UNESP]
Data de Publicação: 2015
Outros Autores: Biondo, Guilherme Augusto [UNESP], Silva, Vanessa dos Santos [UNESP], Corrêa, Camila Renata [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.14800/ics.648
http://hdl.handle.net/11449/136977
Resumo: The mechanisms linking obesity to kidney damage are unknown. AGEs are responsible for renal damage in obese individuals. The receptor AGEs (RAGE) contributes to nuclear transcription factors that result in the production of proinflammatory cytokines and this seems to contribute to the development of renal disease. Thus, intervention with antioxidant can have an important effect in the prevention and treatment of pro-oxidant and pro-inflammatory state in the kidneys resulting from obesity.
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spelling The role of oxidative stress in renal injury related to obesityObesityKidneyOxidative stressAGEsRAGEInflammatory markersThe mechanisms linking obesity to kidney damage are unknown. AGEs are responsible for renal damage in obese individuals. The receptor AGEs (RAGE) contributes to nuclear transcription factors that result in the production of proinflammatory cytokines and this seems to contribute to the development of renal disease. Thus, intervention with antioxidant can have an important effect in the prevention and treatment of pro-oxidant and pro-inflammatory state in the kidneys resulting from obesity.Universidade Estadual Paulista, Departamento de Patologia, Faculdade de Medicina de BotucatuUniversidade Estadual Paulista, Departamento de Microbiologia e Imunologia, Instituto de Biociências de BotucatuUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de BotucatuUniversidade Estadual Paulista (Unesp)Pierine, Damiana Tortolero [UNESP]Biondo, Guilherme Augusto [UNESP]Silva, Vanessa dos Santos [UNESP]Corrêa, Camila Renata [UNESP]2016-04-01T18:43:37Z2016-04-01T18:43:37Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-4application/pdfhttp://dx.doi.org/10.14800/ics.648Inflammation & Cell Signaling, v. 2, p. 1-4, 2015.2330-7803http://hdl.handle.net/11449/13697710.14800/ics.648ISSN2330-7803-2015-02-01-04.pdf85152652573100644868745446773753Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInflammation & Cell Signalinginfo:eu-repo/semantics/openAccess2024-09-03T13:14:07Zoai:repositorio.unesp.br:11449/136977Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T13:14:07Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The role of oxidative stress in renal injury related to obesity
title The role of oxidative stress in renal injury related to obesity
spellingShingle The role of oxidative stress in renal injury related to obesity
Pierine, Damiana Tortolero [UNESP]
Obesity
Kidney
Oxidative stress
AGEs
RAGE
Inflammatory markers
title_short The role of oxidative stress in renal injury related to obesity
title_full The role of oxidative stress in renal injury related to obesity
title_fullStr The role of oxidative stress in renal injury related to obesity
title_full_unstemmed The role of oxidative stress in renal injury related to obesity
title_sort The role of oxidative stress in renal injury related to obesity
author Pierine, Damiana Tortolero [UNESP]
author_facet Pierine, Damiana Tortolero [UNESP]
Biondo, Guilherme Augusto [UNESP]
Silva, Vanessa dos Santos [UNESP]
Corrêa, Camila Renata [UNESP]
author_role author
author2 Biondo, Guilherme Augusto [UNESP]
Silva, Vanessa dos Santos [UNESP]
Corrêa, Camila Renata [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Pierine, Damiana Tortolero [UNESP]
Biondo, Guilherme Augusto [UNESP]
Silva, Vanessa dos Santos [UNESP]
Corrêa, Camila Renata [UNESP]
dc.subject.por.fl_str_mv Obesity
Kidney
Oxidative stress
AGEs
RAGE
Inflammatory markers
topic Obesity
Kidney
Oxidative stress
AGEs
RAGE
Inflammatory markers
description The mechanisms linking obesity to kidney damage are unknown. AGEs are responsible for renal damage in obese individuals. The receptor AGEs (RAGE) contributes to nuclear transcription factors that result in the production of proinflammatory cytokines and this seems to contribute to the development of renal disease. Thus, intervention with antioxidant can have an important effect in the prevention and treatment of pro-oxidant and pro-inflammatory state in the kidneys resulting from obesity.
publishDate 2015
dc.date.none.fl_str_mv 2015
2016-04-01T18:43:37Z
2016-04-01T18:43:37Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.14800/ics.648
Inflammation & Cell Signaling, v. 2, p. 1-4, 2015.
2330-7803
http://hdl.handle.net/11449/136977
10.14800/ics.648
ISSN2330-7803-2015-02-01-04.pdf
8515265257310064
4868745446773753
url http://dx.doi.org/10.14800/ics.648
http://hdl.handle.net/11449/136977
identifier_str_mv Inflammation & Cell Signaling, v. 2, p. 1-4, 2015.
2330-7803
10.14800/ics.648
ISSN2330-7803-2015-02-01-04.pdf
8515265257310064
4868745446773753
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Inflammation & Cell Signaling
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-4
application/pdf
dc.source.none.fl_str_mv Currículo Lattes
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1810021355479891968

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