Eletrocardiografia de cães submetidos a diferentes concentrações de desflurano, pré-tratados ou não com a associação de fentanil/droperidol

• Autor(a) principal: Santos, Paulo Sérgio Patto Dos
• Data de Publicação: 2001
• Outros Autores: Nunes, Newton, Vicenti, Felipe Antônio Mendes, Martins, Silvio Emílio Cuevas, Rezende, Márlis Langenegger De
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/S0103-84782001000500011; http://hdl.handle.net/11449/211475
• topic: electrocardiography; MAC; desflurane; fentanyl; droperidol; dogs; eletrocardiografia; CAM; desflurano; fentanil; droperidol; cães

The aim of this work was to evaluate the effects of the fentanil/droperidol association over the heart rate (HR) and electrocardiography (ECG) of dogs submitted to anesthesia by desflurane. For that, forty healthy adult dogs, males and females were used. The dogs were equally separate in two groups G1 and G2. G1 received fentanil (15.7mg/kg) associated to droperidol (0.5mg/kg); while G2 received saline solution at 0.9% (placebo), both applied intravenously. After 15 minutes the general anesthesia was induced with intravenously administration of propofol (5mg/kg). The dogs were submitted to inhalatory anesthesia with desflurane, with an initial concentration of 1.6 MAC. The observations of the variables were begun immediately before the application of the agents (M1). New measurings were carried out 15 minutes after the administration of the fentanil/droperidol association or placebo (M2) and 20 minutes after the anesthetic induction (M3). The other measurings coincided with the establishment of the concentrations of 1.4; 1.2 and 1.0 MAC, respectively M4 to M6. The numeric data were submitted to the Analysis of Profile, being considered the level of significance of p<0.05. The results allowed to conclude that the fentanil/droperidol association decreases HR and the desflurane blocks the decrease on HR produced by the association and promoves a delay in the electrical atrial and ventricular conduction.