Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.

Detalhes bibliográficos
Autor(a) principal: Okoshi, M. P.
Data de Publicação: 1995
Outros Autores: Ferreira Tucci, P. J., Okoshi, K., Padovani, C. R., Cicogna, A. C.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdf
http://hdl.handle.net/11449/64647
Resumo: PURPOSE: To evaluate the effects of afterload on peak rate of tension rise (dT/dt) in the isolated muscle. METHODS: Left ventricular papillary muscles from Wistar rats were studied in isometric and isotonic afterloaded contractions. Muscles were analised in Krebs-Henseleit solution with calcium concentration of 2.52mM at 28 degrees C. The resting muscle length (preload) was maintained constant. The peak isometric developed tension (DT) and dT/dt were measured during increases of afterload (25, 50, 75 and 100% from DT). RESULTS: A rise in afterload corresponding to 50, 75 and 100% of DT, did not cause an increase in dT/dt values (p > 0.05). The dT/dt value decreased (p < 0.05) when afterload was changed from 75% to 25% of DT. CONCLUSION: The data suggest that an increase in the afterload from 50% of the DT did not promote changes in the dT/dt.
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spelling Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.Influence of afterload on the rate of variation of developed pressure (dT/dt). Study in isolated cardiac muscleanimalheart contractionheart outputheart papillary musclemalemuscle isometric contractionphysiologyratWistar ratAnimalsCardiac OutputIsometric ContractionMaleMyocardial ContractionPapillary MusclesRatsRats, WistarPURPOSE: To evaluate the effects of afterload on peak rate of tension rise (dT/dt) in the isolated muscle. METHODS: Left ventricular papillary muscles from Wistar rats were studied in isometric and isotonic afterloaded contractions. Muscles were analised in Krebs-Henseleit solution with calcium concentration of 2.52mM at 28 degrees C. The resting muscle length (preload) was maintained constant. The peak isometric developed tension (DT) and dT/dt were measured during increases of afterload (25, 50, 75 and 100% from DT). RESULTS: A rise in afterload corresponding to 50, 75 and 100% of DT, did not cause an increase in dT/dt values (p > 0.05). The dT/dt value decreased (p < 0.05) when afterload was changed from 75% to 25% of DT. CONCLUSION: The data suggest that an increase in the afterload from 50% of the DT did not promote changes in the dT/dt.Universidade Estadual Paulista (Unesp)Okoshi, M. P.Ferreira Tucci, P. J.Okoshi, K.Padovani, C. R.Cicogna, A. C.2014-05-27T11:18:01Z2014-05-27T11:18:01Z1995-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article417-421application/pdfhttp://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdfArquivos brasileiros de cardiologia, v. 65, n. 5, p. 417-421, 1995.0066-782Xhttp://hdl.handle.net/11449/646472-s2.0-00294025602-s2.0-0029402560.pdf8727897080522289Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporArquivos Brasileiros de Cardiologia1.318info:eu-repo/semantics/openAccess2024-01-28T06:47:30Zoai:repositorio.unesp.br:11449/64647Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-06T00:08:16.007524Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
Influence of afterload on the rate of variation of developed pressure (dT/dt). Study in isolated cardiac muscle
title Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
spellingShingle Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
Okoshi, M. P.
animal
heart contraction
heart output
heart papillary muscle
male
muscle isometric contraction
physiology
rat
Wistar rat
Animals
Cardiac Output
Isometric Contraction
Male
Myocardial Contraction
Papillary Muscles
Rats
Rats, Wistar
title_short Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
title_full Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
title_fullStr Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
title_full_unstemmed Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
title_sort Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
author Okoshi, M. P.
author_facet Okoshi, M. P.
Ferreira Tucci, P. J.
Okoshi, K.
Padovani, C. R.
Cicogna, A. C.
author_role author
author2 Ferreira Tucci, P. J.
Okoshi, K.
Padovani, C. R.
Cicogna, A. C.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Okoshi, M. P.
Ferreira Tucci, P. J.
Okoshi, K.
Padovani, C. R.
Cicogna, A. C.
dc.subject.por.fl_str_mv animal
heart contraction
heart output
heart papillary muscle
male
muscle isometric contraction
physiology
rat
Wistar rat
Animals
Cardiac Output
Isometric Contraction
Male
Myocardial Contraction
Papillary Muscles
Rats
Rats, Wistar
topic animal
heart contraction
heart output
heart papillary muscle
male
muscle isometric contraction
physiology
rat
Wistar rat
Animals
Cardiac Output
Isometric Contraction
Male
Myocardial Contraction
Papillary Muscles
Rats
Rats, Wistar
description PURPOSE: To evaluate the effects of afterload on peak rate of tension rise (dT/dt) in the isolated muscle. METHODS: Left ventricular papillary muscles from Wistar rats were studied in isometric and isotonic afterloaded contractions. Muscles were analised in Krebs-Henseleit solution with calcium concentration of 2.52mM at 28 degrees C. The resting muscle length (preload) was maintained constant. The peak isometric developed tension (DT) and dT/dt were measured during increases of afterload (25, 50, 75 and 100% from DT). RESULTS: A rise in afterload corresponding to 50, 75 and 100% of DT, did not cause an increase in dT/dt values (p > 0.05). The dT/dt value decreased (p < 0.05) when afterload was changed from 75% to 25% of DT. CONCLUSION: The data suggest that an increase in the afterload from 50% of the DT did not promote changes in the dT/dt.
publishDate 1995
dc.date.none.fl_str_mv 1995-11-01
2014-05-27T11:18:01Z
2014-05-27T11:18:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdf
Arquivos brasileiros de cardiologia, v. 65, n. 5, p. 417-421, 1995.
0066-782X
http://hdl.handle.net/11449/64647
2-s2.0-0029402560
2-s2.0-0029402560.pdf
8727897080522289
url http://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdf
http://hdl.handle.net/11449/64647
identifier_str_mv Arquivos brasileiros de cardiologia, v. 65, n. 5, p. 417-421, 1995.
0066-782X
2-s2.0-0029402560
2-s2.0-0029402560.pdf
8727897080522289
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Arquivos Brasileiros de Cardiologia
1.318
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 417-421
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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