Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
Autor(a) principal: | |
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Data de Publicação: | 1995 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdf http://hdl.handle.net/11449/64647 |
Resumo: | PURPOSE: To evaluate the effects of afterload on peak rate of tension rise (dT/dt) in the isolated muscle. METHODS: Left ventricular papillary muscles from Wistar rats were studied in isometric and isotonic afterloaded contractions. Muscles were analised in Krebs-Henseleit solution with calcium concentration of 2.52mM at 28 degrees C. The resting muscle length (preload) was maintained constant. The peak isometric developed tension (DT) and dT/dt were measured during increases of afterload (25, 50, 75 and 100% from DT). RESULTS: A rise in afterload corresponding to 50, 75 and 100% of DT, did not cause an increase in dT/dt values (p > 0.05). The dT/dt value decreased (p < 0.05) when afterload was changed from 75% to 25% of DT. CONCLUSION: The data suggest that an increase in the afterload from 50% of the DT did not promote changes in the dT/dt. |
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Repositório Institucional da UNESP |
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Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.Influence of afterload on the rate of variation of developed pressure (dT/dt). Study in isolated cardiac muscleanimalheart contractionheart outputheart papillary musclemalemuscle isometric contractionphysiologyratWistar ratAnimalsCardiac OutputIsometric ContractionMaleMyocardial ContractionPapillary MusclesRatsRats, WistarPURPOSE: To evaluate the effects of afterload on peak rate of tension rise (dT/dt) in the isolated muscle. METHODS: Left ventricular papillary muscles from Wistar rats were studied in isometric and isotonic afterloaded contractions. Muscles were analised in Krebs-Henseleit solution with calcium concentration of 2.52mM at 28 degrees C. The resting muscle length (preload) was maintained constant. The peak isometric developed tension (DT) and dT/dt were measured during increases of afterload (25, 50, 75 and 100% from DT). RESULTS: A rise in afterload corresponding to 50, 75 and 100% of DT, did not cause an increase in dT/dt values (p > 0.05). The dT/dt value decreased (p < 0.05) when afterload was changed from 75% to 25% of DT. CONCLUSION: The data suggest that an increase in the afterload from 50% of the DT did not promote changes in the dT/dt.Universidade Estadual Paulista (Unesp)Okoshi, M. P.Ferreira Tucci, P. J.Okoshi, K.Padovani, C. R.Cicogna, A. C.2014-05-27T11:18:01Z2014-05-27T11:18:01Z1995-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article417-421application/pdfhttp://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdfArquivos brasileiros de cardiologia, v. 65, n. 5, p. 417-421, 1995.0066-782Xhttp://hdl.handle.net/11449/646472-s2.0-00294025602-s2.0-0029402560.pdf8727897080522289Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporArquivos Brasileiros de Cardiologia1.318info:eu-repo/semantics/openAccess2024-01-28T06:47:30Zoai:repositorio.unesp.br:11449/64647Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-06T00:08:16.007524Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. Influence of afterload on the rate of variation of developed pressure (dT/dt). Study in isolated cardiac muscle |
title |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. |
spellingShingle |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. Okoshi, M. P. animal heart contraction heart output heart papillary muscle male muscle isometric contraction physiology rat Wistar rat Animals Cardiac Output Isometric Contraction Male Myocardial Contraction Papillary Muscles Rats Rats, Wistar |
title_short |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. |
title_full |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. |
title_fullStr |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. |
title_full_unstemmed |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. |
title_sort |
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado. |
author |
Okoshi, M. P. |
author_facet |
Okoshi, M. P. Ferreira Tucci, P. J. Okoshi, K. Padovani, C. R. Cicogna, A. C. |
author_role |
author |
author2 |
Ferreira Tucci, P. J. Okoshi, K. Padovani, C. R. Cicogna, A. C. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Okoshi, M. P. Ferreira Tucci, P. J. Okoshi, K. Padovani, C. R. Cicogna, A. C. |
dc.subject.por.fl_str_mv |
animal heart contraction heart output heart papillary muscle male muscle isometric contraction physiology rat Wistar rat Animals Cardiac Output Isometric Contraction Male Myocardial Contraction Papillary Muscles Rats Rats, Wistar |
topic |
animal heart contraction heart output heart papillary muscle male muscle isometric contraction physiology rat Wistar rat Animals Cardiac Output Isometric Contraction Male Myocardial Contraction Papillary Muscles Rats Rats, Wistar |
description |
PURPOSE: To evaluate the effects of afterload on peak rate of tension rise (dT/dt) in the isolated muscle. METHODS: Left ventricular papillary muscles from Wistar rats were studied in isometric and isotonic afterloaded contractions. Muscles were analised in Krebs-Henseleit solution with calcium concentration of 2.52mM at 28 degrees C. The resting muscle length (preload) was maintained constant. The peak isometric developed tension (DT) and dT/dt were measured during increases of afterload (25, 50, 75 and 100% from DT). RESULTS: A rise in afterload corresponding to 50, 75 and 100% of DT, did not cause an increase in dT/dt values (p > 0.05). The dT/dt value decreased (p < 0.05) when afterload was changed from 75% to 25% of DT. CONCLUSION: The data suggest that an increase in the afterload from 50% of the DT did not promote changes in the dT/dt. |
publishDate |
1995 |
dc.date.none.fl_str_mv |
1995-11-01 2014-05-27T11:18:01Z 2014-05-27T11:18:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdf Arquivos brasileiros de cardiologia, v. 65, n. 5, p. 417-421, 1995. 0066-782X http://hdl.handle.net/11449/64647 2-s2.0-0029402560 2-s2.0-0029402560.pdf 8727897080522289 |
url |
http://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdf http://hdl.handle.net/11449/64647 |
identifier_str_mv |
Arquivos brasileiros de cardiologia, v. 65, n. 5, p. 417-421, 1995. 0066-782X 2-s2.0-0029402560 2-s2.0-0029402560.pdf 8727897080522289 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia 1.318 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
417-421 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129588564328448 |