Anthropometric, functional capacity, and oxidative stress changes in Brazilian community-living elderly subjects. A longitudinal study

• Autor(a) principal: Moreira, Priscila Lucelia [UNESP]
• Data de Publicação: 2016
• Outros Autores: Correa, Camila Renata [UNESP], Corrente, José Eduardo [UNESP], Martin, Luis Cuadrado [UNESP], Boas, Paulo Jose Fortes Villas [UNESP], Ferreira, Ana Lucia Anjos [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1016/j.archger.2016.05.013; http://hdl.handle.net/11449/173086
• topic: Anthropometry; Arthritis; Brazilian elderly; Disability; Hypertension; Oxidative stress

Objective: To examine the changes and relationships among anthropometric, functional and plasma oxidative stress markers in elderly. Design: longitudinal study. Setting: measurements in 2008 and 2010. Participants: 103 community-dwelling men and women aged 67-92. Measurements: Anthropometric parameters [waist, hip, arm and calf circumferences; waist-hip ratio, triceps skinfold thickness and others], basic (ADL) and instrumental activities of daily living (IADL)] and plasma oxidative stress markers (α-tocopherol, β-carotene and malondialdehyde) were assessed in 2008 and 2010. Results: ADL, IADL, body weight, skinfold thickness and circumferences of calf and arm decreased and waist and waist-hip ratio increased from 2008 to 2010. α-Tocopherol decreased and malondialdehyde plasma levels increased during the study period. In multiple logistic regression analyses, increased age (OR = 1.12; IC: 1.02-1.23; p = 0.02), female gender (OR = 8.43; IC: 1.23-57.58; p = 0.03), hypertension (OR = 0.22; IC: 0.06-0.79; p = 0.02), arthritis/arthrosis (OR = 0.09; IC: 0.009-0.87; p = 0.04) and depression (OR = 0.20; IC: 0.04-1.03; p = 0.05) were independent risk factors for functional decline. Conclusion: Fat reduction, muscle loss, central obesity increase, functional decline and worsening of plasma oxidative stress were observed during 2-year follow-up. Some of the risk factors that were identified could be modified to help prevent functional decline in elderly. The factors deserving attention include hypertension, arthritis/arthrosis and depression.