Influence of different durations of estrogen deficiency on alveolar bone loss in rats
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1806-83242011000600011 http://hdl.handle.net/11449/22667 |
Resumo: | The purpose of this study was to morphometrically evaluate the influence of different durations of ovariectomy-induced estrogen deficiency on alveolar bone loss associated with ligature-induced bone loss in rats. Sixty female Wistar rats were randomly assigned to ovariectomy (OVX test group) or sham operation (SHAM control group). The OVX and SHAM groups were each distributed into three subgroups of ten rats each according to the duration of estrogen deficiency (30, 60 and 90 postoperative days). In all groups, for the last 30 days of the experimental period, cotton ligatures were placed around the cervix of the right upper second molar; the contralateral tooth was left unligated to serve as a control. The maxillary bones were removed, and the alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar. A comparison between the ligated and unligated groups verified the presence of ligature-induced alveolar bone loss (p < 0.05). No significant differences were observed among the unligated groups (p > 0.05). A significant increase in bone loss was observed when ligation occurred 90 days after ovariectomy compared with the sham group (p < 0.05). These results demonstrate that long-term estrogen deficiency affects ligature-induced alveolar bone loss. |
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Influence of different durations of estrogen deficiency on alveolar bone loss in ratsAlveolar Bone LossPeriodontitisBone DiseasesThe purpose of this study was to morphometrically evaluate the influence of different durations of ovariectomy-induced estrogen deficiency on alveolar bone loss associated with ligature-induced bone loss in rats. Sixty female Wistar rats were randomly assigned to ovariectomy (OVX test group) or sham operation (SHAM control group). The OVX and SHAM groups were each distributed into three subgroups of ten rats each according to the duration of estrogen deficiency (30, 60 and 90 postoperative days). In all groups, for the last 30 days of the experimental period, cotton ligatures were placed around the cervix of the right upper second molar; the contralateral tooth was left unligated to serve as a control. The maxillary bones were removed, and the alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar. A comparison between the ligated and unligated groups verified the presence of ligature-induced alveolar bone loss (p < 0.05). No significant differences were observed among the unligated groups (p > 0.05). A significant increase in bone loss was observed when ligation occurred 90 days after ovariectomy compared with the sham group (p < 0.05). These results demonstrate that long-term estrogen deficiency affects ligature-induced alveolar bone loss.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)FAPI Fac Pindamonhangaba, Sch Dent Pindamonhangaba, Dept Dent, Pindamonhangaba, SP, BrazilUNESP Univ Estadual Paulista, Sch Dent Sao Jose dos Campos, Dept Biosci & Oral Diag, Sao Jose Dos Campos, SP, BrazilUNESP Univ Estadual Paulista, Sch Dent Sao Jose dos Campos, Dept Biosci & Oral Diag, Sao Jose Dos Campos, SP, BrazilSociedade Brasileira de Pesquisa Odontológica (SBPqO)FAPI Fac PindamonhangabaUniversidade Estadual Paulista (Unesp)Amadei, Susana UngaroSouza, Daniela Martins deBrandão, Adriana Aigotti Haberbeck [UNESP]da Rocha, Rosilene Fernandes [UNESP]2014-05-20T14:04:36Z2014-05-20T14:04:36Z2011-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article538-543application/pdfhttp://dx.doi.org/10.1590/S1806-83242011000600011Brazilian Oral Research. São Paulo: Sociedade Brasileira de Pesquisa Odontologica, v. 25, n. 6, p. 538-543, 2011.1806-8324http://hdl.handle.net/11449/22667S1806-83242011000600011WOS:000311862200011S1806-83242011000600011.pdf0190365234516027Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Oral Researchinfo:eu-repo/semantics/openAccess2023-12-27T06:23:52Zoai:repositorio.unesp.br:11449/22667Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:27:53.872516Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
spellingShingle |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats Amadei, Susana Ungaro Alveolar Bone Loss Periodontitis Bone Diseases |
title_short |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_full |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_fullStr |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_full_unstemmed |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_sort |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
author |
Amadei, Susana Ungaro |
author_facet |
Amadei, Susana Ungaro Souza, Daniela Martins de Brandão, Adriana Aigotti Haberbeck [UNESP] da Rocha, Rosilene Fernandes [UNESP] |
author_role |
author |
author2 |
Souza, Daniela Martins de Brandão, Adriana Aigotti Haberbeck [UNESP] da Rocha, Rosilene Fernandes [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
FAPI Fac Pindamonhangaba Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Amadei, Susana Ungaro Souza, Daniela Martins de Brandão, Adriana Aigotti Haberbeck [UNESP] da Rocha, Rosilene Fernandes [UNESP] |
dc.subject.por.fl_str_mv |
Alveolar Bone Loss Periodontitis Bone Diseases |
topic |
Alveolar Bone Loss Periodontitis Bone Diseases |
description |
The purpose of this study was to morphometrically evaluate the influence of different durations of ovariectomy-induced estrogen deficiency on alveolar bone loss associated with ligature-induced bone loss in rats. Sixty female Wistar rats were randomly assigned to ovariectomy (OVX test group) or sham operation (SHAM control group). The OVX and SHAM groups were each distributed into three subgroups of ten rats each according to the duration of estrogen deficiency (30, 60 and 90 postoperative days). In all groups, for the last 30 days of the experimental period, cotton ligatures were placed around the cervix of the right upper second molar; the contralateral tooth was left unligated to serve as a control. The maxillary bones were removed, and the alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar. A comparison between the ligated and unligated groups verified the presence of ligature-induced alveolar bone loss (p < 0.05). No significant differences were observed among the unligated groups (p > 0.05). A significant increase in bone loss was observed when ligation occurred 90 days after ovariectomy compared with the sham group (p < 0.05). These results demonstrate that long-term estrogen deficiency affects ligature-induced alveolar bone loss. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-11-01 2014-05-20T14:04:36Z 2014-05-20T14:04:36Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1806-83242011000600011 Brazilian Oral Research. São Paulo: Sociedade Brasileira de Pesquisa Odontologica, v. 25, n. 6, p. 538-543, 2011. 1806-8324 http://hdl.handle.net/11449/22667 S1806-83242011000600011 WOS:000311862200011 S1806-83242011000600011.pdf 0190365234516027 |
url |
http://dx.doi.org/10.1590/S1806-83242011000600011 http://hdl.handle.net/11449/22667 |
identifier_str_mv |
Brazilian Oral Research. São Paulo: Sociedade Brasileira de Pesquisa Odontologica, v. 25, n. 6, p. 538-543, 2011. 1806-8324 S1806-83242011000600011 WOS:000311862200011 S1806-83242011000600011.pdf 0190365234516027 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Oral Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
538-543 application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129323501092864 |