A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/245329 |
Resumo: | Polycyclic aromatic hydrocarbons (PAHs) are one of the most important, abundant and dangerous class of persistent organic contaminants found in air, water, food and waste sites. The great concern with this class of pollutants is due to the fact that these chemicals cause various deleterious effects, which could jeopardize the genome of exposed organisms or even lead them to death. Many studies have been conducted in several laboratories distributed around the world and with different organisms to quantify the impact of those pollutants and to diagnose their action mechanisms. Thus, there is a real necessity to compile the data already described in the literature, obtained from tests in situ, in vivo and in vitro, derived from simulation experiments, occupational exposure or environmental disasters, in order to produce a report with the main effects already described for that class of pollutant. This review article intends to address the following issues: toxicity, cytotoxicity, genotoxicity, mutagenicity, teratogenicity and carcinogenicity of PAHs, besides information about estrogenicity and metabolism of these substances. In this context, it will be also presented the test systems that better responded to the assessments of the PAHs effects, in an attempt to show the most sensitive and efficient organisms to detect the contamination of these agents. |
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spelling |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMSPolycyclic aromatic hydrocarbons (PAHs) are one of the most important, abundant and dangerous class of persistent organic contaminants found in air, water, food and waste sites. The great concern with this class of pollutants is due to the fact that these chemicals cause various deleterious effects, which could jeopardize the genome of exposed organisms or even lead them to death. Many studies have been conducted in several laboratories distributed around the world and with different organisms to quantify the impact of those pollutants and to diagnose their action mechanisms. Thus, there is a real necessity to compile the data already described in the literature, obtained from tests in situ, in vivo and in vitro, derived from simulation experiments, occupational exposure or environmental disasters, in order to produce a report with the main effects already described for that class of pollutant. This review article intends to address the following issues: toxicity, cytotoxicity, genotoxicity, mutagenicity, teratogenicity and carcinogenicity of PAHs, besides information about estrogenicity and metabolism of these substances. In this context, it will be also presented the test systems that better responded to the assessments of the PAHs effects, in an attempt to show the most sensitive and efficient organisms to detect the contamination of these agents.Sao Paulo State Univ, Inst Biosci, Dept Biol, Rio Claro, SP, BrazilUNESP MCT FINEP ANP, Setor Petr Gas & Biocombust PRHO5, Programa Formacao Recursos Humanos Geol & Ciencia, Sao Paulo, BrazilFAPESP, Sao Paulo, BrazilSao Paulo State Univ, Inst Biosci, Dept Biol, Rio Claro, SP, BrazilUNESP MCT FINEP ANP, Setor Petr Gas & Biocombust PRHO5, Programa Formacao Recursos Humanos Geol & Ciencia, Sao Paulo, BrazilNova Science Publishers, IncUniversidade Estadual Paulista (UNESP)FAPESPMarin-Morales, Maria Aparecida [UNESP]Leme, Daniela Morais [UNESP]Christofoletti Mazzeo, Dania Elisa [UNESP]Haines, P. A.Hendrickson, M. D.2023-07-29T11:51:40Z2023-07-29T11:51:40Z2009-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-49Polycyclic Aromatic Hydrocarbons: Pollution, Health Effects and Chemistry. Hauppauge: Nova Science Publishers, Inc, p. 1-49, 2009.http://hdl.handle.net/11449/245329WOS:000278688900001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPolycyclic Aromatic Hydrocarbons: Pollution, Health Effects And Chemistryinfo:eu-repo/semantics/openAccess2023-07-29T11:51:40Zoai:repositorio.unesp.br:11449/245329Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-07-29T11:51:40Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS |
title |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS |
spellingShingle |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS Marin-Morales, Maria Aparecida [UNESP] |
title_short |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS |
title_full |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS |
title_fullStr |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS |
title_full_unstemmed |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS |
title_sort |
A REVIEW OF THE HAZARDOUS EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON LIVING ORGANISMS |
author |
Marin-Morales, Maria Aparecida [UNESP] |
author_facet |
Marin-Morales, Maria Aparecida [UNESP] Leme, Daniela Morais [UNESP] Christofoletti Mazzeo, Dania Elisa [UNESP] Haines, P. A. Hendrickson, M. D. |
author_role |
author |
author2 |
Leme, Daniela Morais [UNESP] Christofoletti Mazzeo, Dania Elisa [UNESP] Haines, P. A. Hendrickson, M. D. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) FAPESP |
dc.contributor.author.fl_str_mv |
Marin-Morales, Maria Aparecida [UNESP] Leme, Daniela Morais [UNESP] Christofoletti Mazzeo, Dania Elisa [UNESP] Haines, P. A. Hendrickson, M. D. |
description |
Polycyclic aromatic hydrocarbons (PAHs) are one of the most important, abundant and dangerous class of persistent organic contaminants found in air, water, food and waste sites. The great concern with this class of pollutants is due to the fact that these chemicals cause various deleterious effects, which could jeopardize the genome of exposed organisms or even lead them to death. Many studies have been conducted in several laboratories distributed around the world and with different organisms to quantify the impact of those pollutants and to diagnose their action mechanisms. Thus, there is a real necessity to compile the data already described in the literature, obtained from tests in situ, in vivo and in vitro, derived from simulation experiments, occupational exposure or environmental disasters, in order to produce a report with the main effects already described for that class of pollutant. This review article intends to address the following issues: toxicity, cytotoxicity, genotoxicity, mutagenicity, teratogenicity and carcinogenicity of PAHs, besides information about estrogenicity and metabolism of these substances. In this context, it will be also presented the test systems that better responded to the assessments of the PAHs effects, in an attempt to show the most sensitive and efficient organisms to detect the contamination of these agents. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 2023-07-29T11:51:40Z 2023-07-29T11:51:40Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Polycyclic Aromatic Hydrocarbons: Pollution, Health Effects and Chemistry. Hauppauge: Nova Science Publishers, Inc, p. 1-49, 2009. http://hdl.handle.net/11449/245329 WOS:000278688900001 |
identifier_str_mv |
Polycyclic Aromatic Hydrocarbons: Pollution, Health Effects and Chemistry. Hauppauge: Nova Science Publishers, Inc, p. 1-49, 2009. WOS:000278688900001 |
url |
http://hdl.handle.net/11449/245329 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Polycyclic Aromatic Hydrocarbons: Pollution, Health Effects And Chemistry |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-49 |
dc.publisher.none.fl_str_mv |
Nova Science Publishers, Inc |
publisher.none.fl_str_mv |
Nova Science Publishers, Inc |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964911648899072 |