The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNESP |
| Texto Completo: | http://dx.doi.org/10.1590/S1516-89132011000600016 http://hdl.handle.net/11449/8183 |
Resumo: | The aim of the present study was to examine the effect of a diet rich in synthetic PEtn on the metabolism macrophages of tumor-bearing mice. The results demonstrated that PEtn increased the animals' survival time. In addition, the treated animals released smaller amounts of hydrogen peroxide (H2O2) and nitric oxide (NO) than the non-treated animals, particularly after day 14. From the results it could be concluded that H2O2 and NO were important in the modulation of neoplastic growth, and pointed to a promising role of PEtn in the control of human neoplasms. |
| id |
UNSP_51de894b93b2cf87f97ed3856d4c327a |
|---|---|
| oai_identifier_str |
oai:repositorio.unesp.br:11449/8183 |
| network_acronym_str |
UNSP |
| network_name_str |
Repositório Institucional da UNESP |
| repository_id_str |
2946 |
| spelling |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumorsPhosphoethanolamineEhrlich tumornitric oxidehydrogen peroxidelipidsThe aim of the present study was to examine the effect of a diet rich in synthetic PEtn on the metabolism macrophages of tumor-bearing mice. The results demonstrated that PEtn increased the animals' survival time. In addition, the treated animals released smaller amounts of hydrogen peroxide (H2O2) and nitric oxide (NO) than the non-treated animals, particularly after day 14. From the results it could be concluded that H2O2 and NO were important in the modulation of neoplastic growth, and pointed to a promising role of PEtn in the control of human neoplasms.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação para o Desenvolvimento da UNESP (FUNDUNESP)Universidade Estadual Paulista Faculdade de Ciências Departamento de Ciências BiológicasUniversidade Estadual Paulista Faculdade de Ciências Departamento de QuímicaUniversidade de São Paulo Departamento de Química e Física MolecularInsituto Lauro de Sousa LimaUniversidade Estadual Paulista Faculdade de Ciências Departamento de Ciências BiológicasUniversidade Estadual Paulista Faculdade de Ciências Departamento de QuímicaBrazilian Archives of Biology and TechnologyUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Insituto Lauro de Sousa LimaArruda, Maria Sueli Parreira de [UNESP]Correa, Mara Adriana [UNESP]Venturini, James [UNESP]Félix, Maira Camila [UNESP]De Rosis, Ana Maria Bormio [UNESP]Galhiane, Mario Sergio [UNESP]Chierice, Gilberto OrivaldoCosta, Maria Renata Sales Nogueira2014-05-20T13:25:44Z2014-05-20T13:25:44Z2011-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1203-1210application/pdfhttp://dx.doi.org/10.1590/S1516-89132011000600016Brazilian Archives of Biology and Technology. Brazilian Archives of Biology and Technology, v. 54, n. 6, p. 1203-1210, 2011.1516-8913http://hdl.handle.net/11449/818310.1590/S1516-89132011000600016S1516-89132011000600016WOS:000298106300016S1516-89132011000600016.pdf07114315665030223612277056838097SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Archives of Biology and Technology0.6760,281info:eu-repo/semantics/openAccess2024-04-29T18:17:11Zoai:repositorio.unesp.br:11449/8183Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:50:25.444290Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
| dc.title.none.fl_str_mv |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors |
| title |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors |
| spellingShingle |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors Arruda, Maria Sueli Parreira de [UNESP] Phosphoethanolamine Ehrlich tumor nitric oxide hydrogen peroxide lipids |
| title_short |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors |
| title_full |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors |
| title_fullStr |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors |
| title_full_unstemmed |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors |
| title_sort |
The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors |
| author |
Arruda, Maria Sueli Parreira de [UNESP] |
| author_facet |
Arruda, Maria Sueli Parreira de [UNESP] Correa, Mara Adriana [UNESP] Venturini, James [UNESP] Félix, Maira Camila [UNESP] De Rosis, Ana Maria Bormio [UNESP] Galhiane, Mario Sergio [UNESP] Chierice, Gilberto Orivaldo Costa, Maria Renata Sales Nogueira |
| author_role |
author |
| author2 |
Correa, Mara Adriana [UNESP] Venturini, James [UNESP] Félix, Maira Camila [UNESP] De Rosis, Ana Maria Bormio [UNESP] Galhiane, Mario Sergio [UNESP] Chierice, Gilberto Orivaldo Costa, Maria Renata Sales Nogueira |
| author2_role |
author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) Insituto Lauro de Sousa Lima |
| dc.contributor.author.fl_str_mv |
Arruda, Maria Sueli Parreira de [UNESP] Correa, Mara Adriana [UNESP] Venturini, James [UNESP] Félix, Maira Camila [UNESP] De Rosis, Ana Maria Bormio [UNESP] Galhiane, Mario Sergio [UNESP] Chierice, Gilberto Orivaldo Costa, Maria Renata Sales Nogueira |
| dc.subject.por.fl_str_mv |
Phosphoethanolamine Ehrlich tumor nitric oxide hydrogen peroxide lipids |
| topic |
Phosphoethanolamine Ehrlich tumor nitric oxide hydrogen peroxide lipids |
| description |
The aim of the present study was to examine the effect of a diet rich in synthetic PEtn on the metabolism macrophages of tumor-bearing mice. The results demonstrated that PEtn increased the animals' survival time. In addition, the treated animals released smaller amounts of hydrogen peroxide (H2O2) and nitric oxide (NO) than the non-treated animals, particularly after day 14. From the results it could be concluded that H2O2 and NO were important in the modulation of neoplastic growth, and pointed to a promising role of PEtn in the control of human neoplasms. |
| publishDate |
2011 |
| dc.date.none.fl_str_mv |
2011-12-01 2014-05-20T13:25:44Z 2014-05-20T13:25:44Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1516-89132011000600016 Brazilian Archives of Biology and Technology. Brazilian Archives of Biology and Technology, v. 54, n. 6, p. 1203-1210, 2011. 1516-8913 http://hdl.handle.net/11449/8183 10.1590/S1516-89132011000600016 S1516-89132011000600016 WOS:000298106300016 S1516-89132011000600016.pdf 0711431566503022 3612277056838097 |
| url |
http://dx.doi.org/10.1590/S1516-89132011000600016 http://hdl.handle.net/11449/8183 |
| identifier_str_mv |
Brazilian Archives of Biology and Technology. Brazilian Archives of Biology and Technology, v. 54, n. 6, p. 1203-1210, 2011. 1516-8913 10.1590/S1516-89132011000600016 S1516-89132011000600016 WOS:000298106300016 S1516-89132011000600016.pdf 0711431566503022 3612277056838097 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Brazilian Archives of Biology and Technology 0.676 0,281 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
1203-1210 application/pdf |
| dc.publisher.none.fl_str_mv |
Brazilian Archives of Biology and Technology |
| publisher.none.fl_str_mv |
Brazilian Archives of Biology and Technology |
| dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
| instname_str |
Universidade Estadual Paulista (UNESP) |
| instacron_str |
UNESP |
| institution |
UNESP |
| reponame_str |
Repositório Institucional da UNESP |
| collection |
Repositório Institucional da UNESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
| repository.mail.fl_str_mv |
|
| _version_ |
1808129126482051072 |