Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil

Detalhes bibliográficos
Autor(a) principal: Demoner, Larissa de Castro [UNESP]
Data de Publicação: 2016
Outros Autores: Magro, Natalia Mizuhira [UNESP], da Silva, Maria Regina Lucas [UNESP], de Paula Antunes, João Marcelo Azevedo, Calabuig, Cecilia Irene Pérez, O'Dwyer, Lucia Helena [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.ttbdis.2016.04.002
http://hdl.handle.net/11449/172820
Resumo: Hepatozoon canis is a tick-borne parasite that occurs worldwide. In rural areas of Brazil, H. canis vectors remain unknown, which has led to speculation about alternative routes of transmission. Small rodents can play a role in the transmission (via predation) of Hepatozoon americanum, which led us to question whether predation might be an alternative mode of transmission for H. canis. Thus, this study investigated whether Hepatozoon spp. are present in wild small rodents in forest fragments that surround rural areas in Botucatu County, São Paulo, Brazil, where canine hepatozoonosis is endemic. The study included blood samples from 158 dogs, which were screened by microscopy and molecular analysis. Blood samples and tissues from 67 rodents were obtained for histopathology and molecular detection. The prevalence of H. canis was high (66.45%) in dogs from rural areas of Botucatu, São Paulo, Brazil. The molecular analysis showed that wild rodent species in Brazil were infected with Hepatozoon spp. other than H. canis. Therefore, although the hypothesis that sylvatic rodents act as reservoirs for H. canis was not supported, the presence of monozoic cysts in the rodents suggests that, in addition to intermediate hosts, wild small rodents in Brazil might act as paratenic hosts of Hepatozoon spp. because they harbor infective stages for intermediate host predators.
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spelling Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern BrazilDogsHepatozoon canisParatenic hostsTransmissionWild rodentsHepatozoon canis is a tick-borne parasite that occurs worldwide. In rural areas of Brazil, H. canis vectors remain unknown, which has led to speculation about alternative routes of transmission. Small rodents can play a role in the transmission (via predation) of Hepatozoon americanum, which led us to question whether predation might be an alternative mode of transmission for H. canis. Thus, this study investigated whether Hepatozoon spp. are present in wild small rodents in forest fragments that surround rural areas in Botucatu County, São Paulo, Brazil, where canine hepatozoonosis is endemic. The study included blood samples from 158 dogs, which were screened by microscopy and molecular analysis. Blood samples and tissues from 67 rodents were obtained for histopathology and molecular detection. The prevalence of H. canis was high (66.45%) in dogs from rural areas of Botucatu, São Paulo, Brazil. The molecular analysis showed that wild rodent species in Brazil were infected with Hepatozoon spp. other than H. canis. Therefore, although the hypothesis that sylvatic rodents act as reservoirs for H. canis was not supported, the presence of monozoic cysts in the rodents suggests that, in addition to intermediate hosts, wild small rodents in Brazil might act as paratenic hosts of Hepatozoon spp. because they harbor infective stages for intermediate host predators.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Instituto de Biociências UNESP-Univ Estadual Paulista Campus de Botucatu Departamento de Parasitologia, Distrito de Rubião JuniorDepartamento de Ciências Animais Universidade Federal Rural do Semiárido, Av. Francisco Mota 572Instituto de Biociências UNESP-Univ Estadual Paulista Campus de Botucatu Departamento de Parasitologia, Distrito de Rubião JuniorUniversidade Estadual Paulista (Unesp)Universidade Federal Rural do SemiáridoDemoner, Larissa de Castro [UNESP]Magro, Natalia Mizuhira [UNESP]da Silva, Maria Regina Lucas [UNESP]de Paula Antunes, João Marcelo AzevedoCalabuig, Cecilia Irene PérezO'Dwyer, Lucia Helena [UNESP]2018-12-11T17:02:18Z2018-12-11T17:02:18Z2016-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article859-864application/pdfhttp://dx.doi.org/10.1016/j.ttbdis.2016.04.002Ticks and Tick-borne Diseases, v. 7, n. 5, p. 859-864, 2016.1877-96031877-959Xhttp://hdl.handle.net/11449/17282010.1016/j.ttbdis.2016.04.0022-s2.0-849636540412-s2.0-84963654041.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTicks and Tick-borne Diseases1,421info:eu-repo/semantics/openAccess2023-11-04T06:10:47Zoai:repositorio.unesp.br:11449/172820Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:53:56.692238Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
title Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
spellingShingle Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
Demoner, Larissa de Castro [UNESP]
Dogs
Hepatozoon canis
Paratenic hosts
Transmission
Wild rodents
title_short Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
title_full Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
title_fullStr Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
title_full_unstemmed Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
title_sort Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
author Demoner, Larissa de Castro [UNESP]
author_facet Demoner, Larissa de Castro [UNESP]
Magro, Natalia Mizuhira [UNESP]
da Silva, Maria Regina Lucas [UNESP]
de Paula Antunes, João Marcelo Azevedo
Calabuig, Cecilia Irene Pérez
O'Dwyer, Lucia Helena [UNESP]
author_role author
author2 Magro, Natalia Mizuhira [UNESP]
da Silva, Maria Regina Lucas [UNESP]
de Paula Antunes, João Marcelo Azevedo
Calabuig, Cecilia Irene Pérez
O'Dwyer, Lucia Helena [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal Rural do Semiárido
dc.contributor.author.fl_str_mv Demoner, Larissa de Castro [UNESP]
Magro, Natalia Mizuhira [UNESP]
da Silva, Maria Regina Lucas [UNESP]
de Paula Antunes, João Marcelo Azevedo
Calabuig, Cecilia Irene Pérez
O'Dwyer, Lucia Helena [UNESP]
dc.subject.por.fl_str_mv Dogs
Hepatozoon canis
Paratenic hosts
Transmission
Wild rodents
topic Dogs
Hepatozoon canis
Paratenic hosts
Transmission
Wild rodents
description Hepatozoon canis is a tick-borne parasite that occurs worldwide. In rural areas of Brazil, H. canis vectors remain unknown, which has led to speculation about alternative routes of transmission. Small rodents can play a role in the transmission (via predation) of Hepatozoon americanum, which led us to question whether predation might be an alternative mode of transmission for H. canis. Thus, this study investigated whether Hepatozoon spp. are present in wild small rodents in forest fragments that surround rural areas in Botucatu County, São Paulo, Brazil, where canine hepatozoonosis is endemic. The study included blood samples from 158 dogs, which were screened by microscopy and molecular analysis. Blood samples and tissues from 67 rodents were obtained for histopathology and molecular detection. The prevalence of H. canis was high (66.45%) in dogs from rural areas of Botucatu, São Paulo, Brazil. The molecular analysis showed that wild rodent species in Brazil were infected with Hepatozoon spp. other than H. canis. Therefore, although the hypothesis that sylvatic rodents act as reservoirs for H. canis was not supported, the presence of monozoic cysts in the rodents suggests that, in addition to intermediate hosts, wild small rodents in Brazil might act as paratenic hosts of Hepatozoon spp. because they harbor infective stages for intermediate host predators.
publishDate 2016
dc.date.none.fl_str_mv 2016-07-01
2018-12-11T17:02:18Z
2018-12-11T17:02:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.ttbdis.2016.04.002
Ticks and Tick-borne Diseases, v. 7, n. 5, p. 859-864, 2016.
1877-9603
1877-959X
http://hdl.handle.net/11449/172820
10.1016/j.ttbdis.2016.04.002
2-s2.0-84963654041
2-s2.0-84963654041.pdf
url http://dx.doi.org/10.1016/j.ttbdis.2016.04.002
http://hdl.handle.net/11449/172820
identifier_str_mv Ticks and Tick-borne Diseases, v. 7, n. 5, p. 859-864, 2016.
1877-9603
1877-959X
10.1016/j.ttbdis.2016.04.002
2-s2.0-84963654041
2-s2.0-84963654041.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ticks and Tick-borne Diseases
1,421
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 859-864
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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