Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.ttbdis.2016.04.002 http://hdl.handle.net/11449/172820 |
Resumo: | Hepatozoon canis is a tick-borne parasite that occurs worldwide. In rural areas of Brazil, H. canis vectors remain unknown, which has led to speculation about alternative routes of transmission. Small rodents can play a role in the transmission (via predation) of Hepatozoon americanum, which led us to question whether predation might be an alternative mode of transmission for H. canis. Thus, this study investigated whether Hepatozoon spp. are present in wild small rodents in forest fragments that surround rural areas in Botucatu County, São Paulo, Brazil, where canine hepatozoonosis is endemic. The study included blood samples from 158 dogs, which were screened by microscopy and molecular analysis. Blood samples and tissues from 67 rodents were obtained for histopathology and molecular detection. The prevalence of H. canis was high (66.45%) in dogs from rural areas of Botucatu, São Paulo, Brazil. The molecular analysis showed that wild rodent species in Brazil were infected with Hepatozoon spp. other than H. canis. Therefore, although the hypothesis that sylvatic rodents act as reservoirs for H. canis was not supported, the presence of monozoic cysts in the rodents suggests that, in addition to intermediate hosts, wild small rodents in Brazil might act as paratenic hosts of Hepatozoon spp. because they harbor infective stages for intermediate host predators. |
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Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern BrazilDogsHepatozoon canisParatenic hostsTransmissionWild rodentsHepatozoon canis is a tick-borne parasite that occurs worldwide. In rural areas of Brazil, H. canis vectors remain unknown, which has led to speculation about alternative routes of transmission. Small rodents can play a role in the transmission (via predation) of Hepatozoon americanum, which led us to question whether predation might be an alternative mode of transmission for H. canis. Thus, this study investigated whether Hepatozoon spp. are present in wild small rodents in forest fragments that surround rural areas in Botucatu County, São Paulo, Brazil, where canine hepatozoonosis is endemic. The study included blood samples from 158 dogs, which were screened by microscopy and molecular analysis. Blood samples and tissues from 67 rodents were obtained for histopathology and molecular detection. The prevalence of H. canis was high (66.45%) in dogs from rural areas of Botucatu, São Paulo, Brazil. The molecular analysis showed that wild rodent species in Brazil were infected with Hepatozoon spp. other than H. canis. Therefore, although the hypothesis that sylvatic rodents act as reservoirs for H. canis was not supported, the presence of monozoic cysts in the rodents suggests that, in addition to intermediate hosts, wild small rodents in Brazil might act as paratenic hosts of Hepatozoon spp. because they harbor infective stages for intermediate host predators.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Instituto de Biociências UNESP-Univ Estadual Paulista Campus de Botucatu Departamento de Parasitologia, Distrito de Rubião JuniorDepartamento de Ciências Animais Universidade Federal Rural do Semiárido, Av. Francisco Mota 572Instituto de Biociências UNESP-Univ Estadual Paulista Campus de Botucatu Departamento de Parasitologia, Distrito de Rubião JuniorUniversidade Estadual Paulista (Unesp)Universidade Federal Rural do SemiáridoDemoner, Larissa de Castro [UNESP]Magro, Natalia Mizuhira [UNESP]da Silva, Maria Regina Lucas [UNESP]de Paula Antunes, João Marcelo AzevedoCalabuig, Cecilia Irene PérezO'Dwyer, Lucia Helena [UNESP]2018-12-11T17:02:18Z2018-12-11T17:02:18Z2016-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article859-864application/pdfhttp://dx.doi.org/10.1016/j.ttbdis.2016.04.002Ticks and Tick-borne Diseases, v. 7, n. 5, p. 859-864, 2016.1877-96031877-959Xhttp://hdl.handle.net/11449/17282010.1016/j.ttbdis.2016.04.0022-s2.0-849636540412-s2.0-84963654041.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTicks and Tick-borne Diseases1,421info:eu-repo/semantics/openAccess2023-11-04T06:10:47Zoai:repositorio.unesp.br:11449/172820Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:53:56.692238Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil |
title |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil |
spellingShingle |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil Demoner, Larissa de Castro [UNESP] Dogs Hepatozoon canis Paratenic hosts Transmission Wild rodents |
title_short |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil |
title_full |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil |
title_fullStr |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil |
title_full_unstemmed |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil |
title_sort |
Hepatozoon spp. infections in wild rodents in an area of endemic canine hepatozoonosis in southeastern Brazil |
author |
Demoner, Larissa de Castro [UNESP] |
author_facet |
Demoner, Larissa de Castro [UNESP] Magro, Natalia Mizuhira [UNESP] da Silva, Maria Regina Lucas [UNESP] de Paula Antunes, João Marcelo Azevedo Calabuig, Cecilia Irene Pérez O'Dwyer, Lucia Helena [UNESP] |
author_role |
author |
author2 |
Magro, Natalia Mizuhira [UNESP] da Silva, Maria Regina Lucas [UNESP] de Paula Antunes, João Marcelo Azevedo Calabuig, Cecilia Irene Pérez O'Dwyer, Lucia Helena [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal Rural do Semiárido |
dc.contributor.author.fl_str_mv |
Demoner, Larissa de Castro [UNESP] Magro, Natalia Mizuhira [UNESP] da Silva, Maria Regina Lucas [UNESP] de Paula Antunes, João Marcelo Azevedo Calabuig, Cecilia Irene Pérez O'Dwyer, Lucia Helena [UNESP] |
dc.subject.por.fl_str_mv |
Dogs Hepatozoon canis Paratenic hosts Transmission Wild rodents |
topic |
Dogs Hepatozoon canis Paratenic hosts Transmission Wild rodents |
description |
Hepatozoon canis is a tick-borne parasite that occurs worldwide. In rural areas of Brazil, H. canis vectors remain unknown, which has led to speculation about alternative routes of transmission. Small rodents can play a role in the transmission (via predation) of Hepatozoon americanum, which led us to question whether predation might be an alternative mode of transmission for H. canis. Thus, this study investigated whether Hepatozoon spp. are present in wild small rodents in forest fragments that surround rural areas in Botucatu County, São Paulo, Brazil, where canine hepatozoonosis is endemic. The study included blood samples from 158 dogs, which were screened by microscopy and molecular analysis. Blood samples and tissues from 67 rodents were obtained for histopathology and molecular detection. The prevalence of H. canis was high (66.45%) in dogs from rural areas of Botucatu, São Paulo, Brazil. The molecular analysis showed that wild rodent species in Brazil were infected with Hepatozoon spp. other than H. canis. Therefore, although the hypothesis that sylvatic rodents act as reservoirs for H. canis was not supported, the presence of monozoic cysts in the rodents suggests that, in addition to intermediate hosts, wild small rodents in Brazil might act as paratenic hosts of Hepatozoon spp. because they harbor infective stages for intermediate host predators. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-07-01 2018-12-11T17:02:18Z 2018-12-11T17:02:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.ttbdis.2016.04.002 Ticks and Tick-borne Diseases, v. 7, n. 5, p. 859-864, 2016. 1877-9603 1877-959X http://hdl.handle.net/11449/172820 10.1016/j.ttbdis.2016.04.002 2-s2.0-84963654041 2-s2.0-84963654041.pdf |
url |
http://dx.doi.org/10.1016/j.ttbdis.2016.04.002 http://hdl.handle.net/11449/172820 |
identifier_str_mv |
Ticks and Tick-borne Diseases, v. 7, n. 5, p. 859-864, 2016. 1877-9603 1877-959X 10.1016/j.ttbdis.2016.04.002 2-s2.0-84963654041 2-s2.0-84963654041.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ticks and Tick-borne Diseases 1,421 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
859-864 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128718616395776 |