Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft

Detalhes bibliográficos
Autor(a) principal: Rahal, S.c. [UNESP]
Data de Publicação: 2004
Outros Autores: Amaral, M.s.p., Pai, V.d., Barraviera, S.r.c.s. [UNESP], Caporal, E.h.g, Crocci, A.j. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-91992004000200006
http://hdl.handle.net/11449/213101
Resumo: The aim of this study was to analyze the effect of snake venom derived from fibrin glue on the viability of split-thickness skin graft. Nine crossbreed dogs were used. Full-thickness skin segments measuring 4 x 4 cm were bilaterally excised from the proximal radial area on each dog. A split-thickness skin graft was harvestedfrom left lateral thoracic area using a freehand graft knife, and was secured to the left recipient bed using several simple interrupted sutures of 3-0 nylon (sutured graft). A split-thickness skin graft was harvested from the right lateral thoracic area using a graft knife. Fibrin glue derived from snake venom was applied to the recipient bed, and 8 equidistant simple interrupted sutures of 3-0 nylon were used to secure the skin graft (glued graft). Viable and nonviable areas were traced on a transparent sheet and measured using a Nikon Photomicroscope connected to a KS-300 image analysis system. The skin graft and recipient bed were collected from three dogs at day 7, 15, and 30 postoperative. The glued grafts had statistically higher graft viability than sutured grafts. Histological examination showed that the tissue repair process in the glued grafts was more accentuated than sutured grafts. It was possible to conclude that fibrin glue derived from snake venom increased survival of autogenous split-thickness skin graft.
id UNSP_52ac94b0ed76469b1ea6429b5fb1c4b3
oai_identifier_str oai:repositorio.unesp.br:11449/213101
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graftfibrin glueskin graftsnake venomdogsThe aim of this study was to analyze the effect of snake venom derived from fibrin glue on the viability of split-thickness skin graft. Nine crossbreed dogs were used. Full-thickness skin segments measuring 4 x 4 cm were bilaterally excised from the proximal radial area on each dog. A split-thickness skin graft was harvestedfrom left lateral thoracic area using a freehand graft knife, and was secured to the left recipient bed using several simple interrupted sutures of 3-0 nylon (sutured graft). A split-thickness skin graft was harvested from the right lateral thoracic area using a graft knife. Fibrin glue derived from snake venom was applied to the recipient bed, and 8 equidistant simple interrupted sutures of 3-0 nylon were used to secure the skin graft (glued graft). Viable and nonviable areas were traced on a transparent sheet and measured using a Nikon Photomicroscope connected to a KS-300 image analysis system. The skin graft and recipient bed were collected from three dogs at day 7, 15, and 30 postoperative. The glued grafts had statistically higher graft viability than sutured grafts. Histological examination showed that the tissue repair process in the glued grafts was more accentuated than sutured grafts. It was possible to conclude that fibrin glue derived from snake venom increased survival of autogenous split-thickness skin graft.Universidade Estadual Paulista, Faculty of Veterinary Medicine and Animal ScienceUniversidade Estadual Paulista, Faculty of MedicineUniversidade do Oeste Paulista, Faculty of Agrarian ScienceUniversidade Estadual Paulista, Bioscience InstituteUniversidade Estadual Paulista, Faculty of Veterinary Medicine and Animal ScienceUniversidade Estadual Paulista, Faculty of MedicineUniversidade Estadual Paulista, Bioscience InstituteCentro de Estudos de Venenos e Animais PeçonhentosUniversidade Estadual Paulista (Unesp)Universidade do Oeste PaulistaRahal, S.c. [UNESP]Amaral, M.s.p.Pai, V.d.Barraviera, S.r.c.s. [UNESP]Caporal, E.h.gCrocci, A.j. [UNESP]2021-07-14T10:50:00Z2021-07-14T10:50:00Z2004info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article161-172application/pdfhttp://dx.doi.org/10.1590/S1678-91992004000200006Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 10, n. 2, p. 161-172, 2004.1678-9199http://hdl.handle.net/11449/21310110.1590/S1678-91992004000200006S1678-91992004000200006S1678-91992004000200006.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins including Tropical Diseasesinfo:eu-repo/semantics/openAccess2023-12-30T06:16:22Zoai:repositorio.unesp.br:11449/213101Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:40:34.351091Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
title Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
spellingShingle Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
Rahal, S.c. [UNESP]
fibrin glue
skin graft
snake venom
dogs
title_short Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
title_full Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
title_fullStr Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
title_full_unstemmed Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
title_sort Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
author Rahal, S.c. [UNESP]
author_facet Rahal, S.c. [UNESP]
Amaral, M.s.p.
Pai, V.d.
Barraviera, S.r.c.s. [UNESP]
Caporal, E.h.g
Crocci, A.j. [UNESP]
author_role author
author2 Amaral, M.s.p.
Pai, V.d.
Barraviera, S.r.c.s. [UNESP]
Caporal, E.h.g
Crocci, A.j. [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade do Oeste Paulista
dc.contributor.author.fl_str_mv Rahal, S.c. [UNESP]
Amaral, M.s.p.
Pai, V.d.
Barraviera, S.r.c.s. [UNESP]
Caporal, E.h.g
Crocci, A.j. [UNESP]
dc.subject.por.fl_str_mv fibrin glue
skin graft
snake venom
dogs
topic fibrin glue
skin graft
snake venom
dogs
description The aim of this study was to analyze the effect of snake venom derived from fibrin glue on the viability of split-thickness skin graft. Nine crossbreed dogs were used. Full-thickness skin segments measuring 4 x 4 cm were bilaterally excised from the proximal radial area on each dog. A split-thickness skin graft was harvestedfrom left lateral thoracic area using a freehand graft knife, and was secured to the left recipient bed using several simple interrupted sutures of 3-0 nylon (sutured graft). A split-thickness skin graft was harvested from the right lateral thoracic area using a graft knife. Fibrin glue derived from snake venom was applied to the recipient bed, and 8 equidistant simple interrupted sutures of 3-0 nylon were used to secure the skin graft (glued graft). Viable and nonviable areas were traced on a transparent sheet and measured using a Nikon Photomicroscope connected to a KS-300 image analysis system. The skin graft and recipient bed were collected from three dogs at day 7, 15, and 30 postoperative. The glued grafts had statistically higher graft viability than sutured grafts. Histological examination showed that the tissue repair process in the glued grafts was more accentuated than sutured grafts. It was possible to conclude that fibrin glue derived from snake venom increased survival of autogenous split-thickness skin graft.
publishDate 2004
dc.date.none.fl_str_mv 2004
2021-07-14T10:50:00Z
2021-07-14T10:50:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-91992004000200006
Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 10, n. 2, p. 161-172, 2004.
1678-9199
http://hdl.handle.net/11449/213101
10.1590/S1678-91992004000200006
S1678-91992004000200006
S1678-91992004000200006.pdf
url http://dx.doi.org/10.1590/S1678-91992004000200006
http://hdl.handle.net/11449/213101
identifier_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 10, n. 2, p. 161-172, 2004.
1678-9199
10.1590/S1678-91992004000200006
S1678-91992004000200006
S1678-91992004000200006.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 161-172
application/pdf
dc.publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos
publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129345499168768