Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?

Detalhes bibliográficos
Autor(a) principal: Valli, Marilia [UNESP]
Data de Publicação: 2012
Outros Autores: Pivatto, Marcos [UNESP], Danuello, Amanda [UNESP], Castro-Gamboa, Ian [UNESP], Silva, Dulce Helena Siqueira [UNESP], Cavalheiro, Alberto José [UNESP], Araújo, Angela Regina [UNESP], Furlan, Maysa [UNESP], Lopes, Márcia Nasser [UNESP], Bolzani, Vanderlan da Silva [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0100-40422012001100036
http://hdl.handle.net/11449/26395
Resumo: The use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery.
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spelling Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?natural productsmedicinal chemistrytropical biodiversityThe use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual Paulista Júlio de Mesquita Filho Instituto de Química Departamento de Química OrgânicaUniversidade Estadual Paulista Júlio de Mesquita Filho Instituto de Química Departamento de Química OrgânicaSociedade Brasileira de QuímicaUniversidade Estadual Paulista (Unesp)Valli, Marilia [UNESP]Pivatto, Marcos [UNESP]Danuello, Amanda [UNESP]Castro-Gamboa, Ian [UNESP]Silva, Dulce Helena Siqueira [UNESP]Cavalheiro, Alberto José [UNESP]Araújo, Angela Regina [UNESP]Furlan, Maysa [UNESP]Lopes, Márcia Nasser [UNESP]Bolzani, Vanderlan da Silva [UNESP]2014-05-20T14:21:25Z2014-05-20T14:21:25Z2012-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2278-2287application/pdfhttp://dx.doi.org/10.1590/S0100-40422012001100036Química Nova. Sociedade Brasileira de Química, v. 35, n. 11, p. 2278-2287, 2012.0100-4042http://hdl.handle.net/11449/2639510.1590/S0100-40422012001100036S0100-40422012001100036WOS:000312034600036S0100-40422012001100036.pdf4702004904231248251800682076412000375790540831601308042794786872331017089969394444840836852516730000-0001-7616-96520000-0002-1516-7765SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengQuímica Nova0.6460,255info:eu-repo/semantics/openAccess2023-10-24T06:06:40Zoai:repositorio.unesp.br:11449/26395Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-24T06:06:40Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
title Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
spellingShingle Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
Valli, Marilia [UNESP]
natural products
medicinal chemistry
tropical biodiversity
title_short Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
title_full Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
title_fullStr Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
title_full_unstemmed Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
title_sort Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
author Valli, Marilia [UNESP]
author_facet Valli, Marilia [UNESP]
Pivatto, Marcos [UNESP]
Danuello, Amanda [UNESP]
Castro-Gamboa, Ian [UNESP]
Silva, Dulce Helena Siqueira [UNESP]
Cavalheiro, Alberto José [UNESP]
Araújo, Angela Regina [UNESP]
Furlan, Maysa [UNESP]
Lopes, Márcia Nasser [UNESP]
Bolzani, Vanderlan da Silva [UNESP]
author_role author
author2 Pivatto, Marcos [UNESP]
Danuello, Amanda [UNESP]
Castro-Gamboa, Ian [UNESP]
Silva, Dulce Helena Siqueira [UNESP]
Cavalheiro, Alberto José [UNESP]
Araújo, Angela Regina [UNESP]
Furlan, Maysa [UNESP]
Lopes, Márcia Nasser [UNESP]
Bolzani, Vanderlan da Silva [UNESP]
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Valli, Marilia [UNESP]
Pivatto, Marcos [UNESP]
Danuello, Amanda [UNESP]
Castro-Gamboa, Ian [UNESP]
Silva, Dulce Helena Siqueira [UNESP]
Cavalheiro, Alberto José [UNESP]
Araújo, Angela Regina [UNESP]
Furlan, Maysa [UNESP]
Lopes, Márcia Nasser [UNESP]
Bolzani, Vanderlan da Silva [UNESP]
dc.subject.por.fl_str_mv natural products
medicinal chemistry
tropical biodiversity
topic natural products
medicinal chemistry
tropical biodiversity
description The use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
2014-05-20T14:21:25Z
2014-05-20T14:21:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0100-40422012001100036
Química Nova. Sociedade Brasileira de Química, v. 35, n. 11, p. 2278-2287, 2012.
0100-4042
http://hdl.handle.net/11449/26395
10.1590/S0100-40422012001100036
S0100-40422012001100036
WOS:000312034600036
S0100-40422012001100036.pdf
4702004904231248
2518006820764120
0037579054083160
1308042794786872
3310170899693944
4484083685251673
0000-0001-7616-9652
0000-0002-1516-7765
url http://dx.doi.org/10.1590/S0100-40422012001100036
http://hdl.handle.net/11449/26395
identifier_str_mv Química Nova. Sociedade Brasileira de Química, v. 35, n. 11, p. 2278-2287, 2012.
0100-4042
10.1590/S0100-40422012001100036
S0100-40422012001100036
WOS:000312034600036
S0100-40422012001100036.pdf
4702004904231248
2518006820764120
0037579054083160
1308042794786872
3310170899693944
4484083685251673
0000-0001-7616-9652
0000-0002-1516-7765
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Química Nova
0.646
0,255
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 2278-2287
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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