Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNESP |
| Texto Completo: | http://dx.doi.org/10.1590/S0100-40422012001100036 http://hdl.handle.net/11449/26395 |
Resumo: | The use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery. |
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Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?natural productsmedicinal chemistrytropical biodiversityThe use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual Paulista Júlio de Mesquita Filho Instituto de Química Departamento de Química OrgânicaUniversidade Estadual Paulista Júlio de Mesquita Filho Instituto de Química Departamento de Química OrgânicaSociedade Brasileira de QuímicaUniversidade Estadual Paulista (Unesp)Valli, Marilia [UNESP]Pivatto, Marcos [UNESP]Danuello, Amanda [UNESP]Castro-Gamboa, Ian [UNESP]Silva, Dulce Helena Siqueira [UNESP]Cavalheiro, Alberto José [UNESP]Araújo, Angela Regina [UNESP]Furlan, Maysa [UNESP]Lopes, Márcia Nasser [UNESP]Bolzani, Vanderlan da Silva [UNESP]2014-05-20T14:21:25Z2014-05-20T14:21:25Z2012-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2278-2287application/pdfhttp://dx.doi.org/10.1590/S0100-40422012001100036Química Nova. Sociedade Brasileira de Química, v. 35, n. 11, p. 2278-2287, 2012.0100-4042http://hdl.handle.net/11449/2639510.1590/S0100-40422012001100036S0100-40422012001100036WOS:000312034600036S0100-40422012001100036.pdf4702004904231248251800682076412000375790540831601308042794786872331017089969394444840836852516730000-0001-7616-96520000-0002-1516-7765SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengQuímica Nova0.6460,255info:eu-repo/semantics/openAccess2023-10-24T06:06:40Zoai:repositorio.unesp.br:11449/26395Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:48:50.791405Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
| dc.title.none.fl_str_mv |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? |
| title |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? |
| spellingShingle |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? Valli, Marilia [UNESP] natural products medicinal chemistry tropical biodiversity |
| title_short |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? |
| title_full |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? |
| title_fullStr |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? |
| title_full_unstemmed |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? |
| title_sort |
Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? |
| author |
Valli, Marilia [UNESP] |
| author_facet |
Valli, Marilia [UNESP] Pivatto, Marcos [UNESP] Danuello, Amanda [UNESP] Castro-Gamboa, Ian [UNESP] Silva, Dulce Helena Siqueira [UNESP] Cavalheiro, Alberto José [UNESP] Araújo, Angela Regina [UNESP] Furlan, Maysa [UNESP] Lopes, Márcia Nasser [UNESP] Bolzani, Vanderlan da Silva [UNESP] |
| author_role |
author |
| author2 |
Pivatto, Marcos [UNESP] Danuello, Amanda [UNESP] Castro-Gamboa, Ian [UNESP] Silva, Dulce Helena Siqueira [UNESP] Cavalheiro, Alberto José [UNESP] Araújo, Angela Regina [UNESP] Furlan, Maysa [UNESP] Lopes, Márcia Nasser [UNESP] Bolzani, Vanderlan da Silva [UNESP] |
| author2_role |
author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
| dc.contributor.author.fl_str_mv |
Valli, Marilia [UNESP] Pivatto, Marcos [UNESP] Danuello, Amanda [UNESP] Castro-Gamboa, Ian [UNESP] Silva, Dulce Helena Siqueira [UNESP] Cavalheiro, Alberto José [UNESP] Araújo, Angela Regina [UNESP] Furlan, Maysa [UNESP] Lopes, Márcia Nasser [UNESP] Bolzani, Vanderlan da Silva [UNESP] |
| dc.subject.por.fl_str_mv |
natural products medicinal chemistry tropical biodiversity |
| topic |
natural products medicinal chemistry tropical biodiversity |
| description |
The use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery. |
| publishDate |
2012 |
| dc.date.none.fl_str_mv |
2012-01-01 2014-05-20T14:21:25Z 2014-05-20T14:21:25Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0100-40422012001100036 Química Nova. Sociedade Brasileira de Química, v. 35, n. 11, p. 2278-2287, 2012. 0100-4042 http://hdl.handle.net/11449/26395 10.1590/S0100-40422012001100036 S0100-40422012001100036 WOS:000312034600036 S0100-40422012001100036.pdf 4702004904231248 2518006820764120 0037579054083160 1308042794786872 3310170899693944 4484083685251673 0000-0001-7616-9652 0000-0002-1516-7765 |
| url |
http://dx.doi.org/10.1590/S0100-40422012001100036 http://hdl.handle.net/11449/26395 |
| identifier_str_mv |
Química Nova. Sociedade Brasileira de Química, v. 35, n. 11, p. 2278-2287, 2012. 0100-4042 10.1590/S0100-40422012001100036 S0100-40422012001100036 WOS:000312034600036 S0100-40422012001100036.pdf 4702004904231248 2518006820764120 0037579054083160 1308042794786872 3310170899693944 4484083685251673 0000-0001-7616-9652 0000-0002-1516-7765 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Química Nova 0.646 0,255 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
2278-2287 application/pdf |
| dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
| publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
| dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
| instname_str |
Universidade Estadual Paulista (UNESP) |
| instacron_str |
UNESP |
| institution |
UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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1808128566405103616 |