Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups

Detalhes bibliográficos
Autor(a) principal: DF, Braganholi [UNESP]
Data de Publicação: 2019
Outros Autores: JM, Freitas, NC, Andrekenas [UNESP], BB, Januário [UNESP], IB, Ambrosio [UNESP], FS, Polverari [UNESP], RMB, Cicarelli [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.fsigss.2019.10.005
http://hdl.handle.net/11449/198107
Resumo: Initial data about the population of the Center-West Brazil region for mtDNA CR were published in 2019. From this group, 74 samples were selected from individuals who shared haplotypes. The purpose was to analyze the complete mtDNA by Massively Parallel Sequencing and to evaluate if it is possible to differentiate these haplotypes. Libraries were created for all samples and to date 22 samples were sequenced by the Illumina system. Analyzing only the CR, 8 haplotypes were identified in these 22 samples. The complete mtDNA analysis allowed the identification of 16 haplotypes, 6 of which were shared by two samples each, that is, the diversity of haplotypes in this sample increased. In addition, we identified some genetic variants not reported in the EMPOP in mtDNAs classified in haplogroups A2, B2, L2a1f and L0a2a2a.
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spelling Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroupsBrazilCenter-west regionHuman identificationmtDNAInitial data about the population of the Center-West Brazil region for mtDNA CR were published in 2019. From this group, 74 samples were selected from individuals who shared haplotypes. The purpose was to analyze the complete mtDNA by Massively Parallel Sequencing and to evaluate if it is possible to differentiate these haplotypes. Libraries were created for all samples and to date 22 samples were sequenced by the Illumina system. Analyzing only the CR, 8 haplotypes were identified in these 22 samples. The complete mtDNA analysis allowed the identification of 16 haplotypes, 6 of which were shared by two samples each, that is, the diversity of haplotypes in this sample increased. In addition, we identified some genetic variants not reported in the EMPOP in mtDNAs classified in haplogroups A2, B2, L2a1f and L0a2a2a.Laboratório de Investigação de Paternidade UNESP-FCFArPolícia Federal Instituto Nacional de CriminalísticaLaboratório de Investigação de Paternidade UNESP-FCFArUniversidade Estadual Paulista (Unesp)Instituto Nacional de CriminalísticaDF, Braganholi [UNESP]JM, FreitasNC, Andrekenas [UNESP]BB, Januário [UNESP]IB, Ambrosio [UNESP]FS, Polverari [UNESP]RMB, Cicarelli [UNESP]2020-12-12T00:59:20Z2020-12-12T00:59:20Z2019-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article345-346http://dx.doi.org/10.1016/j.fsigss.2019.10.005Forensic Science International: Genetics Supplement Series, v. 7, n. 1, p. 345-346, 2019.1875-175X1875-1768http://hdl.handle.net/11449/19810710.1016/j.fsigss.2019.10.0052-s2.0-85074705159Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengForensic Science International: Genetics Supplement Seriesinfo:eu-repo/semantics/openAccess2021-10-23T08:46:53Zoai:repositorio.unesp.br:11449/198107Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:09:51.238569Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
title Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
spellingShingle Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
DF, Braganholi [UNESP]
Brazil
Center-west region
Human identification
mtDNA
title_short Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
title_full Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
title_fullStr Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
title_full_unstemmed Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
title_sort Analysis of the complete mtDNA in Brazilian samples: Haplotypes differentiation and identification of new variations in Native American haplogroups
author DF, Braganholi [UNESP]
author_facet DF, Braganholi [UNESP]
JM, Freitas
NC, Andrekenas [UNESP]
BB, Januário [UNESP]
IB, Ambrosio [UNESP]
FS, Polverari [UNESP]
RMB, Cicarelli [UNESP]
author_role author
author2 JM, Freitas
NC, Andrekenas [UNESP]
BB, Januário [UNESP]
IB, Ambrosio [UNESP]
FS, Polverari [UNESP]
RMB, Cicarelli [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Instituto Nacional de Criminalística
dc.contributor.author.fl_str_mv DF, Braganholi [UNESP]
JM, Freitas
NC, Andrekenas [UNESP]
BB, Januário [UNESP]
IB, Ambrosio [UNESP]
FS, Polverari [UNESP]
RMB, Cicarelli [UNESP]
dc.subject.por.fl_str_mv Brazil
Center-west region
Human identification
mtDNA
topic Brazil
Center-west region
Human identification
mtDNA
description Initial data about the population of the Center-West Brazil region for mtDNA CR were published in 2019. From this group, 74 samples were selected from individuals who shared haplotypes. The purpose was to analyze the complete mtDNA by Massively Parallel Sequencing and to evaluate if it is possible to differentiate these haplotypes. Libraries were created for all samples and to date 22 samples were sequenced by the Illumina system. Analyzing only the CR, 8 haplotypes were identified in these 22 samples. The complete mtDNA analysis allowed the identification of 16 haplotypes, 6 of which were shared by two samples each, that is, the diversity of haplotypes in this sample increased. In addition, we identified some genetic variants not reported in the EMPOP in mtDNAs classified in haplogroups A2, B2, L2a1f and L0a2a2a.
publishDate 2019
dc.date.none.fl_str_mv 2019-12-01
2020-12-12T00:59:20Z
2020-12-12T00:59:20Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.fsigss.2019.10.005
Forensic Science International: Genetics Supplement Series, v. 7, n. 1, p. 345-346, 2019.
1875-175X
1875-1768
http://hdl.handle.net/11449/198107
10.1016/j.fsigss.2019.10.005
2-s2.0-85074705159
url http://dx.doi.org/10.1016/j.fsigss.2019.10.005
http://hdl.handle.net/11449/198107
identifier_str_mv Forensic Science International: Genetics Supplement Series, v. 7, n. 1, p. 345-346, 2019.
1875-175X
1875-1768
10.1016/j.fsigss.2019.10.005
2-s2.0-85074705159
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Forensic Science International: Genetics Supplement Series
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 345-346
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128325117280256

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